Publikationer pr. år
Publikationer pr. år
Personlig profil
CV
Yderligere oplysninger: Se højremenuen (Genveje): Hjemmeside
Kort præsentation
orcid.org/0000-0002-5773-6874
CV
orcid.org/0000-0002-5773-6874
Kort præsentation
orcid.org/0000-0002-5773-6874
Kort præsentation
Author or coauthor more than 185 articles or bookchapters in scientific journals or books, coeditor on 2 books and coinventor on 8 patents, h-index 50.
The main topic of research has been isolation of natural products with biological activities and optimizing of their structures to develop new drugs. The focus points have been development of mipsagargin from thapsigargin for treatment of cancer diseases and development of malaria drugs from licochalcone A.
Emneord
- Det Sundhedsvidenskabelige Fakultet
- Thapsigargin
- Mipsagargin
- Licochalcone A
- Bioactive natural products
- Structure elucidation
- Prodrug design
Publikation
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Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells
Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, S. B., Denmeade, S. R. & Isaacs, J. T., 2009, I: Molecular Cancer Therapeutics. 8, 5, s. 1340-1349Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
39 Citationer (Scopus) -
Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase
Paulsen, E. S., Villadsen, J., Tenori, E., Liu, H., Bonde, D. F., Lie, M. A., Bublitz, M., Olesen, C. L., Autzen, H. E., Dach, I., Sehgal, P., Nissen, P., Møller, J., Schiøtt, B. & Christensen, S. B., 9 maj 2013, I: Journal of Medicinal Chemistry. 56, 9, s. 3609-19 11 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
24 Citationer (Scopus) -
Development of β-lactams since 1986: Commentary on The discovery of penicillin and cephalosporins by Sydney Selwyn
Christensen, S. B., 2024, Hemodynamics and Immune Defense: Volume 3: Discoveries in Pharmacology, Second Edition. Elsevier, Bind 3. s. 279-282Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review
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Drugs That Changed Society: Microtubule-Targeting Agents Belonging to Taxanoids, Macrolides and Non-Ribosomal Peptides
Christensen, S. B., 2022, I: Molecules. 27, 17, 29 s., 5648.Publikation: Bidrag til tidsskrift › Review › peer review
Åben adgangFil18 Citationer (Scopus)95 Downloads (Pure) -
Validation of anti-malarial leads from natural products and traditional medicine for treatment of malaria
Christensen, S. B., 2022, In Evidence-Based validation of herbal medicine. Mukherjee, P. K. (red.). 2 udg. Amsterdam: Elsevier, s. 389-407Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review
2 Citationer (Scopus) -
Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams
Christensen, S. B., 2021, I: Molecules. 26, 19, 31 s., 6057.Publikation: Bidrag til tidsskrift › Review › peer review
Åben adgangFil81 Citationer (Scopus)91 Downloads (Pure) -
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
Christensen, S. B., Simonsen, H. T., Engedal, N., Nissen, P., Møller, J. V., Denmeade, S. R. & Isaacs, J. T., 2021, I: Progress in the chemistry of organic natural products. 115, s. 59-114Publikation: Bidrag til tidsskrift › Review › peer review
Fil9 Citationer (Scopus) -
Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics
Isaacs, J. T., Brennen, W. N., Christensen, S. B. & Denmeade, S. R., 2021, I: Molecules. 26, 24, 7469.Publikation: Bidrag til tidsskrift › Review › peer review
Åben adgangFil28 Citationer (Scopus)92 Downloads (Pure)
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DD-3: Natural Products as Leads in Drug Research: Dereplication, Lead Discovery and Innovation
Nielsen, J. (Paneldeltager) & Christensen, S. B. (Oplægsholder)
2 jul. 2019 → 4 jul. 2019Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag
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ULLA Summer School 2017
Nielsen, J. (Taler) & Christensen, S. B. (Taler)
11 jul. 2017Aktivitet: Deltagelse i arrangement eller begivenhed - typer › Deltagelse i workshop, seminar og kursus
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Natural Products that Changed the World
Christensen, S. B. (Foredragsholder)
5 nov. 2015Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag
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From Plant to Patient
Christensen, S. B. (Foredragsholder)
5 okt. 2015Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag
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From Plant to Patient
Christensen, S. B. (Foredragsholder)
21 sep. 2015 → 25 sep. 2015Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag
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From Plant to Patient
Christensen, S. B. (Foredragsholder)
30 jan. 2015Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag
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Essential Oils
Christensen, S. B. (Deltager)
30 jan. 2015Aktivitet: Deltagelse i arrangement eller begivenhed - typer › Deltagelse i workshop, seminar og kursus
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From Plant to Patient
Christensen, S. B. (Foredragsholder)
23 sep. 2014 → 26 sep. 2014Aktivitet: Tale eller præsentation - typer › Foredrag og mundtlige bidrag