Ole Jannik Bjerrum

Søgeresultater

• 2022

  Dorsal horn volume loss and pain pathway changes in Cavalier King Charles Spaniels with syringomyelia, signs of pain, and phantom scratching

  Mortensen, D., Thoefner, M. S., Agerholm, J. S., Slumstrup, L., Jensen, T. S., Bjerrum, O. J., Berendt, M. & Nyengaard, J. R., 2022, I: Pain. 163, 12, s. 2365-2379

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  4 Citationer (Scopus)
• 2020

  Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA's and FDA's Views on Initial Dual-Therapy

  Bjerrum, O. J., Eichendorff, S. & Alkis, N. B., mar. 2020, I: Therapeutic Innovation & Regulatory Science. 54, 2, s. 297-302 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  1 Citationer (Scopus)

• Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

  Nøhr-Nielsen, A., Lange, T., Forman, J. L., Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, O. J. & Lund, T. M., 2020, I: The AAPS Journal. 22, 2, 32.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  2 Citationer (Scopus)

• Pregabalin alleviates clinical signs of syringomyelia-related central neuropathic pain in Cavalier King Charles Spaniel dogs: a randomized controlled trial

  Thoefner, M. S., Skovgaard, L. T., McEvoy, F. J., Berendt, M. & Bjerrum, O. J., 2020, I: Veterinary Anaesthesia and Analgesia. 47, 2, s. 238–248

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  8 Citationer (Scopus)

  245 Downloads (Pure)
• 2019

  Analysis of the Authorized Target Populations for Fixed Dose Combination Products Between 2000 and 2017 Reveals Discrepancies Between EMA’s and FDA’s Views on Initial Dual-Therapy

  Bjerrum, O. J., Eichendorff, S. & Alkis, N. B., 2019, I: Therapeutic Innovation & Regulatory Science. 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

  Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, T., Bjerrum, O. J. & Lund, T. M., 2019, I: British Journal of Clinical Pharmacology. 85, 8, s. 1829-1840 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  6 Citationer (Scopus)

• Community pharmacies as platform for collection of real-world evidence of medicines usage explored through a pilot study: From standard T2D medication to treatment with the injectable combination product Xultophy

  Alkis, N., Nørgaard, L. S. & Bjerrum, O. J., 2019.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Glutamate transport system as a key constituent of glutamosome: Molecular pathology and pharmacological modulation in chronic pain

  Gegelashvili, G. & Bjerrum, O. J., 2019, I: Neuropharmacology. 161, 107623.

  Publikation: Bidrag til tidsskrift › Review › Forskning › peer review
  32 Citationer (Scopus)

• Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs

  Thoefner, M. S., Westrup, U., Toft, N., Bjerrum, O. J. & Berendt, M., 2019, I: Veterinary Journal. 246, s. 92-97 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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  8 Citationer (Scopus)

  37 Downloads (Pure)
• 2018

  Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

  Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, O. J., Dupontd, E., Nachman, G., Lykkesfeldt, J., Jensen, T. S. & Møller, L. B., 2018, I: Pain. 159, 6, s. 1012-1024 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  5 Citationer (Scopus)

• Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine

  Bjerrum, O. J. & Androlyte, M., aug. 2018, I: Basic & Clinical Pharmacology & Toxicology. 123 , 2, s. 155–160 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  5 Citationer (Scopus)

• The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain

  Kristensen, P. J., Gegelashvili, G., Munro, G., Heegaard, A. M. & Bjerrum, O. J., feb. 2018, I: European Journal of Pain. 22, 2, s. 282-294

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  11 Citationer (Scopus)
• 2017

  From Face-to-fase training to blended learning in the postgraduate program SafeSciMet - a case study

  Bjerrum, O. J., Vos, C., Dragovic, S., Jochimsen, M., Dirac, J., Foth, H. & Wiese, J., 2017, I: European Journal of Pharmaceutical Sciences. 96, s. III-VIII 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

• Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain: Molecular Mechanisms and Pharmacology

  Gegelashvili, G. & Bjerrum, O. J., 2017, Glial Amino Acid Transporters. Springer, Bind 16. s. 225-253 29 s. (Advances in Neurobiology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review
  16 Citationer (Scopus)

• Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

  Kristensen, P. J., Heegaard, A. M., Kristensen, S. H., Jeggo, R. D., Bjerrum, O. J. & Munro, G., apr. 2017, I: European Journal of Pain. 21, 4, s. 692-704 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  16 Citationer (Scopus)
• 2016

  A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science: Workshop Proceedings and Commentary

  Borup, G., Bach, K. F., Schmiegelow, M., Kildemoes, H. W., Bjerrum, O. J. & Westergaard, N., maj 2016, I: Therapeutic Innovation & Regulatory Science. 50, 3, s. 304-311 8 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review
  19 Citationer (Scopus)
• 2015

  An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition

  Sawicki-Wrzask, D., Thomsen, M. & Bjerrum, O. J., 2015, I: Therapeutic Innovation & Regulatory Science. 49, 4, s. 553-559 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  10 Citationer (Scopus)

• Intraplantar injection of tetrahydrobiopterin induces nociception in mice

  Bidragets oversatte titel: Intraplantar injektion af tetrahydrobiopterin fremkalder nociception i musNasser, A., Ali, S., Wilsbech, S., Bjerrum, O. J. & Birk Møller, L., 2015, I: Neuroscience Letters. 584, s. 247-252 6 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  10 Citationer (Scopus)

• The wider use of fixed-dose combinations emphasizes the need for a global approach to regulatory guideline development

  Gautam, Y., Bjerrum, O. J. & Schmiegelow, M., 2015, I: Therapeutic Innovation & Regulatory Science. 49, 1, s. 197-204 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  5 Citationer (Scopus)
• 2014

  Drug-drug combinations revisited

  Bjerrum, O. J., Gautam, Y., Honoré, P. G. H. & Vana, V., 15 jan. 2014, I: European Journal of Hospital Pharmacy - Science and Practice. 21, 1, s. 8-12 5 s.

  Publikation: Bidrag til tidsskrift › Review › Forskning › peer review
  5 Citationer (Scopus)

• High-affinity glutamate transporters in chronic pain: an emerging therapeutic target

  Gegelashvili, G. & Bjerrum, O. J., 2014, I: Progress in Neurobiology. 131, 6, s. 712-730

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  42 Citationer (Scopus)
• 2013

  Donepezil anvendt ved neuropatisk smerte

  Bjerrum, O. J. & Bjerrum, H. J., 2013, I: Ugesskrift for læger. 175, 42, s. 2493-2494 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  1 Citationer (Scopus)

• Donepezil as add-on to gabapentin for post-traumatic neuropathic pain: an exploratory study

  Basnet, A., Butler, S., Honoré, P. G. H., Butler, M., Gordh, T. E., Kristensen, K. K. & Bjerrum, O. J., 2013, I: Acta Anaesthesiologica Scandinavica. 58, 1, s. 61-73 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  15 Citationer (Scopus)

• Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCi-operated rats

  Bjerrum, O. J., Honoré, P. G. H., Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Gegelashvili, G., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Dose-dependent effect of ceftriaxone (A beta-lactam) on mechanical pain hypersensitivity in the CCI nerve rat model

  Bjerrum, O. J., Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Honoré, P. G. H., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Fixed Dose Combinations. The Physician attitude to the wider use. A pilot study

  Bjerrum, O. J. & Vana, V., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Fixed drug combinations: are current regulatory guidelines in the EU and US adequate for effectively guiding Development?

  Bjerrum, O. J., Gautam, Y. & Schmiegelow, M., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain

  Nasser, A., Bjerrum, O. J., Heegaard, A-M., Møller, A. T., Larsen, M., Dalbøge, L. S., Dupont, E., Jensen, T. S. & Møller, L. B., 19 feb. 2013, I: Molecular Pain. 9, s. 5

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  21 Citationer (Scopus)

• Measurement of sedation in rats. Comparison of the locomotor activity test, open field test and the rotarod test

  Bjerrum, O. J., Nasser, A., Basnet, A., Merry, A. & Kristensen, P., nov. 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Medicines combinations options and regulatory hurdles

  Bjerrum, O. J., Gautam, Y., Bjerrum, E. J., Schmiegelow, M. & Boonen, H. C. M., 16 jul. 2013, I: European Journal of Pharmaceutical Sciences. 49, 4, s. 659-63 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  10 Citationer (Scopus)

• Orphan disease council - A new interdiciplinary private/public partnership promoting the Development of orphan medicinal products

  Bjerrum, O. J., Hove, H. B., Dali, C., Callesen, L., Ludvig, G. & Thyregod, L., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Pain perception and Dopa Responsive Dystonia

  Bjerrum, O. J., Nasser, A., Møller, A. T., Møller, B. & Jensen, T. S., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Promising effects of donepezil when added to patients treated with gabapentin for neuropathic pain

  Basnet, A., Butler, S., Honoré, P. G. H., Butler, M., Gordh, T. E., Kristensen, K. & Bjerrum, O. J., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Why medicines Combinations? Friend or Foe?

  Bjerrum, O. J., Gautam, Y., Boonen, H. C. M., Schmiegelow, M. & Honoré, P. G. H., 2013.

  Publikation: Konferencebidrag › Poster › Forskning › peer review
• 2012

  Blå medicin mod smerter

  Boulakou, A., Bjerrum, O. J. & Honoré, P. G. H., 2012, I: Lægemiddelforskning. 2012, s. 18-19 2 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Formidling

• Kombinationslægemiddel reducerer bivirkningerne ved smertebehandling

  Bjerrum, O. J., Basnet, A., Honoré, P. G. H. & Gautam, Y., 2012, I: Lægemiddelforskning. 1, s. 15-17 3 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Formidling

• Sortilins in neuropathic pain

  Richner, M., Bjerrum, O. J., Koninck, Y. D., Nykjaer, A. & Vaegter, C. B., 29 dec. 2012, I: Scandinavian Journal of Pain. 3, 3, s. 183-184 2 s.

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning
• 2011

  Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2

  Bjerrum, O. J., Abrahamsen, B. & Honoré, P. G. H., nov. 2011.

  Publikation: Konferencebidrag › Poster › Formidling

• Beta-lactam antibiotic as dose dependent analgesic treatment of neuropathic pain

  Bjerrum, O. J., Abrahamsen, B. & Honoré, P. G. H., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Ceftriaxone, an EAAT-2 transporter inducer, shows antinociceptive effects in acute and neuropathic pain models

  Bjerrum, O. J., Abrahamsen, B. & Honoré, P. G. H., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Characterization of drug combination effects in a rat model of neuropathic pain ny population modelling and simulation of response-time profiles

  Bjerrum, O. J. & Honoré, P. G. H., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Combination therapy for neuropathic pain: Donepezil improves gabapentins antinoceptive effect in SNI rats

  Bjerrum, O. J. & Honoré, P. G. H., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

  Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, O. J., Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 apr. 2011, I: European Journal of Pharmaceutical Sciences. 43, 3, s. 141-150 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  52 Citationer (Scopus)

• Decrease in nocifensive behaviour in rats after treatment with the EAAT-2 transporter inducer cetriaxone

  Bjerrum, O. J., Honoré, P. G. H. & Abrahamsen, B., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Development of quantitative Pharmacology Pharmacometrics in Denmark

  Bjerrum, O. J. & Honoré, P. G. H., 2011.

  Publikation: Konferencebidrag › Poster › Forskning › peer review

• Development of quantitative pharmacology-pharmacometrics in Denmark

  Honoré, P. G. H., Bjerrum, O. J., Lund, T. M., Angelo, H., Ingwersen, S. H., Thygesen, P., Kristensen, K. & Larsen, F., 2011.

  Publikation: Konferencebidrag › Poster › Forskning

• Effects of the excitatory amino acid transporter subtype 2(EAAT-2) inducer ceftriaxone on different pain modalities in rat

  Eljaja, L., Bjerrum, O. J., Honoré, P. G. H. & Abrahamsen, B., 2011, I: Scandinavian Journal of Pain. 2, 3, s. 132-136 4 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
  14 Citationer (Scopus)

• European new safe and innovative medicines initiatives: history and progress (through December 2009)

  Bjerrum, O. J. & H. Linden, H., mar. 2011, Translational medicine and drug discovery. Cambridge: Cambridge University Press, s. 265-288 23 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Formidling

  6 Citationer (Scopus)

• Excellence in education and training advances competitiveness of the pharmaceutical industry in Europe

  Bjerrum, O. J., 2011, I: European Journal of Pharmaceutical Sciences. 44, 2, s. 174-175 2 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning
  2 Citationer (Scopus)

• Neuropathic pain models in the development of analgesic drugs

  Honoré, P. G. H., Basnet, A., Eljaja, L., Kristensen, P., Neustrup, L. M., Møllgaard, P. & Bjerrum, O. J., 2011, I: Scandinavian Journal of Pain. 2, 4, s. 172-177 5 s.

  Publikation: Bidrag til tidsskrift › Review › Forskning › peer review
  16 Citationer (Scopus)