GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K. & Teurlings, S. M. W. & 9 flere, Chi, C. C., Gee, C. L., Frølund, B., Kornum, B. R., van Woerden, G. M., Clausen, R. P., Kuriyan, J., Clarkson, A. N. & Wellendorph, P., 2021, I: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 s., e2108079118.

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Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity

Zhao, F., Atxabal, U., Mariottini, S., Yi, F., Lotti, J. S., Rouzbeh, N., Liu, N., Bunch, L., Hansen, K. B. & Clausen, R. P., 2022, I: Journal of Medicinal Chemistry. 65, 1, s. 734-746

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Stereoselective synthesis of novel 2′-(S)-CCG-IV analogues as potent NMDA receptor agonists

Maolanon, A., Papangelis, A., Kawiecki, D., Mou, T. C., Syrenne, J. T., Yi, F., Hansen, K. B. & Clausen, R. P., 2021, I: European Journal of Medicinal Chemistry. 212, 17 s., 113099.

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Improved synthetic route for the GluN2-specific NMDA receptor glycine site agonist AICP

Zhao, F., Rouzbeh, N., Hansen, K. B. & Clausen, R. P., 31 mar. 2020, I: Tetrahedron Letters. 61, 12, 4 s., 151653.

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Design of (R)-3-(5-Thienyl)carboxamido-2-aminopropanoic Acid Derivatives as Novel NMDA Receptor Glycine Site Agonists: Variation in Molecular Geometry to Improve Potency and Augment GluN2 Subunit-Specific Activity

Zhao, F., Atxabal, U., Mariottini, S., Yi, F., Lotti, J. S., Layeux, M. S., Currier, C. C., Maderia, M. P., Cornelison, L. E., Anderson, C. M., Schultz, E. P., Zhang, Z., Jiang, L., Gao, Z., Liu, N., Woodahl, E. L., Bunch, L., Hansen, K. B. & Clausen, R. P., 2025, I: Journal of Medicinal Chemistry. 68, 3, s. 3572–3590

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Evaluation of allosteric NMDA receptor modulation by GluN2A-selective antagonists using pharmacological equilibrium modeling

Lotti, J. S., Jones, J., Farnsworth, J. C., Yi, F., Zhao, F., Menniti, F. S., Volkmann, R. A., Clausen, R. P. & Hansen, K. B., 2025, I: Molecular Pharmacology. 106, 5, 17 s., 100004.

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In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs

Bechthold, E., Grey, L., Diamant, E., Schmidt, J., Steigerwald, R., Zhao, F., Hansen, K. B., Bunch, L., Clausen, R. P. & Wünsch, B., 2023, I: Biological Chemistry. 404, 4, s. 255-265

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Discovery of (R)-2-amino-3-triazolpropanoic acid derivatives as NMDA receptor glycine site agonists with GluN2 subunit-specific activity

Zhao, F., Mazis, G., Yi, F., Lotti, J. S., Layeux, M. S., Schultz, E. P., Bunch, L., Hansen, K. B. & Clausen, R. P., 2022, I: Frontiers in Chemistry. 10, 13 s., 1008233.

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