Billede af Louise von Gersdorff Jørgensen
  • Kilde: Scopus
20052024

Publikationer pr. år

Personlig profil

Kort præsentation

I primarily work on the fish immune system in rainbow trout and zebrafish (www.zebrafish.ku.dk). My focus is on immunology, vaccinology, aquaculture, disease modelling, imaging, molecular biology, the CRISPR/Cas9 technique, parasitology and bacteriology. I have for many years worked with a parasitic disease, called white spot disease, caused by a protozoan Ichthyophthirius multifiliis and continuously investigate new opportunities within vaccine development as well as working on the host/parasite interactions primarily focusing on the immune responses of the hosts. Zebrafish are also used in our group for real-time in vivo imaging of immunological responses against virus, bacteria and parasites.

I am a biologist from the University of Copenhagen and have been working with the fish immune system and aquaculture since November 2005. I got my PhD degree in 2011 and since the summer 2018 have been working as Associate Professor in the department.

CV

Education

2019: Leading research – leadership course, University of Copenhagen

2014: (Pre-) leader course "women, career and UCPH", University of Copenhagen

2012-2014: Course "Teaching and Learning in Higher Education", University of Copenhagen

2007-2011: PhD degree at the Laboratory of Aquatic Pathobiology, University of Copenhagen. Title “Immunity against Ichthyophthirius multifiliis in rainbow trout”. Main supervisor, Professor Kurt Buchmann. Degree obtained the 1st of November 2011.

2003: Master of Science degree in Biology, Mandahl-Barth Research Center for Biodiversity and Health, DBL - Institute for Health Research and Development. Supervisor, Professor Thomas Krogsgaard Kristensen

Professional experience                                                                            

2018-now: Associate professor at the Laboratory of Aquatic Pathobiology, University of Copenhagen

2015-2018: Assistant professor at the Laboratory of Aquatic Pathobiology, University of Copenhagen

2012-2015: Postdoc at the Laboratory of Aquatic Pathobiology, University of Copenhagen.

2005-2007 & 2011-2012: Scientific Research assistant at the Laboratory of Aquatic Pathobiology, University of Copenhagen               

Research related stays abroad

2013May-July, research stay in Professor Oriol Sunyers laboratory at the University of Pennsylvania in Philadelphia. Result: one paper published in Nature communications.

Grants 

2021: DFF – Technology and Production. Identifying genes responsible for natural resistance against a fish parasite. 2.88 M DKK.

2021: Horizon 2020 network grant: RASOPTA - Safeguarding future production of fish in aquaculture systems with water recirculation. 24 M DKK. I am coordinator and work package lead.

2021: GUDP grant: Profishence 7 M DKK. PI Anders Miki Boyesen.

2020: Carlsbergfondet. Infrastructure grant: 240.000 DKK for a new fluorescence stereo microscope for zebrafish teaching and research

2019: DFF – Danish ERC programme. HOSTgutINTERACT – PI Morten Limborg, Globe Institute, University of Copenhagen. 500.000 DKK for my group for the implementation of the CRISPR/Cas9 technique in zebrafish.

2018: Kirsten & Freddy Johansens Fond for the project “In vivo visualisering af immunrespons og infektionsmønster af rhabdovirus” – in zebrafish (103.000 DKK).                                                                                                 

2012-2016: Postdoc funding: The Danish Council for Independent Research – Technology and Production Sciences (3,205,315 DKK, $577.701). Title “A novel anti-parasitic vaccine using killed bacterial vectors for the introduction of parasite antigens in fish”, which resulted in 5 published peer review papers and one patent.

Patents

2016: Title: Vaccination targeting Ichthyophthirius multifiliis. Reference number: 20824EP00. I am co-inventor of this invention disclosed in a priority founding European patent application filed on 17 June 2016 by Evaxion Biotech ApS.

Scientific focus areas

  • Fish (rainbow trout and zebrafish, zebrafish.ku.dk) and parasitology
  • Immunology, fish diseases and diagnosis
  • Biotechnology (e.g. CRISPR/Cas 9 gene mutation technique) and vaccinology
  • In vivo imaging (confocal microscopy)

International relations

As coordinator of RASOPTA (www.rasopta.ku.dk ) and participation in international projects such as Imaquanim (http://tinyurl.com/hwfxfk8), TargetFish (http://targetfish.eu) and Parafish Control (http://www.parafishcontrol.eu) I have built a wide international network. These collaborations have resulted in substantial scientific results and provide the basis for future projects. I am a member of the International Society of Fish and Shellfish Immunology (ISFSI) board as secretary treasurer.

2021, March: I held an international webinar for WAVMA and EAFP (World Aquatic Veterinary Medical Association and European Association of Fish Pathologists with 413 registered international participants. Title: zebrafish as a model for fish diseases.

Supervision

2021-24: Principal supervisor for two PhD students enrolled in the graduate programme Immunology and Infectious Diseases

2016-22: Co-supervisor for three PhD students currently enrolled in the graduate programme Immunology and Infectious Diseases.

2017-2018: I co-supervised a master student Anna Magdalene Brun on the thesis: The aquatic toxicology and endocrine disrupting potential of nitrification inhibitors (in zebrafish). She is now doing a PhD project at the University of Aarhus.

2016-17: Co-supervisor for a veterinary master student Therese Birgitte Christoffersen, thesis: Immunrespons mod Ichthyophthirius multifiliis infektion i zebrafisk (Danio rerio) – vurderet ved qPCR og histologi.

2015-16: Main supervisor for a veterinary master student (Sandra Jeberg) and of a master of parasitology student (Jonas Sørensen).

Committee work

Member of PhD evaluation committees; University of Tasmania (2015, 2019), Australia, University of Bergen (2020), Norway, Technical University of Denmark (2021), Ben Gurion University, Israel (2021), University of Copenhagen, Denmark (2021).

Publications                                                                                                                                                                                   

43 Peer review publications (Journal of Hazardous Materials, PNAS, Nature Communications)

33 Conference abstracts

6 Invited talks

 

h-index 15

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