Lene Ryom

Søgeresultater

• 2025

  Integrase Strand Transfer Inhibitor–Related Changes in Body Mass Index and Risk of Diabetes: A Prospective Study From the RESPOND Cohort Consortium

  Rupasinghe, D., Bansi-Matharu, L., Law, M., Zangerle, R., Rauch, A., Tarr, P. E., Greenberg, L., Neesgaard, B., Jaschinski, N., De Wit, S., Wit, F., Monforte, A. D., Fontas, E., Castagna, A., Stecher, M., Florence, E., Begovac, J., Mussini, C., Sönnerborg, A. & Abutidze, A. & 7 flere, Groh, A., Vannappagari, V., Cohen, C., Young, L., Hosein, S., Ryom, L. & Petoumenos, K., 2025, I: Clinical Infectious Diseases. 80, 2, s. 404-416 13 s.

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  4 Citationer (Scopus)

• The potential for annual long-acting HIV pre-exposure prophylaxis

  Ryom, L., 2025, (E-pub ahead of print) I: The Lancet.

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• Viremia Does Not Independently Predict Cardiovascular Disease in People With HIV: A RESPOND Cohort Study

  Elvstam, O., Ryom, L., Neesgaard, B., Tau, L., Günthard, H. F., Zangerle, R., Vehreschild, J. J., Wit, F., Sönnerborg, A., Kovari, H., Abutidze, A., Petoumenos, K., Jaschinski, N., Hosein, S., Bogner, J., Grabmeier-Pfistershammer, K., Garges, H., Rooney, J., Young, L. & Law, M. & 2 flere, Kirk, O. & for the RESPOND Study Group, 2025, I: Open Forum Infectious Diseases. 12, 2, 10 s., ofaf016.

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• 2024

  Associations between change in BMI and the risk of hypertension and dyslipidaemia in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other contemporary antiretroviral regimens: a multicentre, prospective observational study from the RESPOND consortium cohorts

  Byonanebye, D. M., Polizzotto, M. N., Maltez, F., Rauch, A., Grabmeier-Pfistershammer, K., Wit, F., De Wit, S., Castagna, A., d'Arminio Monforte, A., Mussini, C., Wasmuth, J.-C., Fontas, E., Abela, I., Sarcletti, M., Bansi-Matharu, L., Jaschinski, N., Peters, L., Hosein, S. R., Vannappagari, V. & Cohen, C. & 6 flere, Bissio, E., Mocroft, A., Law, M., Ryom, L., Petoumenos, K. & RESPOND Study Group, maj 2024, I: The Lancet HIV. 11, 5, s. e321-e332 12 s.

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  11 Citationer (Scopus)

• Chronic Liver Enzyme Elevation and Use of Contemporary ARVs Among People With HIV

  Roen, A. O., Peters, L., Wandeler, G., van der Valk, M., Zangerle, R., Günthard, H. F., Wit, F., Mussini, C., De Wit, S., d’Arminio Monforte, A., Vehreschild, J. J., Castagna, A., Jaschinski, N., Vannappagari, V., Chen, L., Tallada, J., C’mar, J., Mocroft, A. & Ryom, L., 2024, I: Open Forum Infectious Diseases. 11, 6, 14 s., ofae308.

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• Clinical characteristics of women with HIV in the RESPOND cohort: A descriptive analysis and comparison to men

  Hutchinson, J., Neesgard, B., Kowalska, J., Grabmeier-Pfistershammer, K., Johnson, M., Kusejko, K., De Wit, S., Wit, F., Mussini, C., Castagna, A., Stecher, M., Pradier, C., Domingo, P., Carlander, C., Wasmuth, J., Chkhartishvili, N., Uzdaviniene, V., Haberl, A., Monforte, A. D. & Garges, H. & 11 flere, Gallant, J., Said, M., Schmied, B., van der Valk, M., Konopnicki, D., Jaschinski, N., Mocroft, A., Greenberg, L., Burns, F., Ryom, L. & Petoumenos, K., 2024, I: HIV Medicine. 25, 9, s. 1058-1074 17 s.

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• Graviditet og infektion

  Moseholm, E., Ryom, L., Riise, N., Jeppesen, M., Knudsen, L. S., Johansen, I. S., Katzenstein, T. L., Pedersen, G. & Weis, N., 2024, I: Ugeskrift for Laeger. 186, 32, 9 s.

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• Heavy antiretroviral exposure and exhausted/limited antiretroviral options: Predictors and clinical outcomes

  Mocroft, A., Pelchen-Matthews, A., Hoy, J., Llibre, J. M., Neesgaard, B., Jaschinski, N., Domingo, P., Rasmussen, L. D., Günthard, H. F., Surial, B., Öllinger, A., Knappik, M., De Wit, S., Wit, F., Mussini, C., Vehreschild, J., Monforte, A. D. A., Sonnerborg, A., Castagna, A. & Anne, A. V. & 7 flere, Vannappagari, V., Cohen, C., Greaves, W., Wasmuth, J. C., Spagnuolo, V., Ryom, L. & RESPOND Cohort Collaboration, 2024, I: AIDS. 38, 4, s. 497-508 12 s.

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  3 Citationer (Scopus)

• Long-term impact of immediate versus deferred antiretroviral therapy on kidney health in people with HIV

  Pelchen-Matthews, A., Mocroft, A., Ryom, L., Ross, M. J., Sharma, S., Coca, S., Achhra, A., Cornell, E., Tracy, R., Phillips, A., Alonso, M. M., Toulomi, G., Agan, B. K., Medland, N., Wyatt, C. M. & INSIGHT START Study Group, 2024, I: Kidney International. 106, 1, s. 136-144 9 s.

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• Measures of Longitudinal Immune Dysfunction and Risk of AIDS and Non-AIDS Defining Malignancies in Antiretroviral-Treated People With Human Immunodeficiency Virus

  Chammartin, F., Mocroft, A., Egle, A., Zangerle, R., Smith, C., Mussini, C., Wit, F., Vehreschild, J. J., d’Arminio Monforte, A., Castagna, A., Bailly, L., Bogner, J., de Wit, S., Matulionyte, R., Law, M., Svedhem, V., Tallada, J., Garges, H. P., Marongiu, A. & Borges, Á. H. & 5 flere, Jaschinski, N., Neesgaard, B., Ryom, L., Bucher, H. C. & RESPOND Study Group, 2024, I: Clinical Infectious Diseases. 78, 4, s. 995-1004 10 s.

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  11 Citationer (Scopus)

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• Risk of tuberculosis after initiation of antiretroviral therapy among persons with HIV in Europe

  Johansen, I. S., Roen, A., Kraef, C., Martín-Iguacel, R., Nemeth, J., Fenner, L., Zangerle, R., Llibre, J. M., Miller, R. F., Suarez, I., de Wit, S., Wit, F., Mussini, C., Saracino, A., Canetti, D., Volny-Anne, A., Jaschinski, N., Neesgaard, B., Ryom, L. & Peters, L. & 5 flere, Garges, H. P., Rooney, J. F., Podlekareva, D., Mocroft, A. & Kirk, O., 2024, I: International Journal of Infectious Diseases. 147, 9 s., 107199.

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• Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration

  Tusch, E., Ryom, L., Pelchen-Matthews, A., Mocroft, A., Elbirt, D., Oprea, C., Günthard, H. F., Staehelin, C., Zangerle, R., Suarez, I., Vehreschild, J. J., Wit, F., Menozzi, M., Monforte, A. D., Spagnuolo, V., Pradier, C., Carlander, C., Suanzes, P., Wasmuth, J.-C. & Carr, A. & 18 flere, Petoumenos, K., Borgans, F., Bonnet, F., De Wit, S., El-Sadr, W., Neesgaard, B., Jaschinski, N., Greenberg, L., Hosein, S. R., Gallant, J., Vannappagari, V., Young, L., Sabin, C., Lundgren, J., Peters, L., Reekie, J., D:A:D cohort study & RESPOND Cohort Collaboration, 2024, I: Clinical Infectious Diseases. 79, 5, s. 1242-1257 16 s.

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  5 Citationer (Scopus)
• 2023

  Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study

  Schwenke, J. M., Thorball, C. W., Schoepf, I. C., Ryom, L., Hasse, B., Lamy, O., Calmy, A., Wandeler, G., Marzolini, C., Kahlert, C. R., Bernasconi, E., Kouyos, R. D., Günthard, H. F., Ledergerber, B., Fellay, J., Burkhalter, F., Tarr, P. & Swiss HIV Cohort Study (SHCS), 2023, I: Journal of Infectious Diseases. 228, 6, s. 742-750 9 s.

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• Incidence and risk factors for suicide, death due to substance use, and violent/accidental death in people with HIV

  Tusch, E. S., Ryom, L., Fursa, O., Peters, L., Østergaard, L., Florence, E., Edwards, S., Hoffmann, C., Sambatakou, H., Reiss, P., Shahar, E., Reikvam, D. H., Schmied, B., Paduta, D., Yakovlev, A., Szlávik, J., Ranin, J., Zilmer, K., Uždaviniene, V. & Pelchen-Matthews, A. & 2 flere, Mocroft, A. & Reekie, J., 2023, I: AIDS. 37, 1, s. 161-171 11 s.

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  3 Citationer (Scopus)

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• Leukocyte Count and Coronary Artery Disease Events in People with Human Immunodeficiency Virus: A Longitudinal Study

  Avery, E. F., Kleynhans, J. N., Ledergerber, B., Schoepf, I. C., Thorball, C. W., Kootstra, N. A., Reiss, P., Ryom, L., Braun, D. L., Thurnheer, M. C., Marzolini, C., Seneghini, M., Bernasconi, E., Cavassini, M., Buvelot, H., Kouyos, R. D., Fellay, J., Günthard, H. F. & Tarr, P. E., 2023, I: Clinical Infectious Diseases. 76, 11, s. 1969-1979 11 s.

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  3 Citationer (Scopus)

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• Plasma Human Immunodeficiency Virus 1 RNA and CD4⁺T-Cell Counts Are Determinants of Virological Nonsuppression Outcomes with Initial Integrase Inhibitor-Based Regimens: A Prospective RESPOND Cohort Study

  Álvarez, H., Mocroft, A., Ryom, L., Neesgaard, B., Edwards, S., Svedhem, V., Günthard, H. F., Zangerle, R., Smith, C., Castagna, A., D'Arminio Monforte, A., Wit, F., Stecher, M., Lehman, C., Mussini, C., Fontas, E., González, E., Wasmuth, J. C., Sönnerborg, A. & De Wit, S. & 12 flere, Chkhartishvili, N., Stephan, C., Petoumenos, K., Jaschinski, N., Vannappagari, V., Gallant, J., Young, L., Volny Anne, A., Greenberg, L., Martín-Iguacel, R., Poveda, E. & Llibre, J. M., 2023, I: Clinical Infectious Diseases. 77, 4, s. 593-605 13 s.

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  12 Citationer (Scopus)

• Tenofovir disoproxil fumarate withdrawal and cardiovascular risk – Authors' reply

  writing group and the RESPOND study group, 2023, I: The Lancet HIV. 10, 1, s. e9-e10 2 s.

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  1 Citationer (Scopus)
• 2017

  Host Phenological Stage Potentially Affects Dieback Severity after Hymenoscyphus fraxineus Infection in Fraxinus excelsior Seedlings

  Nielsen, L. R., Mckinney, L. V. & Kjaer, E. D., 2017, I: Baltic Forestry. 23, 1, s. 229-232 4 s.

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  13 Citationer (Scopus)
• 2016

  Antiretroviral Drugs and Risk of Chronic Alanine Aminotransferase Elevation in Human Immunodeficiency Virus (HIV)-Monoinfected Persons: The Data Collection on Adverse Events of Anti-HIV Drugs Study

  Kovari, H., Sabin, C. A., Ledergerber, B., Ryom, L., Reiss, P., Law, M., Pradier, C., Dabis, F., d'Arminio Monforte, A., Smith, C., de Wit, S., Kirk, O., Lundgren, J. D. & Weber, R., 2016, I: Open Forum Infectious Diseases. 3, 1, 11 s., ofw009.

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  24 Citationer (Scopus)

  338 Downloads (Pure)

• Chronic Kidney Disease and Antiretroviral Therapy in HIV-Positive Individuals: Recent Developments

  Achhra, A. C., Nugent, M., Mocroft, A., Nielsen, L. R. & Wyatt, C. M., 2016, I: Current HIV - AIDS Reports. 13, 3, s. 149-157 9 s.

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  40 Citationer (Scopus)

• Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study

  Mocroft, A., Lundgren, J. D., Ross, M., Fux, C. A., Reiss, P., Moranne, O., Morlat, P., Monforte, A. D., Kirk, O., Ryom, L. R. & Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) Study, jan. 2016, I: The Lancet HIV. 3, 1, s. e23-32 10 s.

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  169 Citationer (Scopus)

• Essentials from the 2015 European AIDS Clinical Society (EACS) guidelines for the treatment of adult HIV-positive persons

  Nielsen, L. R., Boesecke, C., Gisler, V., Manzardo, C., Rockstroh, J. K., Puoti, M., Furrer, H., Miro, J. M., Gatell, J. M., Pozniak, A., Behrens, G., Battegay, M., Lundgren, J. D. & EACS Governing Board, feb. 2016, I: HIV Medicine. 17, 2, s. 83-8 6 s.

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  89 Citationer (Scopus)

• Improvements over time in short-term mortality following myocardial infarction in HIV-positive individuals

  Hatleberg, C. I., Nielsen, L. R., El-Sadr, W., Smith, C., Weber, R., Reiss, P., Fontas, E., Dabis, F., Law, M., Monforte, A. D., De Wit, S., Mocroft, A., Phillips, A., Lundgren, J. D., Sabin, C. & D:A:D Study Group, 19 jun. 2016, I: AIDS (London, England). 30, 10, s. 1583-1596 14 s.

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  9 Citationer (Scopus)

• Is nelfinavir exposure associated with cancer incidence in HIV-positive individuals?

  Boettiger, D. C., Sabin, C. A., Grulich, A., Nielsen, L. R., Bonnet, F., Reiss, P., Monforte, A. D., Kirk, O., Phillips, A., Bower, M., Fätkenheuer, G., Lundgren, J. D., Law, M. & Data collection on Adverse events of Anti-HIV Drugs (D:A:D) study group, 19 jun. 2016, I: AIDS. 30, 10, s. 1629-37 9 s.

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  8 Citationer (Scopus)

• Is there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with HIV? A cohort collaboration

  Sabin, C. A., Reiss, P., Ryom, L., Phillips, A. N., Weber, R., Law, M., Fontas, E., Mocroft, A., de Wit, S., Smith, C., Dabis, F., d'Arminio Monforte, A., El-Sadr, W., Lundgren, J. D. & D:A:D Study Group, 31 mar. 2016, I: BMC Medicine. 14, 14 s., 61.

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  101 Citationer (Scopus)

  145 Downloads (Pure)

• Longitudinal analysis of the associations between antiretroviral therapy, viraemia and immunosuppression with lipid levels: the D:A:D study

  Kamara, D. A., Smith, C., Ryom, L., Reiss, P., Rickenbach, M., Phillips, A., Mocroft, A., De Wit, S., Law, M., Monforte, A. D., Dabis, F., Pradier, C., Lundgren, J. D. & Sabin, C., 2016, I: Antiviral Therapy. 21, 6, s. 495-506 12 s.

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  21 Citationer (Scopus)

• Renal Impairment and Cardiovascular Disease in HIV-Positive Individuals: The D:A:D Study

  Nielsen, L. R., Lundgren, J. D., Ross, M., Kirk, O., Law, M., Morlat, P., Fontas, E., Smit, C., Fux, C. A., Hatleberg, C. I., De Wit, S., Sabin, C. A. & Mocroft, A., 15 okt. 2016, I: The Journal of Infectious Diseases. 214, 8, s. 1212-1220 9 s.

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  41 Citationer (Scopus)

• Use of antiretroviral therapy and risk of end-stage liver disease and hepatocellular carcinoma in HIV-positive persons

  Nielsen, L. R., Lundgren, J. D., De Wit, S., Kovari, H., Reiss, P., Law, M., El-Sadr, W., Monforte, A. D., Mocroft, A., Smith, C., Fontas, E., Dabis, F., Phillips, A., Sabin, C. & D:A:D Study Group, 17 jul. 2016, I: AIDS (London, England). 30, 11, s. 1731-43 13 s.

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  54 Citationer (Scopus)
• 2014

  A comparison of estimated glomerular filtration rates using Cockcroft-Gault and the Chronic Kidney Disease Epidemiology Collaboration estimating equations in HIV infection

  Mocroft, A., Nielsen, L. R., Reiss, P., Furrer, H., D'Arminio Monforte, A., Gatell, J., de Wit, S., Beniowski, M., Lundgren, J. D., Kirk, O. & EuroSIDA in EuroCoord, mar. 2014, I: HIV Medicine. 15, 3, s. 144-152 9 s.

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  25 Citationer (Scopus)

  161 Downloads (Pure)

• Antiretroviral therapy, immune suppression and renal impairment in HIV-positive persons

  Nielsen, L. R., Mocroft, A. & Lundgren, J. D., jan. 2014, I: Current Opinion in HIV and AIDS. 9, 1, s. 41-7 7 s.

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  14 Citationer (Scopus)

• Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study

  Kamara, D. A., Nielsen, L. R., Ross, M., Kirk, O., Reiss, P., Morlat, P., Moranne, O., Fux, C. A., Mocroft, A., Sabin, C., Lundgren, J. D. & Smith, C. J., 25 mar. 2014, I: B M C Nephrology. 15, 1, s. 1-13 13 s.

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  11 Citationer (Scopus)

• Predictors of advanced chronic kidney disease and end-stage renal disease in HIV-positive persons

  Nielsen, L. R., Mocroft, A., Kirk, O., Ross, M., Reiss, P., Fux, C. A., Morlat, P., Moranne, O., Smith, C., El-Sadr, W., Law, M. & Lundgren, J. D., 14 jan. 2014, I: AIDS (London, England). 28, 2, s. 187-199 13 s.

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  61 Citationer (Scopus)

• Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration

  Smith, C. J., Nielsen, L. R., Weber, R., Morlat, P., Pradier, C., Reiss, P., Kowalska, J. D., de Wit, S., Law, M., el Sadr, W., Kirk, O., Friis-Moller, N., Monforte, A. D., Phillips, A. N., Sabin, C. A., Lundgren, J. D. & D:A:D Study Group, 19 jul. 2014, I: Lancet. 384, 9939, s. 241-248 8 s.

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  795 Citationer (Scopus)
• 2013

  Advanced chronic kidney disease, end-stage renal disease and renal death among HIV-positive individuals in Europe

  Nielsen, L. R., Kirk, O., Lundgren, J. D., Reiss, P., Pedersen, C., De Wit, S., Buzunova, S., Gasiorowski, J., Gatell, J. M., Mocroft, A. & EuroSIDA in EuroCoord, sep. 2013, I: HIV Medicine. 14, 8, s. 503-8 6 s.

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  38 Citationer (Scopus)

• Antiretroviral drug-related liver mortality among HIV-positive persons in the absence of hepatitis B or C virus coinfection: the data collection on adverse events of anti-HIV drugs study

  Kovari, H., Sabin, C. A., Ledergerber, B., Nielsen, L. R., Worm, S. W., Smith, C., Phillips, A., Reiss, P., Fontas, E., Petoumenos, K., De Wit, S., Morlat, P., Lundgren, J. D. & Weber, R., mar. 2013, I: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 56, 6, s. 870-9 10 s.

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  40 Citationer (Scopus)

• Association between antiretroviral exposure and renal impairment among HIV-positive persons with normal baseline renal function: The D:A:D Study

  Nielsen, L. R., Mocroft, A., Kirk, O., Worm, S. W., Kamara, D. A., Reiss, P., Ross, M., Fux, C. A., Morlat, P., Moranne, O., Smith, C. B. & Lundgren, J. D., 1 maj 2013, I: The Journal of Infectious Diseases. 207, 9, s. 1359-69 11 s.

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  270 Citationer (Scopus)

• Associations between immune depression and cardiovascular events in HIV infection

  Sabin, C. A., Nielsen, L. R., De Wit, S., Mocroft, A., Phillips, A. N., Worm, S. W., Weber, R., D'Arminio Monforte, A., Reiss, P., Kamara, D., El-Sadr, W., Pradier, C., Dabis, F., Law, M. & Lundgren, J., 6 aug. 2013, I: AIDS (London, England).

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  53 Citationer (Scopus)

• Atazanavir is not associated with an increased risk of cardio- or cerebrovascular disease events

  Monforte, A. D., Reiss, P., Nielsen, L. R., El-Sadr, W., Dabis, F., De Wit, S., Worm, S. W., Law, M. G., Weber, R., Kirk, O., Pradier, C., Phillips, A. N., Lundgren, J. D. & Sabin, C. A., 28 jan. 2013, I: AIDS (London, England). 27, 3, s. 407-15 9 s.

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  89 Citationer (Scopus)

• Chronic Kidney Disease in HIV-Positive Persons; Contribution of Traditional Risk Factors, HIV and Antiretrovial Agents.

  Nielsen, L. R., 2013, Eget forlag. 60 s.

  Publikation: Bog/antologi/afhandling/rapport › Ph.d.-afhandling
• 2012

  Kidney failure related to broad-spectrum antibiotics in critically ill patients: secondary end point results from a 1200 patient randomised trial

  Jensen, J.-U. S., Hein, L., Lundgren, B., Bestle, M. H., Mohr, T., Andersen, M. H., Thornberg, K. J., Løken, J., Steensen, M., Fox, Z., Tousi, H., Søe-Jensen, P., Lauritsen, A. Ø., Strange, D. G., Reiter, N., Thormar, K., Fjeldborg, P. C., Larsen, K. M., Drenck, N.-E. & Johansen, M. E. & 6 flere, Nielsen, L. R., Ostergaard, C., Kjær, J., Grarup, J., Lundgren, J. D. & Procalcitonin And Survival Study (PASS) Group, 2012, I: B M J Open. 2, 2, s. e000635

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  72 Citationer (Scopus)