Intet billede af Jørgen Olsen
  • Kilde: Scopus
1988 …2024

Publikationer pr. år

Personlig profil

Primære forskningsområder

Morphogenesis and differentiation of the gastrointestinal mucosa.
Special focus is on the bioinformatics interpretation of alterations in molecular profiles (transcriptome, metabolome) during mucosal inflammation. The basic research using mouse models for intestinal inflammation is translated into applied research in inflammatory bowel diseases.

Aktuel forskning

Rectal insulin as treatment for inflammatory bowel disease.
Using mouse models for colonic inflammation in combination with mouse genetics we have made the invention that colitis in mice can be treated using rectal instillation of insulin. We are currently doing basic research with the purpose of delineating the mechanism of action for rectal insulin. In addition we have initiated clinical collaborations with clinicians in Copenhagen and Zürich with the purpose to conduct proof of concept studies with ulcerative colitis patients

Collaborators
Professor Gerhard Rogler, University of Zürich
Professor Yulan Wang, Key Laboratory of Magnetic Resonance in Biological Systems
Wuhan Institute of Physics and Mathematics

Undervisnings- og vejledningsområder

Director, ”Course in Head, Neck, the Locomotor System and the Peripheral Nervous System” for third semester medical students.

Development of new teaching concepts:

  • “The Modern Anatomical Theater”
  • “Q + A livestreamed sessions with student and teacher interactions”
  • “Livestreamed Exam TV”
  • “The digital x-ray library”
  • “The digital anatomical museum”

 

CV

Jørgen Olsen M.D., DMSc

Date of birth : March, 1964
Nationality : Danish
Gender: Male

Current affiliation
Department of Molecular & Cellular Medicine
University of Copenhagen
The Panum Institute, bldg. 18.6
Blegdamsvej 3
DK   2200N Denmark  

Education

1992Medical Doctor (cand. med.), University of Copenhagen
1998Doctor Medicinae (DMSc), The Faculty of Health Sciences, University of Copenhagen

Employments

1993Research assistant, Michaelsen Foundation, Department of Medical Biochemistry & Genetics, University of Copenhagen
 1994Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen
 1995Intern, Department of Medical Gastroenterology, KAS Herlev University Hospital
 1995Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen
 1997Alfred Benzon Investigator, INSERM U381, Strasbourg, France
 1998Associate professor, Department of Medical Biochemistry & Genetics, University of Copenhagen
 2007Associate professor, Department of Cellular & Molecular Medicine, University of Copenhagen
 2009Professor, Department of Cellular & Molecular Medicine, University of Copenhagen

Scholarships

1987Scholarstipend Danish Medical Research Council
1988Scholarstipend The Faculty of Health Sciences, University of Copenhagen

Administrative tasks

Period TaskOrganisation
1987-1990Executive committee, Institute of Medical Biochemistry C, Student representativeUniversity of Copenhagen
1994-1996Leader of the molecular Biology course for Human Biology studentsUniversity of Copenhagen
1998-1999Member of "Samarbejdsudvalget", Department of Medical Biochemistry & GeneticsUniversity of Copenhagen
1999-2002Member of the Research Committee, The Faculty of Health SciencesUniversity of Copenhagen
2001-Leader of the course in Neurobiochemistry for Medical studentsUniversity of Copenhagen
2003-Member of the scientific board for the Journal of the Danish Medical Association (Ugeskrift for Læger)Danish Medical Association
2003-2005Member of the executive committee, The Research Committee, The faculty of Health SciencesUniversity of Health Sciences
2005-Teaching Coordinator, Department of Medical Biochemistry & GeneticsUniversity of Copenhagen
2007-Member of the study board for medicine, Faculty of Healths SciencesUniversity of Copenhagen
2007-Member of the editorial board for "The Open Applied Informatics Journal"Bentham Science Publishers Ltd

Reviewing activity

Journal
Bioinformatics
International Journal of Cancer
Journal of Oral Pathology & Medicine
European Journal of Biochemistry
Gastroenterology
European Journal of Human Genetics
Journal of Histochemistry & Cytochemistry
Ugeskrift for Læger
Oncogene
American Journal of Physiology
Cancer Letters
European Journal of Gastroenterology & Hepatology
Clinical Experimental Immunology

Supervision and evaluation committees 

Supervisor for 7 PhD students, 12 masters students and 2 scholar stipend students.
In the evaluation committee for one professorship, two associate professorships, 13 PhD theses and 5 masters theses.  

External grants

Project period Amount Currency Project title Source
1998-1999260000  DKKCytokine mediated interaction between intestinal endoderm and mesenchymeThe Novo Nordisk Foundation
1999-200075000  DKKIdentification of markers for intestinal epithelial stem cellsThe Novo Nordisk Foundation
2000-20021050000  DKKDevelopment and maintenance of the gastrointestinal mucosaThe Danish Medical Research Council
2002300000  DKKGene expression as predictor for development of colorectal cancerThe Alfred Nielsen and Wife's Foundation
2001-2002200000  DKKIdentification of gene combinations which increases the risk for colorectal cancer developmentThe Novo Nordisk Foundation
2003-2004600000 DKKGene expression and cellular phenotype in the small intestinal epitheliumThe Medical Research Council
2003125000  DKKGene expression as predictor for development of colorectal cancerThe Alfred Nielsen and Wife's Foundation
2004125000  DKKGene expression as predictor for development of colorectal cancerThe Alfred Nielsen and Wife's Foundation
2004-20061080000  DKKDelineation of transcription factor networks for use in molecular gastroenterologyThe Danish Medical Research Council
2006-200796100  EURFruit Quality and Safety, ISAFRUIT. Partner.European commission
2006-2009510000  DKK"samfinancieret ph.d-stip"The Danish Medical Research Council

Mulige interessekonflikter

Direktør og medstifter af Enterotarget ApS, som er et spin-out firma fra Københavns Universitet. Enterotarget har en licensaftale med Københavns Universitet vedrørende patentet "Rectal insulin for treatment of inflammatory bowel disease" EP3538132A1

Emneord

  • Det Sundhedsvidenskabelige Fakultet
  • Bioinformatics
  • Gene expression analysis
  • Intestinal differentiation
  • Inflammatory bowel diseases

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