Intet billede af Rasmus Hartmann-Petersen
  • Kilde: Scopus
1998 …2024

Publikationer pr. år

Personlig profil

CV

Personal Details

Name: Rasmus Hartmann-Petersen
Born: 1974
ORCID: 0000-0002-4155-7791
Phone: +45 26941565
E-mail: [email protected]

Education

2002   Ph.D., University of Copenhagen, Denmark
1998   M.Sc., University of Copenhagen, Denmark

Scientific Focus Areas

Intracellular protein degradation via the ubiquitin-proteasome system, with a particular focus on the protein quality control of disease-linked proteins and the role of intrinsically disordered proteins.

Positions

August 2022 -
Head of Section, Section for Biomolecular Sciences, University of Copenhagen, Denmark.

August 2017 -
Professor, Department of Biology, University of Copenhagen, Denmark.

January 2008 - August 2017
Associate Professor, Department of Biology, University of Copenhagen, Denmark.

July 2004 - January 2008
Assistant Professor, Department of Molecular Biology, University of Copenhagen, Denmark.

January 2002 - July 2004
Post Doc at the Human Genetics Unit, MRC, Edinburgh, Scotland.

Supervision and Teaching

Internal supervisor for >30 M.Sc. students, 11 Ph.D. students, 4 post docs.
Mentor for students following the biochemistry and molecular biomedicine program.
Voted as teacher of the year at the Department of Biology 2023.

Recent Outreach

Weekendavisen 2021, VM i molekylære puslespil.
Weekendavisen 2021, Molekylære stavefejl.
Weekendavisen 2017, Evolution i overhalingsbanen.

Bibliometrics

As of May 2023, 87 peer-reviewed publications, >4000 citations, H-index 37.

Undervisnings- og vejledningsområder

I teach on the following courses:

Gene technology (lectures, seminars, practicals), Protein Chemistry and Enzymology (lectures, practicals), Protein Science (lectures, seminars).

I supervise students on projects related to:

Protein Chemistry, Molecular Biology, Cell Biology & Genetics.

Sprogkundskaber

Danish & English

Interesseområder

Intracellular protein degradation, the 26S proteasome, the ubiquitin system, cellular redox control, protein folding, molecular chaperones, protein quality control, degrons, genetic diseases, variant classification.

Aktuel forskning

Our research activity is primarily centered on intracellular protein degradation via the ubiquitin-proteasome pathway. The ubiquitin-proteasome system is highly conserved and is the major pathway for intracellular proteolysis in all eukaryotic cells. Accordingly, ubiquitin-dependent protein degradation plays a pivotal role in the turnover of key regulatory proteins involved in a series of cellular processes, including cell cycle control, signal transduction, and protein folding. For a number of years a focus area for us has been how abnormal or misfolded proteins are targeted for degradation. To this end, we focus on genetic disorders and use yeast and mammalian cells in tissue culture as model systems, combined with a series of genetic, biochemical and molecular cell biological methods. In addition, we collaborate closely with a number of other research groups both in Denmark and abroad.

Emneord

  • Det Natur- og Biovidenskabelige Fakultet
  • Proteinkemi
  • Molekylærbiologi
  • Cellebiologi
  • Gærgenetik
  • Proteinnedbrydning
  • Ubiquitin
  • Proteasomer
  • Cellulær Protein Kvalitetskontrol
  • Molekylære Chaperoner
  • Cellulær Redox Regulering

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