Personlig profil
Primære forskningsområder
Morphogenesis and differentiation of the gastrointestinal mucosa.
Special focus is on the bioinformatics interpretation of alterations in molecular profiles (transcriptome, metabolome) during mucosal inflammation. The basic research using mouse models for intestinal inflammation is translated into applied research in inflammatory bowel diseases.
Aktuel forskning
Rectal insulin as treatment for inflammatory bowel disease.
Using mouse models for colonic inflammation in combination with mouse genetics we have made the invention that colitis in mice can be treated using rectal instillation of insulin. We are currently doing basic research with the purpose of delineating the mechanism of action for rectal insulin. In addition we have initiated clinical collaborations with clinicians in Copenhagen and Zürich with the purpose to conduct proof of concept studies with ulcerative colitis patients
Collaborators
Professor Gerhard Rogler, University of Zürich
Professor Yulan Wang, Key Laboratory of Magnetic Resonance in Biological Systems
Wuhan Institute of Physics and Mathematics
Undervisnings- og vejledningsområder
Director, ”Course in Head, Neck, the Locomotor System and the Peripheral Nervous System” for third semester medical students.
Development of new teaching concepts:
- “The Modern Anatomical Theater”
- “Q + A livestreamed sessions with student and teacher interactions”
- “Livestreamed Exam TV”
- “The digital x-ray library”
- “The digital anatomical museum”
CV
Jørgen Olsen M.D., DMSc
Date of birth : March, 1964
Nationality : Danish
Gender: Male
Current affiliation
Department of Molecular & Cellular Medicine
University of Copenhagen
The Panum Institute, bldg. 18.6
Blegdamsvej 3
DK 2200N Denmark
Education
| 1992 | Medical Doctor (cand. med.), University of Copenhagen |
| 1998 | Doctor Medicinae (DMSc), The Faculty of Health Sciences, University of Copenhagen |
Employments
| 1993 | Research assistant, Michaelsen Foundation, Department of Medical Biochemistry & Genetics, University of Copenhagen |
| 1994 | Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen |
| 1995 | Intern, Department of Medical Gastroenterology, KAS Herlev University Hospital |
| 1995 | Assistant professor Department of Medical Biochemistry & Genetics, University of Copenhagen |
| 1997 | Alfred Benzon Investigator, INSERM U381, Strasbourg, France |
| 1998 | Associate professor, Department of Medical Biochemistry & Genetics, University of Copenhagen |
| 2007 | Associate professor, Department of Cellular & Molecular Medicine, University of Copenhagen |
| 2009 | Professor, Department of Cellular & Molecular Medicine, University of Copenhagen |
Scholarships
| 1987 | Scholarstipend Danish Medical Research Council |
| 1988 | Scholarstipend The Faculty of Health Sciences, University of Copenhagen |
Administrative tasks
| Period | Task | Organisation |
| 1987-1990 | Executive committee, Institute of Medical Biochemistry C, Student representative | University of Copenhagen |
| 1994-1996 | Leader of the molecular Biology course for Human Biology students | University of Copenhagen |
| 1998-1999 | Member of "Samarbejdsudvalget", Department of Medical Biochemistry & Genetics | University of Copenhagen |
| 1999-2002 | Member of the Research Committee, The Faculty of Health Sciences | University of Copenhagen |
| 2001- | Leader of the course in Neurobiochemistry for Medical students | University of Copenhagen |
| 2003- | Member of the scientific board for the Journal of the Danish Medical Association (Ugeskrift for Læger) | Danish Medical Association |
| 2003-2005 | Member of the executive committee, The Research Committee, The faculty of Health Sciences | University of Health Sciences |
| 2005- | Teaching Coordinator, Department of Medical Biochemistry & Genetics | University of Copenhagen |
| 2007- | Member of the study board for medicine, Faculty of Healths Sciences | University of Copenhagen |
| 2007- | Member of the editorial board for "The Open Applied Informatics Journal" | Bentham Science Publishers Ltd |
Reviewing activity
| Journal |
| Bioinformatics |
| International Journal of Cancer |
| Journal of Oral Pathology & Medicine |
| European Journal of Biochemistry |
| Gastroenterology |
| European Journal of Human Genetics |
| Journal of Histochemistry & Cytochemistry |
| Ugeskrift for Læger |
| Oncogene |
| American Journal of Physiology |
| Cancer Letters |
| European Journal of Gastroenterology & Hepatology |
| Clinical Experimental Immunology |
Supervision and evaluation committees
Supervisor for 7 PhD students, 12 masters students and 2 scholar stipend students.
In the evaluation committee for one professorship, two associate professorships, 13 PhD theses and 5 masters theses.
External grants
| Project period | Amount | Currency | Project title | Source |
| 1998-1999 | 260000 | DKK | Cytokine mediated interaction between intestinal endoderm and mesenchyme | The Novo Nordisk Foundation |
| 1999-2000 | 75000 | DKK | Identification of markers for intestinal epithelial stem cells | The Novo Nordisk Foundation |
| 2000-2002 | 1050000 | DKK | Development and maintenance of the gastrointestinal mucosa | The Danish Medical Research Council |
| 2002 | 300000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
| 2001-2002 | 200000 | DKK | Identification of gene combinations which increases the risk for colorectal cancer development | The Novo Nordisk Foundation |
| 2003-2004 | 600000 | DKK | Gene expression and cellular phenotype in the small intestinal epithelium | The Medical Research Council |
| 2003 | 125000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
| 2004 | 125000 | DKK | Gene expression as predictor for development of colorectal cancer | The Alfred Nielsen and Wife's Foundation |
| 2004-2006 | 1080000 | DKK | Delineation of transcription factor networks for use in molecular gastroenterology | The Danish Medical Research Council |
| 2006-2007 | 96100 | EUR | Fruit Quality and Safety, ISAFRUIT. Partner. | European commission |
| 2006-2009 | 510000 | DKK | "samfinancieret ph.d-stip" | The Danish Medical Research Council |
Mulige interessekonflikter
Direktør og medstifter af Enterotarget ApS, som er et spin-out firma fra Københavns Universitet. Enterotarget har en licensaftale med Københavns Universitet vedrørende patentet "Rectal insulin for treatment of inflammatory bowel disease" EP3538132A1
Emneord
- Det Sundhedsvidenskabelige Fakultet
- Bioinformatics
- Gene expression analysis
- Intestinal differentiation
- Inflammatory bowel diseases
Samarbejde og topforskningsområder i de sidste fem år
Publikation
-
Health profession students’ outlooks on the medical profession during the COVID-19 pandemic: a global perspective
Utomo, R., McWatt, S. C., Talis, A., Xiao, Q. Y., Saraci, K., Waschke, J., Sigmund, A. M., Gill Sagoo, M., Wingate, R., Brassett, C., Chien, C. L., Traxler, H., Sakurai, T., Zeroual, M., Olsen, J., El-Batti, S., Viranta-Kovanen, S., Yamada, Y., Keay, K. A. & Kitahara, S. & 12 flere, , 2024, I: Journal of Communication in Healthcare. 17, 2, s. 154-168 15 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
2 Citationer (Scopus) -
A thematic analysis of students' discussions on death and body donation in international online focus groups
Wu, A., McWatt, S. C., Utomo, R., Talis, A., Xiao, Q. Y., Saraci, K., Brassett, C., Sagoo, M. G., Wingate, R., Chien, C. L., Traxler, H., Waschke, J., Vielmuth, F., Sigmund, A., Yamada, Y., Sakurai, T., Zeroual, M., Olsen, J., El-Batti, S. & Viranta-Kovanen, S. & 8 flere, , 2023, I: Anatomical Sciences Education. 16, 4, s. 768-784Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil9 Citationer (Scopus)64 Downloads (Pure) -
Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity
Olsson, J. B., Gugerel, M. B., Jessen, S. B., Jørgensen, J., Gögenur, I., Hansen, C., Kirkeby, L. T., Olsen, J., Pedersen, O. B. V., Vestlev, P. M., Dahlgaard, K. & Troelsen, J. T., 2022, I: PLoS ONE. 17, 9 , e0274033.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil2 Citationer (Scopus)53 Downloads (Pure) -
Cultural competency preparedness in medical and health professions students - a collaborative study involving anatomy departments at 20 international universities
Wu, A., Patel, R., Brassett, C., McWatt, S., Sagoo, M. G., Wingate, R., Chien, C. L., Traxler, H., Waschke, J., Vielmuth, F., Sigmund, A., Sakurai, T., Yamada, Y., Zeroual, M., Olsen, J., Batti, S. E., Viranta-Kovanen, S., Keay, K., Kitahara, S. & Martinez-Abadias, N. & 20 flere, , 2022, I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36, S1Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
Åben adgang -
Experiential factors affecting the empathy of students in their pre-clinical year(s) of 21 universities
Vigoda, J., Adeniyi, A., Tudor, L., Brassett, C., McWatt, S., Sagoo, M. G., Wingate, R., Chien, C. L., Traxler, H., Waschke, J., Vielmuth, F., Sigmund, A., Sakurai, T., Yamada, Y., Zeroual, M., Olsen, J., El-Batti, S., Viranta-Kovanen, S., Keay, K. & Kitahara, S. & 23 flere, , 2022, I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36, S1Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review
Åben adgang -
The Anatomy Course During COVID-19: The Impact of Cadaver-Based Learning on the Initiation of Reflection on Death
Wu, A., Xiao, Q. Y., McWatt, S., Utomo, R., Talis, A., Saraci, K., Brassett, C., Sagoo, M. G., Wingate, R., Chien, C. L., Traxler, H., Waschke, J., Vielmuth, F., Yamada, Y., Sakurai, T., Zeroual, M., Olsen, J., El-Batti, S., Viranta-Kovanen, S. & Keay, K. & 5 flere, , 2022, I: Medical Science Educator. 32, s. 1033–1044Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgang6 Citationer (Scopus) -
An Observation of Healthcare Professions Students' Perceptions During the COVID-19 Pandemic
Wu, A., Maddula, V., Yu, A. C. X., Goel, R., Shimizu, H., Chien, C.-L., Wingate, R., Sagoo, M. G., Kielstein, H., Traxler, H., Brassett, C., Waschke, J., Vielmuth, F., Keay, K., Zeroual, M., Sakurai, T., Olsen, J., El-Batti, S., Viranta-Kovanen, S. & Kitahara, S. & 3 flere, , 2021, I: Medical Science Educator. 31, s. 401–409 9 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgang2 Citationer (Scopus) -
Initiating Students' Reflections on Life's Passing in the Anatomy Course - an International Observation at 14 Universities
Wu, A., Yu, A. C. X., Chang, C. S., Goel, R., Sagoo, M. G., Sakurai, T., Viranta-Kovanen, S., Chien, C.-L., Traxler, H., Waschke, J., Kitahara, S., Keay, K., Olsen, J., Brassett, C., Batti, S. E., Vielmuth, F., Sigmund, A. M., Zeroual, M., Kunzel, C. & Bernd, P. & 3 flere, , sep. 2021, I: Annals of Anatomy. 237, s. 151741Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil11 Citationer (Scopus)38 Downloads (Pure)