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Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 flere, Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, L., Coelho, L. P., Rouault, C., Gauguier, D., Gøtze, J. P., Prifti, E., Froguel, P., Alili, R., Galijatovic, E. A. A., Barthelemy, O., Bastard, J. P., Batisse, J. P., Bel-Lassen, P., Berland, M., Bittar, R., Blottière, H., Bosquet, F., Boubrit, R., Bourron, O., Camus, M., Ciangura, C., Collet, J. P., Dietrich, A., Djebbar, M., Doré, A., Engelbrechtsen, L., Fezeu, L., Fromentin, S., Pons, N., Graine, M., Grünemann, C., Hartemann, A., Hartmann, B., Hornbak, M., Jaqueminet, S., Jørgensen, N. R., Julienne, H., Justesen, J., Kammer, J., Karup, N., Kozlowski, R., Kuhn, M., Lejard, V., Letunic, I., Levenez, F., Marko, L., Martinez-Gili, L., Massey, R., Maziers, N., Moitinho-Silva, L., Montalescot, G., Neves, A. L., Le Pavin, L. P., Pousset, F., Rodriguez-Martinez, A., Schmidt, S., Schütz, T., Silva, L., Silvain, J., Svendstrup, M., Swartz, T. D., Vanduyvenboden, T., Verger, E. O., Walther, S., Zucker, J. D., Bäckhed, F., Vestergaard, H., Hansen, T., Oppert, J. M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M. M., Stumvoll, M., Pedersen, O., Ehrlich, S. D., Clément, K. & Dumas, M. E., 2023, I: Nature Communications. 14, 18 s., 5843.

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Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 flere, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, K. D., Vangipurapu, J., Vestergaard, H., Brunak, S., Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, O., Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, M., Atabaki-Pasdar, N., Baltauss, T., Banasik, K., Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., Engelbrechtsen, L., Eriksen, R., Fan, Y., Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, U. P., Jennison, C., Johansen, J., Jonsson, A., Karaderi, T., Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, A. T. T., Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, S., Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, C. E. E., Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 2023, I: Nature Communications. 14, 17 s., 5062.

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6 Citationer (Scopus)

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Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents

Ullah, A., Stankevic, E., Holm, L. A., Stinson, S. E., Juel, H. B., Fonvig, C. E., Lund, M. A. V., Trier, C., Engelbrechtsen, L., Ängquist, L., Jonsson, A. E., Pedersen, O., Grarup, N., Holm, J. C. & Hansen, T., 2023, I: Antioxidants. 12, 8, 1613.

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3 Citationer (Scopus)

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Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 flere, Allard, C., Groleau, M., Kuulasmaa, T., Leirer, D. J., White, F., Jacques, P. É., Cheng, H., Hao, K., Andreassen, O. A., Åsvold, B. O., Atalay, M., Bhatta, L., Bouchard, L., Brumpton, B. M., Brunak, S., Bybjerg-Grauholm, J., Ebbing, C., Elliott, P., Engelbrechtsen, L., Erikstrup, C., Estarlich, M., Franks, S., Gaillard, R., Geller, F., Grove, J., Hougaard, D. M., Kajantie, E., Morgen, C. S., Nohr, E. A., Nyegaard, M., Palmer, C. N. A., Pedersen, O. B., Rivadeneira, F., Sebert, S., Shields, B. M., Stoltenberg, C., Surakka, I., Thørner, L. W., Ullum, H., Vaarasmaki, M., Vilhjalmsson, B. J., Willer, C. J., Lakka, T. A., Gybel-Brask, D., Bustamante, M., Hansen, T., Pearson, E. R., Reynolds, R. M., Ostrowski, S. R., Pennell, C. E., Jaddoe, V. W. V., Felix, J. F., Hattersley, A. T., Melbye, M., Lawlor, D. A., Hveem, K., Werge, T., Nielsen, H. S., Magnus, P., Evans, D. M., Jacobsson, B., Järvelin, M. R., Zhang, G., Hivert, M. F., Johansson, S., Freathy, R. M., Feenstra, B. & Njølstad, P. R., 2023, I: Nature Genetics. 55, 11, s. 1807-1819 13 s.

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The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

Reim, P. K., Engelbrechtsen, L., Gybel-Brask, D., Schnurr, T. M., Kelstrup, L., Høgdall, E. V. & Hansen, T., 2023, I: Scientific Reports. 13, 10 s., 19638.

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14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

Gjesing, A. P., Engelbrechtsen, L., Cathrine B. Thuesen, A., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Steen Nielsen, J., Christensen, L. B., Thomsen, R. W., Johansson, K. E., Cagiada, M., Gersing, S., Hartmann-Petersen, R., Lindorff-Larsen, K., Vaag, A., Sørensen, H. T., Brandslund, I., Beck-Nielsen, H., Pedersen, O. & 2 flere, Rungby, J. & Hansen, T., 2022, I: Diabetes Research and Clinical Practice. 194, 9 s., 110159.

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3 Citationer (Scopus)

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Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

Borisevich, D., Schnurr, T. M., Engelbrechtsen, L., Rakitko, A., Ängquist, L., Ilinsky, V., Aadahl, M., Grarup, N., Pedersen, O., Sørensen, T. I. A. & Hansen, T., 2021, I: PLoS ONE. 16, 10, 16 s., e0258748.

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The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood

Schnurr, T. M., Morgen, C. S., Borisevich, D., Beaumont, R. N., Engelbrechtsen, L., Ängquist, L., Have, C. T., Freathy, R. M., Smith, G. D., Nohr, E. A., Hansen, T. & Sørensen, T. I. A., 2020, I: Scientific Reports. 10, 1, 10 s., 4806.

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pjx571 pjx571

Samarbejde og topforskningsområder i de sidste fem år

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Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood