Personlig profil
Kort præsentation
I am the manager of the Transgenic Core Facility of the University of Copenhagen. Since I did my PhD, consisting on the characterization of two genetically modified mouse models for the kinase Cdk4, I am passionate about modifyig the mouse genome in order to provide researchers with experimental models. Besides the design and generation of novel mouse and cell models, at the facility we also support research by rederiving and archiving mouse lines (our cryobank holds more than 750 strains at the moment), and performing assisted reproduction techniques, embryo culture and manipulation as well as mouse embryonic stem cell derivation, culture and modification. Learn more about Transgenic Core Facility at Core Facility for Transgenic Mice – University of Copenhagen (ku.dk)
Emneord
- Det Sundhedsvidenskabelige Fakultet
Samarbejde og topforskningsområder i de sidste fem år
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Male obesity causes adipose mitochondrial dysfunction in F1 mouse progeny via a let-7-DICER axis
Huang, C., Park, J.-H., Altıntaş, A., Stanic, N., de Leon, K. K., Isacson, S., Kalogeropoulos, P., Topel, H., Madsen, T., Zanner, S., Ruppert, P. M., Valdebenito, R., Havelund, J., Larsen, B. D. M., Chien, Y.-T., Huang, W.-C., Budi, Y. P., Jiang, Y.-F., Rocha, A. L. & Lima-Junior, N. C. & 16 flere, , 24 feb. 2026, I: Nature Communications.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
1 Citationer (Scopus) -
Paracetamol (N-Acetyl-Para-Aminophenol) Disrupts Early Embryogenesis by Cell Cycle Inhibition
Nielsen, B. S., Petersen, M. R., Martin-Gonzalez, J., Holmberg, C., Mjoseng, H. K., Frederiksen, H., Rosenthal, C., Jorgensen, E. M., Serup, P., Christensen, S. L., Petersen, K. B., Kristiansen, K., Jorgensen, N. R., Kari, J., Hay-Schmidt, A., Heurte, M., Lindenberg, F., Zedeler, A., Christensen, S. T. & Kristensen, D. M., 2026, I: Obstetrical & Gynecological Survey. 81, 2, s. 69-70Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review
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Functional analysis of pathological mutations in DNA topoisomerase 3A
Wang, Y., Kaiser, S., Martin-Gonzalez, J., Li, Y., Rasmussen, L. J., Lopez-Contreras, A. J., Bizard, A. H. & Hickson, I. D., 2025, I: Cell Reports. 44, 6, 23 s., 115764.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil5 Citationer (Scopus)24 Downloads (Pure) -
Male obesity causes adipose mitochondrial dysfunction in F1progeny via a let-7-DICER axis
Huang, C., Park, J. H., Altıntaş, A., Stanic, N., de Leon, K. K., Isacson, S., Kalogeropoulos, P., Batarlar, H. T., Malmros, R. V., Havelund, J., Larsen, B. D. M., Chien, Y.-T., Huang, W.-C., Szczepanowska, K., Lackmann, J.-W., Trifunovic, A., Hejbøl, E. K., Detlefsen, S., Jepsen, I. E. & Kolstrup, S. H. & 9 flere, , 2025, bioRxiv, 65 s.Publikation: Working paper › Preprint
Fil10 Downloads (Pure) -
Mouse ZGRF1 helicase facilitates DNA repair and maintains efficient fertility
Lim, E. W. K., Kompocholi, S., Brannvoll, A., Bagge, K. S. V., Gruhn, J. R., Martin-Gonzalez, J., Albers, E., Hickson, I. D., López-Contreras, A. & Lisby, M., 2025, I: Heliyon. 11, 2, 16 s., e41979.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil39 Downloads (Pure) -
Paracetamol (N-acetyl-para-aminophenol) disrupts early embryogenesis by cell cycle inhibition
Nielsen, B. S., Petersen, M. R., Martin-Gonzalez, J., Holmberg, C., Mjoseng, H. K., Frederiksen, H., Rosenthal, C., Jorgensen, E. M., Serup, P., Christensen, S. L., Petersen, K. B., Kristiansen, K., Jørgensen, N. R., Kari, J., Hay-Schmidt, A., Heurte, M., Pedersen, P. A., Juul, A., Pinborg, A. & Ziebe, S. & 7 flere, , 2025, I: Human Reproduction. 40, 10, s. 1860-1876 17 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
1 Citationer (Scopus) -
Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration
Engelhard, S., Estruch, M., Qin, S., Engelhard, C. A., Rodriguez-Gonzalez, F. G., Drilsvik, M., Martin-Gonzalez, J., Lu, J. W., Bryder, D., Nerlov, C., Weischenfeldt, J., Reckzeh, K. & Theilgaard-Mönch, K., 2024, I: Cell Reports. 43, 7, 22 s., 114475.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil6 Citationer (Scopus)38 Downloads (Pure) -
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes: [Inkl. Correction]
Ye, Z., Sabatier, P., Martin-Gonzalez, J., Eguchi, A., Lechner, M., Østergaard, O., Xie, J., Guo, Y., Schultz, L., Truffer, R., Bekker-Jensen, D. B., Bache, N. & Olsen, J. V., 2024, I: Nature Communications. 15, 1, 10 s., 2474.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil56 Citationer (Scopus)49 Downloads (Pure)