Personlig profil

Kort præsentation

The rapid rise in the prevalence of obesity, diabetes, and physical inactivity has significantly contributed to the increasing global burden of noncommunicable diseases. Skeletal muscle, the largest tissue in the body, possesses remarkable plasticity and represents a key pharmacological target to combat these diseases. Skeletal muscle redox signaling has emerged as a novel regulator of skeletal muscle metabolism but the molecular mechanisms involved are still not well understood. Our research focuses on connecting intracellular redox signaling and skeletal muscle metabolism in the context of metabolic diseases.  

 

Recent Selected Publications 

Henriquez-Olguin, C., Knudsen, J.R., Raun, S.H. et al. Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. Nature Commun 10, 4623 (2019).

Henriquez-Olguin C., Boronat, S.  et al.  NADPH oxidases in skeletal muscle: Emerging roles in redox signaling and metabolism. Antioxid Redox Signal. 31(18):1371-1410 (2019)

Henriquez-Olguin C, Baghersad L, Arab-Ceschia L, Raun SH., et al.  Adaptations to high-intensity interval training in skeletal muscle require NADPH oxidase 2. Redox Biology 24, 101188 (2019)

Raun, S.H., Henriquez-Olguin, C., Karavaeva, I. et al. Housing temperature influences exercise training adaptations in mice. Nature Commun 11, 1560 (2020).

 

Primære forskningsområder

- Skeletal Muscle Metabolism 

- Redox Signaling 

- Insulin Action 

- Exercise Physiology 

 

ResearcherID: K-7671-2012

Scopus Author ID: 35102305800

Uddannelse (Akademiske kvalifikationer)

PhD in Molecular Physiology , University of Copenhagen

Dimissionsdato: 30 sep. 2018

PhD in Biomedical Sciences , University of Chile

Dimissionsdato: 6 aug. 2018

Master in Physiology , University of Chile

Dimissionsdato: 17 jun. 2013

Emneord

  • Det Natur- og Biovidenskabelige Fakultet

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