Publikationer pr. år
Publikationer pr. år
Bartholinsgade 6Q, 2. sal, 1356 København K, 24 Øster Farimagsgade 5, 24-2-23
Øster Farimagsgade 5 opg. B
1415 København K
Publikationer pr. år
Name: Marie Pedersen
Date of birth: November 24, 1978
Nationality: Danish
EDUCATION
2007-2010: PhD, University of Copenhagen, Department of Public Heath, Section of Environmental Health, Copenhagen, Denmark. Title: ‘Transplacental exposure to environmental pollutants: Biomarkers of exposures and effects in blood from mother-newborn pairs.’ Main advisor Professor Lisbeth E. Knudsen, Co-advisor Professor Steffen Loft.
2003-2005: MSc in Biology received on May 10, 2005, University of Copenhagen, Department of Biology, Copenhagen, Denmark.
2000-2003: BA in Biology received on January 1, 2003, University of Copenhagen, Department of Biology, Copenhagen, Denmark.
CURRENT AND MOST RECENT POSITIONS
2015-now: Associate Professor, Section of Epidemiology, Department of Public Health, University of Copenhagen.
2020-now: Researcher, Statens Serum Insitut, Epidemiology, Copenhagen, Denmark.
2014-2019: Researcher, Danish Cancer Society Research Center, Diet, Genes and Environment, Copenhagen, Denmark.
2010-2014: Postdoctoral Research Fellow, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain and National Institute of Health and Medical Research (INSERM), Environmental Epidemiology Applied to Reproduction and Respiratory Health, Grenoble, France.
2004-2007: Research Assistant, Section of Environmental Health, Department of Public Heath, University of Copenhagen, Copenhagen, Denmark.
2004: Student intern, International Symposium on Uncertainty and Precaution in Environmental Management, Technical University of Denmark and The European Environmental Agency, Copenhagen, Denmark.
2002-2005: Student intern, The Danish Ministry of the Environment, Copenhagen, Denmark.
ACADEMIC AWARDS AND HONOURS
FUNDED COMPETITIVE RESEARCH GRANTS
2020: Marie Curie postdoc grant for Tim Cadman (my role: mentor), EU
2020: Research exchange stay support for Tim Cadman (my role: mentor), Lifecycle, EU
2020: Research support for Vanessa Coffmann (my role: mentor), NIH, US
2017: ERC Starting grant, European Research Council, Bruxelles, Belgium
2017: Walter A. Rosenblith New Investigator Award, the Health Effects Institute, Boston, Ma, US
2014: Research Fellowship, the Danish Council for Independent Research, the Danish Ministry of Higher Education and Science, Copenhagen, Denmark
2014: Travel Grant, CREAL, Barcelona, Spain
2013: Travel Grants, CREAL, Barcelona, Spain
2012: Travel Grant, CREAL, Barcelona, Spain
2011: Post-Doctoral Fellowship (full salary and costs, 3 years), Juan de la Cierva, the Spanish Ministry of Science and Innovation, Madrid, Spain.
2006: PhD Scholarship (full academic, 3 years), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
2005: Grant to buy a microscope, the Danish Test Animal Protection (Forsøgsdyrenes Værn)
2005: Exchange Fellowship to cover costs of genome-wide transcriptomic analyses, salary and 3-months stay in Maastricht, Netherlands, ECNIS (Environmental Cancer Risk, Nutrition and Individual Susceptibility)
INTERNATIONAL AND NATIONAL RELATIONS
COMMISSIONS OF TRUSTS
TEACHING
MEMBERSHIPS OF SCIENTITIC SOCIETIES
2006-now: The International Society for Environmental Epidemiology (ISEE): https://www.iseepi.org
2005-now: European Environmental Mutagen Genomic Society (EEMGS): https://www.eemgs.eu
2015-now: Dansk Epidemiologisk Selskab (DES): https://www.dansk-epidemiologisk-selskab.dk
MANAGEMENT EXPERIENCE
2020-now: PI of studies of health effects of living near animal farms
2017-now: PI of prospective biomarker-based studies to evaluate effects of prenatal exposure to dietary acrylamide as part of CHIPS (Children's Health in relation to Intrauterine Exposure to Heat-Generated Pollutants)
2017-now: PI of epidemiological studies on ambient air pollution and health of children and pregnant women
2014-2017: Coordination of pooling of cohort-specific results for a meta-analyses on cancer in bladder, liver and kidney as part of the ESCAPE (www.escapeproject.eu).
2011-2017: Coordinated the collection, harmonization, pooling and analyses of data on air pollution, birth outcomes, postnatal growth and personal characteristics from women participating in 14 European birth cohorts as part of the ESCAPE (www.escapeproject.eu).
2010-2015: Coordinated the collection, harmonization, pooling and analyses of data on biomarkers, birth outcomes, diet and personal characteristics from women participating in 5 European birth cohorts as part of the NewGeneris (http://www.newgeneris.org).
2007-2010: Coordinated the collection, processing and analyses of questionnaires, air, dust, urine, blood and placenta samples from 250 women as part of my PhD. Recruited and interviewed the participants.
RESEARCH PROJECTS
ADDITIONAL EXTERNAL COURSES
2020: Data safety
2017: ERC StG Interview Training
2016: University Peadagogy
2015: Supervision of master students, Copenhagen, Denmark.
2015: Livable Future Cities, edx.
2015: Responsible Conduct of Research, Copenhagen, Denmark.
2015: R – an introduction, Copenhagen, Denmark.
2015: The Successful ERC Applicant, Copenhagen, Denmark.
2014: Occupational Hazards and Reproductive Health, NIVA, Espoo, Finland.
2013: European Educational Programme in Epidemiology, Florence, Italy.
2012: Leading for Success in Science, Team Leadership & Management Skills, Spain.
2011: Principles of Genetic Association Studies, University Pompeu Fabra, Spain.
2009: Critical Windows of Exposures and Vulnerability, Paris, France.
2008: Paediatric Research, School of Health Sciences, Copenhagen, Denmark.
2008: Practical oral communication, University of Southern Denmark, Odense, Denmark.
2006: Use of SAS Statistical Software, Biostatistics, University of Copenhagen, Denmark.
2006: Toxicogenomics, TNO, Maastricht University, Maastricht, The Netherlands.
2006: Molecular Nutrition in Relation to Cancer Res., Karolinska Institute, Sweden.
2006: Nutritional Epidemiology, Preventive Medicine, University of Copenhagen, Denmark.
2006: Gene-Environment Interactions, Karolinska Institute, Stockholm, Sweden.
2005: Health: Individual and Environment, University of Copenhagen, Denmark.
2005: Applied Toxicology, National University Hospital, Copenhagen, Denmark.
2004: Environmental Multidiscipline, University of Aarhus, Aarhus, Denmark.
2003: Epidemiology, Medicine, University of Copenhagen, Denmark.
2003: Environmental Management and Ethics, Technical University of Denmark.
2003: Practical Application of Environmental Principles, Technical University of Denmark.
PEER-REVIEWED PUBLICATIONS, BOOK CHAPTERS AND NON-PEER REVIEWED PUBLICATIONS
Please see: http://orcid.org/0000-0002-9930-0446
Marie's research focuses on the evaluation of effects of environmental exposures early in life. Currently she is involved in Danish as well as European birth cohort studies that examine the influence of exposure to dietary and environmental toxicants during pregnancy on maternal and child health.
Marie has a degree in Biology from the University of Copenhagen, Denmark and a PhD at the Department of Public Health, University of Copenhagen, Denmark (2010). Marie did her postdoctoral work at the Centre for Research in Environmental Epidemiology, Barcelona, Spain and in the Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, National Institute of Health and Medical Research (INSERM), Grenoble, France (2010-2014). Afterwards she worked as researcher at the Danish Cancer Society Research Center, Diet, Genes and Environment, Copenhagen, Denmark (2014-2018). In 2015 Marie started as associate professor at the Department of Public Health, University of Copenhagen.
Acrylamide
Acrylamide is a chemical formed in many commonly consumed foods and beverages. It is neurotoxic, crosses the placenta and has been associated with restriction of fetal growth in humans. In animals, acrylamide causes heritable mutations, tumors, developmental toxicity, reduced fertility and impaired growth. Therefore, the discovery of acrylamide in food in 2002 raised concern about human health effects worldwide. Still, epidemiological studies are limited and effects on health of prenatal exposure have never been evaluated. Epidemiological studies have mostly addressed exposure during adulthood, focused on cancer risk in adults, and relied on questionnaires entailing a high degree of exposure misclassification. Biomarker studies on prenatal exposure to acrylamide from diet are critically needed to improve exposure assessment and to determine whether acrylamide leads to major diseases later in life.
The aim of CHIPS (Children’s Health in Relation to Intrauterine Exposure to Heat-Generated Pollutants) is to determine the effects of prenatal exposure to acrylamide alone and in combination with other potentially toxic adduct-forming exposures on the health of children and young adults. Both well-established and innovative biomarker methods will be used for characterization of prenatal exposure to acrylamide and related toxicants in blood from pregnant women and their offspring in prospective cohort studies with long-term follow-up. Risk of neurological disorders, impaired cognition, disturbed reproductive function and metabolic outcomes such as obesity and diabetes will be evaluated.
This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 758151).
Air pollution and asthma
Asthma is the most common chronic disease in children. There is growing experimental and epidemiological evidence that exposure to ambient air pollution from combustion such as motor vehicle emissions not only exacerbates existing asthma, but also contributes to the development of asthma. Asthma has a complex multifactorial etiology, which is still not fully understood, as multiple factors starting from fetal life, may interact.
The aim of this research is to examine the individual and joint effects of early-life exposure to air pollution from multiple outdoor and indoor sources on risk of development of asthma in children and adolescents. Furthermore, we seek to determine the mechanistic basis for these effects by studying changes in lung function, inflammation, immunological markers and airway DNA methylation.
Individual health, home, home neighborhood and personal characteristics from national registers will be used for prospective studies of all children and adolescents born in Denmark since 1997 together with detailed questionnaire data from the Danish National Birth Cohort (DNBC) and repeated measurements of lung function and biomarkers from the COPenhagen Prospective Studies on Asthma in Childhood (COPSAC). Early-life exposure to outdoor air pollution to a wide range of air pollutants will be estimated at home addresses with validated and novel prediction models. Register and questionnaire data on asthma incidence from birth to 18 years of age, home characteristics, home neighborhood will be evaluated. Confounding and effect modification by personal characteristics and exposures will be considered.
The research described above is being conducted under contract to the Health Effects Institute (HEI), an organization jointly funded by the United States Environmental Protection Agency (EPA) (Assistance Award No. CR-83590201) and certain motor vehicle and engine manufacturers. The contents of this research do not necessarily reflect the views of HEI, or its sponsors, nor do they necessarily reflect the views and policies of the EPA or motor vehicle and engine manufacturers.
National and International Collaboration
Biologi, Ph.d., Københavns Universitet
1 nov. 2007 → 31 mar. 2010
Dimissionsdato: 7 aug. 2010
Statens Serum Institut
1 jun. 2020 → …
Kræftens bekæmpelse, Kost, gener og miljø
1 nov. 2014 → 1 sep. 2019
Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain
1 apr. 2010 → 31 okt. 2014
National Institute of Health and Medical Research (INSERM), Environmental Epidemiology Applied to Reproduction and Respiratory Health, Grenoble, France
1 apr. 2010 → 31 okt. 2014
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review