Publikationer pr. år
Publikationer pr. år
Blegdamsvej 3, 2200 København N.
Blegdamsvej 3
2200 København N.
Publikationer pr. år
Morphogenesis and differentiation of the gastrointestinal mucosa.
Special focus is on the bioinformatics interpretation of alterations in molecular profiles (transcriptome, metabolome) during mucosal inflammation. The basic research using mouse models for intestinal inflammation is translated into applied research in inflammatory bowel diseases.
Rectal insulin as treatment for inflammatory bowel disease.
Using mouse models for colonic inflammation in combination with mouse genetics we have made the invention that colitis in mice can be treated using rectal instillation of insulin. We are currently doing basic research with the purpose of delineating the mechanism of action for rectal insulin. In addition we have initiated clinical collaborations with clinicians in Copenhagen and Zürich with the purpose to conduct proof of concept studies with ulcerative colitis patients
Collaborators
Professor Gerhard Rogler, University of Zürich
Professor Yulan Wang, Key Laboratory of Magnetic Resonance in Biological Systems
Wuhan Institute of Physics and Mathematics
Director, ”Course in Head, Neck, the Locomotor System and the Peripheral Nervous System” for third semester medical students.
Development of new teaching concepts:
Date of birth : March, 1964
Nationality : Danish
Gender: Male
Current affiliation
Department of Molecular & Cellular Medicine
University of Copenhagen
The Panum Institute, bldg. 18.6
Blegdamsvej 3
DK 2200N Denmark
Education
1992 | Medical Doctor (cand. med.), University of Copenhagen |
1998 | Doctor Medicinae (DMSc), The Faculty of Health Sciences, University of Copenhagen |
Employments
1993 | Research assistant, Michaelsen Foundation, Department of Medical Biochemistry & Genetics, University of Copenhagen |
1994 | Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen |
1995 | Intern, Department of Medical Gastroenterology, KAS Herlev University Hospital |
1995 | Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen |
1997 | Alfred Benzon Investigator, INSERM U381, Strasbourg, France |
1998 | Associate professor, Department of Medical Biochemistry & Genetics, University of Copenhagen |
2007 | Associate professor, Department of Cellular & Molecular Medicine, University of Copenhagen |
2009 | Professor, Department of Cellular & Molecular Medicine, University of Copenhagen |
Scholarships
1987 | Scholarstipend Danish Medical Research Council |
1988 | Scholarstipend The Faculty of Health Sciences, University of Copenhagen |
Administrative tasks
Period | Task | Organisation |
1987-1990 | Executive committee, Institute of Medical Biochemistry C, Student representative | University of Copenhagen |
1994-1996 | Leader of the molecular Biology course for Human Biology students | University of Copenhagen |
1998-1999 | Member of "Samarbejdsudvalget", Department of Medical Biochemistry & Genetics | University of Copenhagen |
1999-2002 | Member of the Research Committee, The Faculty of Health Sciences | University of Copenhagen |
2001- | Leader of the course in Neurobiochemistry for Medical students | University of Copenhagen |
2003- | Member of the scientific board for the Journal of the Danish Medical Association (Ugeskrift for Læger) | Danish Medical Association |
2003-2005 | Member of the executive committee, The Research Committee, The faculty of Health Sciences | University of Health Sciences |
2005- | Teaching Coordinator, Department of Medical Biochemistry & Genetics | University of Copenhagen |
2007- | Member of the study board for medicine, Faculty of Healths Sciences | University of Copenhagen |
2007- | Member of the editorial board for "The Open Applied Informatics Journal" | Bentham Science Publishers Ltd |
Reviewing activity
Journal |
Bioinformatics |
International Journal of Cancer |
Journal of Oral Pathology & Medicine |
European Journal of Biochemistry |
Gastroenterology |
European Journal of Human Genetics |
Journal of Histochemistry & Cytochemistry |
Ugeskrift for Læger |
Oncogene |
American Journal of Physiology |
Cancer Letters |
European Journal of Gastroenterology & Hepatology |
Clinical Experimental Immunology |
Supervision and evaluation committees
Supervisor for 7 PhD students, 12 masters students and 2 scholar stipend students.
In the evaluation committee for one professorship, two associate professorships, 13 PhD theses and 5 masters theses.
External grants
Project period | Amount | Currency | Project title | Source |
1998-1999 | 260000 | DKK | Cytokine mediated interaction between intestinal endoderm and mesenchyme | The Novo Nordisk Foundation |
1999-2000 | 75000 | DKK | Identification of markers for intestinal epithelial stem cells | The Novo Nordisk Foundation |
2000-2002 | 1050000 | DKK | Development and maintenance of the gastrointestinal mucosa | The Danish Medical Research Council |
2002 | 300000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
2001-2002 | 200000 | DKK | Identification of gene combinations which increases the risk for colorectal cancer development | The Novo Nordisk Foundation |
2003-2004 | 600000 | DKK | Gene expression and cellular phenotype in the small intestinal epithelium | The Medical Research Council |
2003 | 125000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
2004 | 125000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
2004-2006 | 1080000 | DKK | Delineation of transcription factor networks for use in molecular gastroenterology | The Danish Medical Research Council |
2006-2007 | 96100 | EUR | Fruit Quality and Safety, ISAFRUIT. Partner. | European commission |
2006-2009 | 510000 | DKK | "samfinancieret ph.d-stip" | The Danish Medical Research Council |
Direktør og medstifter af Enterotarget ApS, som er et spin-out firma fra Københavns Universitet. Enterotarget har en licensaftale med Københavns Universitet vedrørende patentet "Rectal insulin for treatment of inflammatory bowel disease" EP3538132A1
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review