Born: 1 November, 1954 in Copenhagen
Citizenship: Danish
Married – three sons
Address (private): Vingårds Alle 34, 2900 Hellerup, Denmark
Address (work): Section of Environmental Health, Dept. of Public Health, Øster Farimagsgade 5, DK 1014 K, Copenhagen, Denmark
Phone: (work) +4535327649; (mobile) +4526814889; (fax) +4535327610
E-mail: [email protected]
Education: Masters degree in Medicine, University of Copenhagen, January 1980
Academic degree: Dr. of Medical Science 1990
Appointments
1980-1986: Clinical appointments, mainly in internal medicine
1986-1998: Assistant professor, later associate professor in toxicology and environmental medicine at University of Copenhagen
From April 1998 onwards: Professor in Environmental Medicine at Department of Public Health, Faculty of Health Sciences, University of Copenhagen
2000-2015 Head of Section of Environmental Health, Dept. of Public Health, University of Copenhagen
2003-2010: Chairman of the Research Center for Environmental Health of the Danish Ministry for the Interior and Health, now Advisory Scientific Committee on Environmental Health, National Board of Health, Denmark
2007-2014 Member from 2013 Vicechairman of the board of The National Research Center for the Working Environment
2009-2015: Member of the Academic Council of the Health Science Faculty of University of Copenhagen
2015-2021: Head of Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen
Research interests
The aim of my research is to improve prevention of disease caused by environmental factors by better understanding the exposures and mechanisms involved. Particularly research in the fields of health effects ofparticles, molecular epidemiology, and oxidative DNA damage and repair.
The particle research comprises exposure and effects of outdoor and indoor air pollution as well as risks of engineered nanoparticles. The work spans the entire hierarchy of techniques from experimental models such as synthetic membranes, organotypic cell cultures and transgenic animals, the use of biomarkers and functional measures populationswith controlled exposure and interventions, to register-based epidemiology atthe aggregate level and influence of climate change. There is particular attention on mechanisms associated with oxidative stress-related genotoxic,vascular and aging effects in risk groups of genetically susceptible, foetuses, children and elderly people with and without diabetes and / or obesity and regulation of defense mechanisms such as DNA repair. The molecular epidemiology development includes measures of internal dose of environmental factors, dietary interactions, effects in the form of oxidative and chemical stress, thecellular response in the form of gene expression patterns, resulting DNA damageand related repair capacity, genetic susceptibility, cardiovascular functionand aging. Biomarkers of exposure and effects are applied in vulnerablepopulations and validated by the predictive value in relation to diseasedevelopment in large cohorts.
Major recent research achievements include demonstration of effects of nanoparticles on oxidative damage to DNA and vascular functions both in susceptible transgenic animal models and in humans, and that a number of biomarkers of exposure can predict risk of cancer in prospective settings.
Major grants and research leadership
Coordinator and grant holder of the Center of Excellence Air Pollution in a Life time Health Perspective (AIRPOLIFE) 2004-2010 granted 25 mill. Dkr. from the Danish Research Agency.
Coordinator and grant holder of the research program Health Effects of Air Pollution: Interactions between Oxidative stress and Diet (HEAPOD) 1999-2003 granted 14 mill. DKr. from the program Prevention and Health Promotion via the Research Councils.
Coordinator and grant holder of Center for Environment and Cancer, granted 6 mill. DKr. over 3 years from 2000 from The Environmental Research Center of the Danish Ministry for the Interior and Health
Coordinator of the health part (share 2.5 mill. Dkr. 2000-03) of the program Transport Research Impact on health and environment and Policy financed by the Strategic Environmental Research Program
Partner in ECNIS (Environment Cancer Nutrition and Individual Susceptibility) EU FP6 grant 2005-10; share 2005-2008: 4 mill. DKr.
Partner in ECNIS2 (Environment Cancer Nutrition and Individual Susceptibility) EU F7 grant 2011-13; share 0.6 mill. DKr.
Partner in ENPRA (Risk Assessment of Engineered Nanoparticles) EU FP7 grant 2009-12; share 1.5 mill. DKr.
Partner in NanoImpactNet, EU FP7 coordination and support action.
Partner in NANOKEM from the Working Environment Foundation 2007-10; share 1.3 mill. DKr.
Partner in BIOFUEL and WOODUSE from the Strategic Research Councils 2005-10; share 2 mill. DKr.
Grants from the Research Councils on health and disease 2004 and 2007 in total of 2.4 mill. DKr.
Grants from the Environmental Protection Agency and the Health Ministry 1.1 mill DKr. in 2007.
Partner in CISBO (Center for Indeklima og Sundhed i Boliger) from Realdania, share 2009-2014 5 mill. DKr.
Partner in Center for Pharmaceutical Nanotechnology and Nanotoxicology 2009-2014 share 3.6 mill. DKr.
Partner in Lundbeck Foundation Center for BioMembranes in NanoMedicine 2010-2015 share 3 mill. DKr.
Partner in Danish Nanosafety Center 2012-2015, share 1.8 mill. DKr
Grantholder of Mechanismsof action of adverse effects of nanoparticles at single cell level 2012-2016with 3 mill DKK from the Danish Council for Independent Research in Medical Sciences
10 competitive PhD grants from the Health Science Faculty at University of Copenhagen (2001-2012) corresponding to 15 mill DKr.
Research supervision
Supervisor of 44 (25 main supervisor) PhD students through completion, 24 pregraduate students and 16 guest researchers so far. At present main supervisor of 1 and cosupervisor of 2 active PhD students.
Mentor of 13 post.doc. fellows.
Selected mentorships
Mentor of Peter Møller (PhD 1999) from 1999 as post.doc./assistant professor. He achieved a Dr. Med. Sci. in 2005 and was appointed professor in Oxidative Stress in relation to Environment and Health at the Health Science Faculty in 2012
Mentor of Mette Sørensen from pregraduate level in 1998, during a subsequent PhD program and as post.doc. She is now senior researcher at the Danish Cancer Society and has received an ERC grant.
Selected pregraduate teaching
Teaching and course organization related to environmental health at multiple programs, including medicine, at the Faculty of Health Sciences, University of Copenhagen.
Recent cofounder of the new elite masters program in environmental chemistry and health.
Selected administrative experiences
Steffen Loft was chairman of the University of Copenhagen committee for administrative IT until 1998
Steffen Loft has from 2000 to 2015 been Head of Section of Environmental Health, Department of Public Health, Faculty of Health Sciences, University of Copenhagen, with currently around 35 researchers and technicians.
Steffen Loft has completed the University of Copenhagen Leadership Program 2010-2011
Steffen Loft has been on the board of Danish Toxicology Center (ATV Institute), The National Environmental Research Institute and The National Research Center for the Working Environment (Government Research Institutes)
Steffen Loft was from 2015-2021 head of Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen
Selected Public Outreach
Steffen Loft was Chairman 2003-2010, from 2010 member, of the Research Center for Environmental Health of the Danish Ministry for the Interior and Health, now Advisory Scientific Committee on Environmental Health, National Board of Health, Denmark. The committee also maintains an important portal for communication of Environment and Health science (http://miljoogsundhed.sst.dk/english/index.html)
Steffen Loft was Editor-in-Chief (2003-2010) now co-editor of the quarterly Danish science communication journal “Environment and Health” (Miljø og Sundhed) printed in >1000 copies addressed to stakeholders including all the relevant authorities.
Steffen Loft is very frequently used in media regarding environment and health, in particular regarding air pollution and nanoparticles.
International Conferences
Steffen Loft has organized a number of international conferences and workshops and has been invited as speaker and keynote speaker on multiple occasions.
Selected International Science Evaluation
Frequently PhD evaluator in Norway, Sweden and Finland
Grant evaluator in USA, UK, Netherlands, Italy, France, Germany, Norway, Sweden and Finland
Peer reviewer for the leading journals in the relevant fields
Editorial boards
Nanotoxicology (IF 5.2), Basic and Clinical Pharmacology and Toxicology (IF 4.1), Fibers (IF 4.0), Particle and Fibre Toxicology – leading journal in toxicology with IF 7.3
Publications
435 scientific papers in international peer-reviewed journals in the field, 22 international book chapters (no 17, 71, 92, 97, 109, 119, 122, 135, 151,158, 161, 179, 193, 226, 232, 237, 256, 296, 308, 352, 390, 454) and 9 publications in the Danish Medical Journal (no 5, 18, 21, 33, 57, 153, 154, 186, 271). The number of citations of the journal papers in ISI exceeds 21,000 totally or >5 citations per year per paper on average for the more than 250 papers published during the last 15 yr. Average impact factor of international journals published in during the last 3 years is >5. The H-index is currently 84 in ISI, 87 in Scopus and 104 in Google Scolar.
Complete list of publications for Steffen Loft
Complete list of publications for Steffen Loft
- Loft S, Jensen V, Rørsgaard S, Dyrberg V. Influence of moderate alcohol intake on thiopental anesthesia. Acta Anaesthesiol Scand 26: 22-26, 1982
- Vestergaard Olsen V, Loft S, Christensen KD. Serious reactions during malaria prophylaxis with pyrimethamine sulphadoxine. Lancet 1982 ii: 994
- Loft S, Jensen V, Rørsgaard S. Influence of moderate alcohol intake on wakening plasma thiopental concentration. Acta Anaesthesiol Scand 27: 266-269, 1983
- Loft S, Willumsen L. Tropical anamnesis disguising malignant lymphoma. Scand J Haematol 31: 168-172, 1983
- Christensen KD, Loft S, Vestergaard Olsen V. Alvorlige bivirkninger under anvendelse af sulfadoxin/pyrimetamin (Fansidar). Ugeskr Læger 145: 245-246, 1983
- Loft S, Boel J, Kyst A, Rasmussen B, Hansen SH, Døssing M. Increased microsomal enzyme activity after surgery under halothane and spinal anesthesia. Anesthesiology 62: 11-16, 1985
- Sonne J, Døssing M, Loft S, Andreasen PB. Antipyrine clearance in pneumonia. Clin Pharmacol Ther 37: 701-703, 1985
- Loft S, Haxholdt O, Døssing M. Antipyrine clearance in children from single saliva samples. Br J Clin Pharmacol 19: 698-700, 1985
- Døssing M, Loft S, Schroeder E. Jet fuel and liver function. Scand J Work Environment Health 11: 433-437, 1985
- Loft S, Sonne J, Pilsgaard H, Døssing M, Enghusen Poulsen H. Inhibition of antipyrine elimination by disulfiram and cimetidine: the effect of concomitant administration. Br J Clin Pharmacol 21: 75-77, 1986
- Haxholdt O, Loft S, Clemmensen A, Hjortsø E. Increased antipyrine clearance in children after surgery under halothane anaesthesia. Anaesthesia 41: 579-581, 1986
- Loft S, Døssing M, Poulsen HE, Sonne J, Olesen KL, Simonsen K, Andreasen PB. Influence of dose and route of administration on disposition of metronidazole and its major metabolites after intravenous and oral doses of 500 and 2000 mg. Eur J Clin Pharmacol 30: 467-473, 1986
- Laybourn C, Tønnesen P, Loft S, Sonne J, Døssing M. Pulmonary disease and antipyrine clearance. Clin Pharmacol Ther 40: 415-419, 1986
- Loft S, Poulsen HE, Sonne J, Døssing M, Pedersen KT, Jørgensen BG. Inhibition and induction of metronidazole and antipyrine metabolism. Eur J Clin Pharmacol 32: 35-41, 1987
- Loft S, Sonne J, Døssing M, Andreasen PB. Metronidazole pharmacokinetics in patients with hepatic encephalopathy. Scand J Gastroenterol 22: 117-123, 1987
- Sonne J, Døssing M, Poulsen HE, Pilsgaard H, Rasmussen B, Loft S. Effect of concomitant administration of cimetidine and phenobarbital on antipyrine elimination. Int J Clin Pharmacol Ther Toxicol 25: 194-196, 1987
- Poulsen HE, Loft S. Assessment of quantitative hepatic function: Antipyrine metabolism ‑ an update. Assessment and management of hepatobiliary disease, p. 191-196, 1987
- Døsing M, Sonne J, Loft S, Pedersen KT. Virkningen af miljøfaktorer, alder køn og menstruationscyklus på leverens lægemiddelomsætning. Ugeskr f læg 149: 2201-2204, 1987
- Loft S, Ewald T, Simonsen K, Christensen H, Sonne J, Døssing M. Influence of prednisolone on antipyrine elimination in patients with obstructive lung disease. Eur J Clin Pharmacol 33: 89-91, 1987
- Loft S, Olesen KL, Døssing M. Increased susceptibility to liver disease in relation to alcohol consumption in women. Scand J Gastroenterol 22: 1251-1256, 1987
- Sonne J, Døssing M, Loft S. Sygdom og hepatisk lægemiddelomsætning. Ugeskr f læg 150: 204-209, 1988
- Døssing M, Loft S, Sonne J, Schroeder E. Antipyrine and metronidazole metabolism during occupational exposure to gasoline. Int Arch Occup Envir Health 60: 115-118, 1988
- Loft S, Døssing M, Sonne J, Poulsen HE. Metronidazole clearance: A one-sample method and influencing factors. Clin Pharmacol Ther 43: 420-428, 1988
- Poulsen HE, Loft S. Antipyrine as model drug to study hepatic drug metabolism capacity in man. J Hepatol: 6: 374-382, 1988
- Sonne J, Loft S, Døssing M, Volmer-Larsen A, Olesen K-L, Victor MA. Bioavailability and pharmacokinetics of oxazepam. Eur J Clin Pharmacol 35: 385-389, 1988
- Sonne J, Poulsen HE, Loft S, Døssing M, Volmer-Larsen A, Simonsen K, Thyssen H. Therapeutic doses of codeine have no effect on acetaminophen clearance or metabolism. Eur J Clin Pharmacol 35: 109-111, 1988
- Loft S, Døssing M, Poulsen HE. Influence of age and consumption of tobacco alcohol and caffeine on antipyrine clearance. Human Toxicol 7: 277-280, 1988
- Loft S, Døssing M, Sonne J, Dalhoff K, Bjerrum K, Poulsen HE. Lack of effect of cimetidine on the metabolism of metronidazole in man. Eur J Clin Pharmacol 35: 65-68, 1988
- Larsen M, Loft S, Hommel E, Lund-Andersen H. Fluorescein and fluorescein monoglucuronide in plasma after intravenous injection of fluorescein. Acta Ophtalmologica Scand 66: 427-432, 1988
- Sonne J, Dragsted J, Loft S, Døssing M, Andreasen F. The influence of a very low-calorie diet on the clearance of oxazepam and antipyrine in humans. Eur J Clin Pharmacol 36: 407-409, 1989
- Loft S, Poulsen HE. Metronidazole and antipyrine metabolism in isolated rat hepatocytes: Influence of sex and enzyme induction and inhibition. Biochem Pharmacol 38, 1125-36, 1989
- Tvede KG, Loft S, Poulsen HE, Schou JS. Methyl parathion toxicity in rats is changed by pretreatment with the pesticides chlordecone, mirex and linuron. Archives of Toxicology Suppl 13: 446-447, 1989
- Ott P, Hansen PB, Dalhof K, Loft S, Poulsen HE, Analgetikaforbrug, -overdosering og -dødsfald i Danmark 1979-1986. Ugeskr f læg 152: 250-252, 1990
- Sonne J, Døssing M, Loft S, Olesen KL, Vollmer-Larsen A, Victor MA, Hamberg O, Thyssen H. Single dose pharmacokinetics and pharmacodynamics of oral oxazepam during concomitant administration of propanolol and labetalol. Br J Clin Pharmacol 29, 33-37, 1990
- Loft S, Poulsen. Metabolism of metronidazole and antipyrine in hepatocytes isolated from mouse and rat. Xenobiotica 20, 185-191, 1990
- Hinson JA, Roberts DW, Benson RW, Dalhoff K, Loft S, HE Poulsen. Mechanism of paracetamol toxicity. Lancet 335, 732, 1990
- Loft S. Metronidazole and antipyrine as probes for the study of foreign compound metabolism. Pharmacol Toxicol 66, suppl. VI, 1-31, 1990
- Hamberg O, Ovesen L, Dorfeldt A, Loft S, Sonne J. The effect of dietary energy and protein deficiency on drug metabolism. Eur J Clin Pharmacol 38, 567-570, 1990
- Ott P, Dalhoff K, Hansen PB, Loft S, Poulsen HE. Consumption, overdose and death from analgesics in a period with over-the-counter release of paracetamol in Denmark. J Int Med 227, 423-428, 1990
- Loft S, Egsmose C, Sonne J, Poulsen HE, Døssing M, Andreasen PB. Metronidazole elimination is preserved in the elderly, Hum Toxicol 9, 155-161, 1990
- Sonne J, Andreasen PB, Loft S, Døssing M, Andreasen F. Glucuronidation of oxazepam is not spared in patients with alcoholic cirrhosis and hepatic encephalopathy. Hepatology 11, 951-956, 1990
- Loft S, HE Poulsen. Prediction of xenobiotic metabolism by non-invasive methods. Pharmacol Toxicol 67, 101-108, 1990
- Sonne J, Boesgaard S, Poulsen HE, Loft S, Hansen JM, Døssing M, Andreasen F. Pharmacokinetics and pharmacodynamics of oxazepam and paracetamol in severe hypothyroidism. Br J Clin Pharmacol 30, 732-742, 1990
- Loft S, Nielsen AJ, Borg BE, Poulsen HE. Metronidazole and antipyrine metabolism in the rat: Clearance determination from one saliva sample. Xenobiotica 21, 33-46, 1991
- Vistisen K, Loft S, Poulsen HE. Cytochrome P450 IA2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise. Adv Exp Med Biol 283, 407-411
- Loft S, Otton SV, Lennard ML, Tucker GT, Poulsen HE: Characterization of metronidazole metabolism by human liver microsomes. Biochem Pharmacol 41, 1127-1134, 1991
- Sonne J, Loft S, Døssing M, Boesgaard S, Andreasen F. Single dose pharmacokinetics and pharmacodynamics in very elderly institutionalised subjects. Br J Clin Pharmacol 31, 719-722, 1991
- Sjovald S, Ahren B, Hansson P, Loft S, Poulsen HE, Bengmark S: Metabolic responses to intermittent hepatic deterialization in the rat. J Hepatol 13, 33-37, 1991
- Dalhoff K, Hansen PB, Ott P, Loft S, Poulsen HE. Acute ethanol administration reduces the antidote effect of N-acetylcysteine after acetaminophen overdose in mice. Hum Exp Toxicol 10, 431-433, 1991
- Sherson D, Sigsgaard T, Overgaard E, Loft S, Poulsen HE, Jongeneelen FJ: Interaction of smoking, uptake of polyaromatic hydrocarbons and cytochrome P450IA2 activity among foundry workers. Br J Ind Med 49, 197‑202, 1992
- Fischer-Nielsen A, Poulsen HE, Loft S. 8-hydroxydeoxyguanosine in vitro: effects of glutathione, ascorbate and 5-aminosalicylic acid. Free Rad Biol Med 13, 121-126, 1992
- Vistisen K, Poulsen HE, Loft S: Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. Carcinogenesis 13, 1561-1568, 1992
- Poulsen HE, Loft S, Andersen M, Andersen JR. Disulfiram therapy - adverse reactions and interactions. Acta Psyc Scand 86, suppl. 369, 1992
- Loft S, Vistisen K, Ewertz M, Tjønneland A, Overvad K, Poulsen HE: Oxidative DNA-damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index. Carcinogenesis 13, 2241-2247, 1992
- Loft S, Otte J, Poulsen HE, Sørensen H: Influence of indolyl glucosinolates (myrosinases) on the in vivo metabolism of metronidazole and antipyrine in the rat. Food Chem Toxicol 30, 927-935, 1992
- Poulsen HE, Loft S, Wasserman K. Cancer risk related to genetic polymorphisms in carcinogen metabolism and DNA repair. Pharmacol Toxicol 72: suppl I, 93-103, 1993
- Sherson D, Sigsgaard TI, Overgaard E, Loft S, Poulsen HE, Jongeneelen FC. Lungecancerrisici blandt støberiarbejdere. Ugeskr Læger 155: 620-623, 1993
- Jensen KG, Loft S, Doehmer J, Poulsen HE. Metabolism of phenacetin in V79 Chinese hamster cell cultures expressing rat liver CYP1A2 compared to isolated rat hepatocytes. Biochem Pharmacol 45: 1171-1173, 1993
- Brøsen K, Skjelbo E, Rasmussen BB, Poulsen HE, Loft S. Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem Pharmacol 45: 1211-1214, 1993
- Boesgaard S, Poulsen HE, Aldershvile J, Loft S, Anderson ME, Meister A: Acute effects of nitroglycerine depend on both plasma and intracellular sulhydryl compound levels in vivo. Effect of agents with different sulfhydryl modulating properties. Circulation 87: 547-553, 1993
- Jeding E, Loft S, Poulsen HE. No induction of extrahepatic antipyrine and metronidazole metabolism evaluated from partially hepatectomized rats. Xenobiotica 23: 411-418, 1993
- Loft S, Fischer-Nielsen A, Jeding IB, Vistisen K, Poulsen HE. 8-Hydroxydeoxyguanosine as a Urinary Biomarker of Oxidative DNA-damage. J Toxicol Environ Health 40: 397-410
- Ranek L, Dalhoff K, Poulsen HE, Brøsen K, Flachs H, Loft S, Wantzin P. Drug metabolism in subjects with previous halothane hepatitis. Scand J Gastroenterol 28: 677-680, 1993,
- Jensen KG, Önfelt A, Poulsen HE, Döhmer J, Loft S. Effects of Benzo[a]pyrene and ()-trans-7,8-dihydroxy-7,8,dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2. Carcinogenesis 14: 2115-2118, 1993
- Ding JW, Anderson R, Soltesz V, Willén R, Loft S, Poulsen HE, Pärsson H, Olsson K, Bengmark S. The effect of billiary decompression on bacterial translocation in jaundiced rats. Hepatobiliary Surgery 7: 99-110, 1993
- Fischer-Nielsen AF, Loft S, Jensen KG. Effect of ascorbate and 5-aminosalicylic acid on light induced 8-hydroxydeoxyguanosine formation in V79 Chinese hamster cells. Carcinogenesis 14: 2431-2433, 1993
- Poulsen HE, Loft S. The impact of genetic polymorphisms in risk assessment of drugs. Arch Toxicol suppl. 16: 211-222, 1994
- Boesgaard S, Aldershvile J, Poulsen HE, Loft S, Anderson ME, Meister A. Nitrate tolerance in vivo is not associated with depletion of arterial or venous thiol levels. Circ Res 74: 115-120, 1994
- Loft S, Astrup A, Bueman B, Poulsen HE. Oxidative DNA damage correlates with oxygen consumption in humans. FASEB J 8: 534-537, 1994
- Fischer-Nielsen A, Jeding IB, Loft S. Radiation induced formation of 8-hydroxy-2'-deoxyguanosine and its prevention by scavengers, Carcinogenesis 15: 1609-1612, 1994
- Poulsen HE, Lykkesfeldt J, Loft S. The oxidant and antioxidant functions of oestrogens. HRT's imact on menopausal changes. p. 91-102. Wells Medical Limited, 1994.
- Lykkesfeldt J, Loft S, Poulsen HE. Simultaneous determination of urinary free cortisol and 6ßhydroxycortisol by high-performance liquid chromatography as a measurement of human CYP3A activity. J Chromatogr 660: 23-29, 1994
- Loft S, Larsen PN, Rasmussen A, Fischer-Nielsen A, Bondesen S, Kirkegaard P, Rasmussen LS, Ejlersen E, Tornøe K, Bergholdt R, Poulsen HE. Oxidative DNA damage after transplantation of the liver and small intestine in pigs. Transplantation 59: 16-20, 1995
- Rasmussen BB, Mäenpää J, Pelkonen O, Loft S, Poulsen HE, Lykkesfeldt J, Brøsen K. Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine. Br J Clin Pharmacol 39: 151-159, 1995
- van Poppel G, Poulsen HE, Loft S, Verhagen H. No influence of beta-carotene on oxidative DNA damage in male smokers. J Natl Cancer Inst 87: 310-311, 1995
- Jensen KG, Poulsen HE, Doehmer J, Loft S. Kinetics and inhibition by fluvoxamine of phenacetin O-deethylation in V79 cells expressing human CYP1A2. Pharmacol Toxicol 76: 286-288, 1995
- Nielsen HB, Hanel B, Loft S, Poulsen HE, Pedersen BK, Diamant M, Vistisen K, Secher NH. Restricted pulmonary diffusion capacity after exercise is not an ARDS-like injury. J Sports Sciences 13: 109-113, 1995
- Verhagen H, Poulsen HE, Loft S, van Poppel G, Willems MI, van Bladeren PJ. Reduction of oxidative DNA damage in man by Brussels sprouts. Carcinogenesis 16: 969-970, 1995
- Fischer-Nielsen A, Corcoran GB, Poulsen HE, Kamandulis LM, Loft S. Menadione-induced DNA fragmentation without 8-oxo-7,8-dihydro-2'-deoxyguanosine formation in isolated rat hepatocytes. Biochem Pharmacol 49: 1469-1474, 1995
- Loft S, Velthuis-te Wierik EJM, van der Berg H, Poulsen HE. Energy restriction and oxidative DNA damage in humans. Cancer Epidemiology Biomarkers & Prevention 4: 515-519, 1995
- Poulsen HE, Loft S. Early biochemical markers of effect: enzyme induction, oncogene activation and markers of oxidative damage. Toxicology 101: 55-64, 1995
- Thomsen M, Loft S, Roberts D, Poulsen HE. CYP2E1 inhibition by propylene glycol prevents acetaminophen (paracetamol) hepatotoxicity in mice without CYP1A2 inhibition. Pharmacol Toxicol 76:286‑8 1995
- Lykkesfeldt J, Loft S, Poulsen HE. Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection - a reliable biomarker of oxidative stress ? Analytical Chemistry 229: 329-335, 1995
- Velthuis-te Wierik EJM, van Leeuwen R, Hendriks HFJ, Verhagen H, Loft S, Poulsen HE, van der Berg H. Moderate energy restriction does not affect parameters of oxidative stress and genotoxicity in humans. J Nutr 125: 2631‑2639, 1995.
- Jensen KG, Poulsen HE, Doehmer J, Loft S. Paracetamol induced spindel disturbances in V79 cells with and without expression of human CYP1A2. Pharmacol Toxicol, 78: 224-228, 1996
- Tuo J, Loft S, Thomsen M, Poulsen HE. Ex vivo time-dependent cell-DNA-degradation shown by single cell gel electrophoresis. Pharmacol Toxicol 78: 55-57, 1996
- Loft S, Poulsen HE. Cancer risk and oxidative DNA damage in man. J Mol Med 74: 297-312, 1996
- Lykkesfeldt J, Prieme H, Loft S, Poulsen HE. Effect of smoking cessation on plasma ascorbic acid . Br Med J 313: 91, 1996
- Poulsen HE, Loft S, Vistisen K. Extreme exercise and oxidative DNA modification. J Sports Med 14: 343-346, 1996
- Jeppesen U, Gram LF, Vistisen K, Loft S, Poulsen HE, Brosen K. Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine. Eur J Clin Pharmacol 51: 73-78, 1996
- Tuo J, Loft S, Thomsen M, Poulsen HE. Benzene induced genotoxicity in mice in vivo detected by the comet assay: reduction by CYP2E1 inhibition. Mutation Res 368: 213-219, 1996
- Prieme H, Loft S, Cutler RG, Poulsen HE. Measurement of oxidative DNA injury in humans: evaluation of a comercially available ELISA assay. 78-82 i Natural Antioxidants & Food Quality in Atherosclerosis and Cancer Prevention. The Royal Society of Chemistry 1996.
- Jeppesen U, Loft S, Poulsen HE, Brosen K. A fluvoxamine-caffeine interaction study. Pharmacogenetics 6: 213-222, 1996
- Loft S, Jensen KG, Ringby L-L, Poulsen HE, Doehmer J. Kinetic Studies in Engineered V79 Cells in Comparison with Primary Hepatocytes and Human Liver Microsomes. Exp Toxicol Pathol 48 suppl. II: 249-255, 1996
- Prieme H, Loft S, Nyyssönen K, Salonen JT, Poulsen HE. No effect of supplementation with vitamin E, ascorbic acid or coenzyme Q10 in humans on oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2'-deoxyguanosine. Am J Clin Nutr 65: 503-507, 1997
- Vistisen K, Priemé H, Okkels H, Vallentin S, Loft S, Olsen JH, Poulsen HE. Genotype and phenotype of glutathione S-transferase µ in testicular cancer. Pharmacogenetics 7: 21-25, 1997
- Poulsen HE, Loft S, Prieme H, Salonen J. Antioxidants. In Haunsø S, Aldershvile J, Svendsen JH eds. Coronary Microcirculation during Ischaemia and Reperfusion. Alfred Benzon Symposium 41: 455-461, 1997
- Lykkesfeldt J, Loft S, Nielsen JB, Andersen HR, Poulsen HE. Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking. Am J Clin Nutrition 65: 503-507, 1997.
- Deng X-S, Tuo J, Poulsen HE, Loft S. 2-Nitropropane induced DNA Damage in Rat Bone Marrow. Mutation Res 391: 165-169, 1997
- Klarlund M, Prieme H, Loft S, Poulsen HE. Smoking cessation dose not change urinary albumin excretion in normal subjects. Scand J Clin Lab Invest 57: 513-520, 1997
- Cadenas S, Barja G, Poulsen HE, Loft S. Oxidative DNA Damage Estimated by oxo8dG in the Liver of Guinea Pigs Supplemented with Graded Dietary Doses of Ascorbic Acid and α-Tocopherol. Carcinogenesis 18: 2373-2377, 1997
- Prieme H, Loft S, Klarlund M, Grønbæk K,Tønnesen P, Poulsen HE. Effect of smoking cessation on oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion. Carcinogenenesis¨19: 347-351, 1998.
- Poulsen HE, Prieme H, Loft S. Role of oxidative DNA damage in cancer initiation and promotion. Eur J Cancer Prevent 7: 9-16, 1998.
- Prieme H, Nyyssönen K, Grønbæk K, Klarlund M, Loft S, Tønnesen P, Salonen JT, Poulsen HE. Randomized controlled smoking cessation study: transient increase in plasma high density lipoprotein but no change in lipoprotein oxidation resistance. Scand J Clin Lab Invest 58:11-18, 1998
- Loft S, Poulsen HE. Estimation of oxidative DNA damage in man from urinary excretion of repair products. Acta Biochimica Polonica 45: 133-144, 1998
- Deng X-S, Tuo J, Poulsen HE, Loft S. Prevention of oxidative DNA damage by Brussels sprouts in rats. Free Rad Res 28: 323-333, 1998.
- Tuo J, Wolff SP, Loft S, Poulsen HE. Formation of nitrated and hydroxylated aromatic compounds from benzene and peroxynitrite, a possible mechanism of berzene genotoxicity. Free Radical Res 28: 369-375, 1998
- Poulsen HE, Weimann A, Salonen J, Loft S, Cadet J, Douki T, Ravanat J-L Does vitamin C have a pro-oxidant effect. Nature 395: 231-232, 1998
- Loft S, Poulsen HE. Measurement of oxidative damage to DNA: interpretation of nuclear levels and urinary excretion of repair products in DNA damage and Repair: Oxygen Radical Effects, Cellular Protection and Biological Consequences. M. Dizdaroglu, Karyaka, Ed. NATO ASI Series pp. 267-281. Plenum Press, New York 1998
- Loft S, Deng X-S, Tuo J, Wellejus A, Sørensen M, Poulsen. Experimental study of oxidative DNA damage. Free Rad Res 29: 525-539, 1998
- Poulsen H, Loft S, Prieme H, Vistisen K, Lykkesfeldt J, Nyyssonen K, Salonen JT Oxidative DNA damage in vivo, interpretation, relation to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine correction. Free Rad Res 29: 565-571, 1998
- Loft S, E. B. Thorling, H. E. Poulsen. High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion in rats. Free Rad Res 29: 595-600, 1998
- Haderslev KV. Sonne J. Poulsen HE. Loft S. Paracetamol metabolism in patients with ulcerative colitis. Br J Clin Pharmacol 46: 513-6, 1998
- Tuo J, Deng X-S, Loft S, Poulsen HE. Dexamethasone ameliorates oxidative DNA damage induced by benzene and LPS in mouse bone marrow. Free Rad Res 30: 29-36, 1999
- Loft S, Poulsen HE. Markers of oxidative damage to DNA - antioxidants and molecular damage. Meth Enzymol 300: 166-184, 1999
- Autrup H, Daneshvar B, Dragsted LO, Gamborg M, Hansen ÅM, Loft S, Okkels H, Nielsen F, Nielsen PS, Raffn E, Wallin H, Knudsen LE. Biomarkers for exposure to ambient air pollution – comparison of carcinogen adduct levels with other exposure markers and markers for oxidative stress. Environ Health Perspec 107: 233-238, 1999
- Loft S, Poulsen HE, Vistisen K, Knudsen LE. Increased excretion of 8-oxo-7,8-dihydro-deoxyguanosine, a biomarker of oxidative DNA damage, in urban bus drivers. Mutation Res 441: 11-19, 1999
- Tuo J, Loft S, Poulsen HE. Enhanced benzene-induced DNA damage in PMA stimulated cells in vitro and LPS treated animals. Free Rad Biol Med 26: 801-808, 1999
- Poulsen HE, Prieme H, Loft S. Interpretation of oxidative DNA modification: relation between tissue levels, excretion of urinary repair products and single cell gel electrophoresis (comet assay). in DNA and Free Radicals: Techniques, Mechanisms & Applications. Eds Aruoma OI & Halliwell B. pp. 262-270,1999.
- Poulsen HE, Weimann A, Loft S. Methods to detect DNA damage by free radicals, relation to exercise. Proc Nutr Soc 58. 1-7, 1999
- Wellejus A, Poulsen HE, Loft S. Iron overload induces oxidative DNA damage in rat sperm cells. Free Rad Res 32: 75-83, 2000
- Poulsen HE, Loft S, Weimann A. Urinary measurement of 8-oxodG (8-oxo-2’-deoxyguanosine). in Measuring in vivo oxidative damage: a practical approach. Eds Griffiths H & Lunec J. Jon Wiley & Sons Ltd, Chichester UK 2000, pp. 69-80.
- Sørensen M, Loft S. No significant paraquat-induced oxidative DNA damage in rats. Free Rad Res, 32: 423-428, 2000
- Zhu C, Poulsen HE, Loft S. Inhibition of Oxidative DNA Damage In Vitro by extracts of Brussels Sprouts. Free Radical Res 33: 187-196, 2000
- Collins AR, Brown J, Bogdanov M, Cadet J, Cooke M, Douki T, Dunster C, Eakins J, Epe B, Evans M, Farmer P, Gedik CM, Halliwell B, Herbert K, Hofer T, Hutchinson R, Jenner A, Jones GDD, Kasai H, Kelly F, Lloret A, Loft S, Lunec J, McEwan M, Moller L, Olinski R, Podmore I, Poulsen H, Ravanat JL, Rees JF, Reetz F, Shertzer H, Spiegelhalder B, Turesky R, Tyrrell R, Vina J, Vinicombe D, Weimann A, de Wergifosse B, Wood SG. Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage. Free Radical Res 32: 333-341, 2000
- Salonen JT, Porkkala-Sarataho E Nyyssönen K, Kaikkonen J, Salonen R, Ristonmaa U, Diczfalusy U, Brigelius-Flohe R, Loft S, Poulsen HE. Long-term effects of vitamin E, vitamin C and combination supplementation on urinary 8-oxodeoxyguanosine, cholesterol oxidation products and oxidation resistance of lipids in non-depleted men. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2087-2093, 2000
- Tuo J, Liu L, Poulsen HE, Weimann A, Svendsen, Loft S. Importance of guanine nitration and hydroxylation in DNA in vitro and in vivo. Free Radical Biol Med 29: 147-155, 2000
- Møller P, Knudsen LE, Loft S, Wallin H. The comet assay as a rapid test in biomonitoring occupational exposure to DNA damaging agents and effect of confounding factors. Cancer Epidemiol Biomarkers Prev 9:1005-1015, 2000
- Loft S, Poulsen HE. Antioxidant intervention studies related to DNA Damage, DNA repair and gene expression. Free Radical Res 33: S67-83, 2000
- Poulsen HE, Jensen BR, Weimann A, Jensen SA, Sørensen M, Loft S. Antioxidants, DNA damage and gene expression. Free Radical Res 33: S33-40, 2000
- Kruse P, Anderson M, Loft S. Minimum signs of oxidative stress during acute pancreatitis in rats. Free Radical Biol Med 30:309-317, 2001
- Hertel O, Solvang Jensen S, Andersen HV, Palmgren F, Wåhlin P, Skov H, Nielsen IV, Sørensen M, Loft S, Raaschou-Nielsen O. Human exposure to traffic pollution. Experience from Danish studies. Pure Appl Chem 73 137-145, 2001
- M Sørensen, BR Jensen, HE Poulsen, X-S Deng, N Tygstrup, K Dalhoff, S Loft. Increase in oxidative DNA damage after administration of a Brussels sprouts extract. Food Chem Toxicol 39: 533-540, 2001
- P Møller, C Lundby, S Loft, NV Olsen. Acute hypoxia and hypoxic exercise induces DNA strand breaks and oxidative DNA damage in humans. FASEB J 15: 1181-86, 2001
- LO Dragsted, JF Young, S Loft, B Sandström. Biomarkers of oxidative stress and of antioxidative defence: relationship to intervention with antioxidant-rich foods. in Micornutrients and Health: Molecular Biological Mechanisms. Eds. K Nesaretnam, L Packer. AOCS Press, Champaign, IL, USA, 2001. pp. 272-278.
- Z Chunying, S Loft. Brussels Sprouts Extracts and Induction of Oxidative DNA Damage in Human Lymphocytes. Food Chem Res 39: 533-40, 2001
- LE Knudsen, S Loft, H Autrup. Risk assessment, the importance of genetic polymorphisms in man. Mutation Res, 482: 83-8, 2001
- A Wellejus, S Loft. Receptor-Mediated 17a-Ethynylestradiol-Induced Oxidative DNA Damage in Rat Testicular Cells. FASEB J 16: 195-201, 2002
- S Vestergaard, S Loft, P Møller. Role of inducible nitrogen oxide synthase in benzene-induced oxidative DNA damage in the bone marrow of mice. Free Rad Biol Med 32:481-484, 2002
- Young JF, Dragsted LO, Haraldsdóttir J, Daneshvar B, Kall MA, Loft S, Nilsson L, Rasmussen SE, Mayer B, Lauridsen ST, Huynh-Ba T, Hermetter A, Sandström B. Green tea extract only affects markers of oxidative status postprandially. Br J Nutr 87: 343-355, 2002
- Collins AR, Gedik CM, Wood S, White A, Bubois J, Duez P, Rees JF, Legall R, Degand L, Loft S, Jensen A, Poulsen H, Weimann A, Jensen BR, Cadet, J, Douki T, Ravanat JL, Faure H, Tripier M, Morel I, Sergent O, Cillard P, Morin B, Epe B, Phoa N, Hartwig A, Pelzer A, Dolara P, Casalini C, Guglielmi F, Luceri C, Kasai H, Kido R, Olinski R, Bialkowski K, Duracková Z, Hlincikova L, Korytar P, Dusinska M, Mislanova C, Vina J, Lloret A, Möller L, Hofer T, Gremaud E, Fay L, Stadler R, Eakins J, Pogna F, O’Brien J, Elliott R, Astley S, Bailley A, Herbet K, Chauhan D, Kelly F, Dunster C, Lunec J, Podmore I, Patel P, Johnson S, Evans M, White A, Tyrrell R. Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydrooxoguanine/8-oxo-7,8-dihydro-2’-deoxyguanosine. Free Radical Res 36: 239-245, 2002
- G Jürgens, HR Christensen, K Brøsen, J Sonne, S Loft, NV Olsen. Acute hypoxia and cytochorme P450-mediated hepatic drug metabolism in humans. Clin Pharmacol Ther 71: 214-221, 2002
- A Wellejus, M Dalgaard, S Loft. Oxidative DNA damage in male Wistar rats exposed to dibutylphthalate.. J Toxicol Environ Health A 65: 813-24 2002
- Griffiths HR, Møller L, Bartosz G, Bast A, Bertoni-Freddari C, Collins A, Coolen S, Haenen G, Loft S, Lunec J, Olinski O, Parry J, Pompella A, Poulsen HE, Verhagen H. Biomarkers. Mol Asp Med 23: 101-208, 2002
- P Møller, S Loft. Oxidative DNA damage in white blood cells of humans in dietary antioxidant supplementation studies. Am J Clin Nutr 76: 303-310, 2002
- Dragsted, L.O., Daneshvar, B., Vogel U., Autrup, H.N., Wallin H., Risom, L., Møller., P., Mølck, A.M., Hansen, M., Poulsen, H.E., Loft, S. A sucrose-rich diet increases mutation in the rat colon, Cancer Res 62: 4339-4346, 2002
- P Møller, H Wallin, U Vogel, H Autrup, L Risom, B Daneshvar, LO Dragsted, HE Poulsen, S Loft Genotoxicity and mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of Big Blue™ rats: role of DNA adducts, strand breakage, DNA repair and oxidative damage, Carcinogenesis 23: 1379-1385, 2002
- Besaratinia A, Maas LM, Brouwer EMC, Moonen EJC, De Kok TMCM, Loft S, Kleinjans JCS, Van Schooten FJ. A molecular dosimetry approach to assess human exposure to environmental tobacco smoke in pubs. Carcinogenesis 23: 1171-1176, 2002
- B Riis, L Risom, S Loft, and HE Poulsen Increased OGG1 expression without increased incision activity and changes in 8-oxodeoxyguanosine levels after partial hepatectomy. DNA Repair 1: 419-424, 2002
- B Riis, L Risom, S Loft, and HE Poulsen. Foetal levels of OGG1 expression and incision activity in rats are higher than in adult rats while 8-oxo-2’-deoxyguanosine levels are unchanged. DNA Repair 1: 709-717, 2002
- Loft S, Møller P, Sørensen M, Poulsen HE. Oxidative damage to DNA – human studies. Chemicals in the 21st Proceedings of the Fourth Princess Chulabhorn International Science Congress, p 199-207, 2002.
- U Vogel, P Møller, L Dragsted, S Loft, A Pedersen, B Sandström Inter-individual variation, seasonal variation and close correlation of OGG1 and ERCC1 mRNA levels in full blood from healthy volunteers. Carcinogenesis 23:1505-1509, 2002
- M-L Vrang, O Hertel, F Palmgren, P Wåhlin, O Raaschou-Nielsen, S Loft. Helbredseffekter af trafikgenererede ultrafine partikler. Ugeskrift f Læg 34: 3937-41, 2002
- Raaschou-Nielsen, F Palmgren, S Solvang Jensen, P Wåhlin, R Berkowicz, O Hertel, M-L Vrang, S Loft. Helbredseffekter af partikulær luftforurening i Danmark – et forsøg på kvantificering.. Ugeskrift f Læg 34: 3959-3963, 2002
- J Bornholdt, M Dybdahl, U Vogel, LO Dragsted, S Loft, H Wallin. Inhalation of ozone induces DNA strand breaks and inflammation in mice, Mutation Res 520: 63-68, 2002
- A Collins, C Gedik, N Vaughan, S Wood, A White , J Dubois, P Duez, D Gilles, B Martine, J-F Rees, S Loft, P. Møller, H Poulsen, B Riis Jensen, A Weimann, J Cadet, T Douki, J-L Ravanat, S Sauvaigo, H Faure, Isabelle Morel, B Morin, B Epe, N Phoa, A Hartwig, P Dolara, C Casalini, L Giovannelli, M Lodovici, R Olinski, K Bialkowski, M Foksinski, D Gackowski, Z Durakov, L Hlinikov, P Korytar, M Sivonov, M Dušinská, C Mislanov, J Viña, A Lloret, L Möller, T Hofer, J Nygren, E Gremaud, K Herbert, J Lunec, M Cooke, M, P Patel, I Podmore, A White , C Wild, L Hardie, J Olliver, E. Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus. Carcinogenesis 23: 2129-2133, 2002
- Sørensen M, Dragsted LO, Hertel O, Knudsen LE, Loft S. Personal PM5 exposure and markers of oxidative stress in blood, Environ Health Perspectives 111:161-6, 2003
- Loft S, Vogel U, Risom L, Møller P, Riis B, Poulsen HE, Wallin H. Oxidative DNA damage and expression of DNA repair enzymes. XI Biennial Meeting of the Society for Free Radical Research International. Monduzzi Editore, Bologna, 2003, p. 747-755.
- Zhu C and Loft Effect of chemopreventive compounds from Brassica vegetables on NAD(P)H: Quinone Reductase and induction of DNA strand breaks in murine hepa 1c1c7 cells. Food Chem Toxicol 41: 455-462, 2003
- Sørensen M, Autrup H, Hertel O, Wallin H, Knudsen LE, Loft S. Personal exposure to PM5 in an urban environment and biomarkers of genotoxicity. Cancer Epidemiol Biomarkers Prev 12: 191-196, 2003
- HE Poulsen, S Loft, BR Jensen, M Sørensen A Weimann. HPLC-ECD, HPLC-MS/MS (Urinary Biomarkers). in Oxidative Stress and Aging – Advances in Basic Science, Diagnostics and Intervention Eds. RG Cutler and H Rodriques. World Scientific Publishing Company, Singapore 2003. pp 233-256.
- Collins A, Gedik C, Vaughan N, Wood S, White A; Dubois J, Duez P, Dehon G, Rees JF, Loft S, Møller P, Poulsen H, Riis B, Weimann A, Cadet J, Douki T, Ravanat JL, Sauvaigo S, Faure H, Morel I, Morin B, Epe B, Phoa N, Hartwig A, Schwerdtle T, Dolara P, Giovannelli L, Lodovici M, Olinski R, Bialkowski K, Foksinski M, Gackowski D, Duračková Z, Hlinčiková L, Korytar P, Sivonová M, Dušinská M, Mislanová C , Viña J, Lloret A, Möller L, Hofer T, Nygren J, Gremaud E, Herbert K, Chauhan D, Lunec J, Cooke M, Evans M, Patel P, Podmore I, White A, Wild C, Hardie L, Olliver J, Smith E. Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. Free Radicals Biol Med 34: 1089-1099, 2003
- M Sørensen, H Skov, H Autrup, O Hertel, S Loft. Urban Benzene Exposure and Oxidative DNA Damage. Sci Total Environ 309: 69-80, 2003
- P Møller, B Daneshvar, S Loft, H Wallin, HE. Poulsen, H Autrup, LO Dragsted. Oxidative DNA damage in vitamin C supplemented guinea pigs after intratracheal instillation of diesel exhaust particles. Toxicol Appl Pharmacol 189: 39-44, 2003
- Loft S, Kold-Jensen T, Hjøllund NH, Giwercman A, Gyllemborg J, Ernst E, Olsen J, Scheike T, Poulsen HE, Bonde JP. Oxidative DNA damage in human sperm influences time to pregnancy. Human Reproduction 18: 1265-1272, 2003
- P Møller, Hansen M, Autrup A, Bornholt J, U Vogel, H Autrup, Mølck AM, H Wallin, LO Dragsted, HE Poulsen, S Loft. Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of BigBlueTM Muation Res 527: 91-7, 2003
- Olsen A, Tjønneland A, Thomsen B, Loft S, Stripp C, Overvad K, Møller S, Ewertz, Olsen JH. Fruits, vegetables and risk of breast cancer among postmenopausal women according to estrogen receptor status. J Nutr 133: 2342–2347, 2003
- Loft S, , Møller P Vogel U, Risom L, Riis B, Poulsen HE, Dybdal M, Dragsted LO, Knudsen LE, Wallin H. Oxidative stress by environmental agents. J Univ Occup Environ Health 25 suppl. 1: 47-59, 2003
- Risom L, Møller P, Hansen M, Autrup H, Bornholt J, Vogel U, Wallin H, Poulsen HE, Dragsted LO, Loft S. Dietary low-dose sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big BlueÒ Arch Toxicol 77: 651-656, 2003
- Vogel U, Danesvar B, Autrup H, Risom L, Weimann A, Poulsen HE, Møller P, Loft S, Wallin H, Dragsted L. Lard-increased mRNA levels of the DNA repair gene ERCC1 and decreased bulky DNA adducts in rat liver. Free Radical Res 37: 947-956, 2003
- Risom L, Møller P, Vogel U, Kristjansen PEG, Loft S. X-ray-induced oxidative stress: DNA damage and gene expression of HO-1, ERCC1 and OGG1 in mouse lung. Free Radical Res 37: 957-966, 2003
- Lundby C, Pilegaard H, van Hall G, Sander M, Calbet J, Loft S, Møller P. Oxidative DNA damage and repair in skeletal muscle of humans exposed to high altitude hypoxia. Toxicology 192: 229-36, 2003
- Risom L, Dybdahl M, Bornholdt J, Vogel U, Wallin H, Møller P, Loft S. Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation. Carcinogenesis 24: 1847-52, 2003
- Dybdahl, M Risom L, Møller P, Autrup H, Wallin H,Vogel U, Bornholdt J, Daneshvar B, Dragsted, L Weimann A, Poulsen HE, Loft S. DNA adduct formation and oxidative stress in colon and liver of Big Blue® rats after dietary exposure to diesel particles. Carcinogenesis 24:1759-1766, 2003
- Møller P, Vogel U, Pedersen A, Dragsted LO, Sandström B, Loft S. No effect of 600 g fruit and vegetables per day on oxidative DNA damage and repair in healthy non-smokers. Cancer Epidemiol Biomarkers Prev 12:1016-22, 2003
- Sørensen M, Autrup H, Møller P, Hertel O, Jensen SS, Vinzents P, Knudsen LE, Loft S. Linking exposure to environmental pollutants with biological effects. Mutation Res - Rev Mutation Res 544: 555-571, 2003
- Kramer I, Dalhoff K, Clemmesen JO, Loft S, Poulsen HE. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans. Eur J Clin Pharmacol 59:775-778. 2003
- Hansen ÅM, Wallin H, Binderup ML, Dybdahl M, Autrup H, Loft S, Knudsen LE. Urinary 1-hydroxypyrene and mutagenicity in bus drivers and mail carriers exposed to urban air pollution in Denmark. Mutation Res - Gen Toxicol Environ Mutagenesis. 557; 7-17, 2004
- Poulsen HE, Møller P, Lykkesfeldt J, Weimann A, Loft S. Vitamin C and Oxidative Damage to DNA. In Vitamin C, Functions and Biochemistry in Animals and Plants. Eds.: Asard H, May JM, Smirnoff N. BIOS Scientific Publishers, UK 2004, pp 189-202.
- Wellejus A, Bornholdt J, Vogel UB, Risom L, Wiger R, Loft S. Cell-specific oxidative DNA damage induced by estrogen in rat testicular cells in vitro. Toxicol Lett 150: 317-323, 2004
- Müller AK, Olatunde Farombi E, Møller P, Autrup H, Vogel U, Wallin H, Dragsted LO, Loft S, Binderup ML. DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue® rats. Mutation Res - Gen Toxicol Environ Mutagenesis 550:123-32, 2004
- Møller P, Loft S, Alfthan G, Freese R. Oxidative DNA damage in circulating mononuclear blood cells after ingestion of blackcurrant juice or anthocyanin-rich drink. Mutation Res - Fund Mol Mech 551:119-26, 2004
- Møller P, Loft S. Interventions with antioxidants and nutrients in relation to oxidative DNA damage and repair. Mutation Res - Fund Mol Mech 55:79-89, 2004
- Dragsted LO, Pedersen A, Hermetter A, Basu S, Hansen M, Ravn-Haren G, Kall M, Breinholt V, Jacobsen J, Castenmiller J, Stagsted J, Skibsted L, Nielsen SE, Loft S, Sandström B. The 6-a-day study: Effects of fruits and vegetables on markers of oxidative stress and defence in healthy non-smokers. Am J Clin Nutr 79:1060-72, 2004
- Vistisen K, Loft S, Olsen JH, Vallentin S, Ottesen S, Hirsch FR, Poulsen HE. Low CYP1A2 activity associated with testicular cancer. Carcinogenesis 25: 923-9, 2004
- Møller P, Loft S. Oksidative DNA skader i humane leukocytter i antioksidant interventionsstudier. Ugeskr f Læg. 166:1902-4, 2004
- Hansen M, Hald MT, Autrup H, Vogel U, Bornholdt J, Møller P, Mølck A-M, Lindecrona R, Poulsen HE, Wallin H, Loft S, Dragsted LO. Sucrose and IQ induced mutations in rat colon: no effect of sucrose on the mutation spectrum. Mutation Res - Fund Mol Mech 554: 279-286, 2004
- Dybdahl M, Risom L, Bornholdt J, Autrup H, Loft S, Wallin H. Inflammatory and genotoxic effects of diesel particles in vitro and in vivo. Mutation Res - Gen Toxicol Environ Mutagenesis 562: 119-131, 2004
- Sørensen M, Poole J, Autrup H, Muzyka V, Jensen A, Loft S, Knudsen LE. Benzene exposure assessed by metabolite excretion in Estonian oil shale mine workers: influence of GST polymorphisms. Cancer Epidemiol Biomarker Prev 13: 1729-1735, 2004
- Møller P, Viscovich M, Lykkesfeldt J, Loft S, Jensen A, Poulsen HE. Vitamin C supplementation decreases oxidative DNA damage in mononuclear blood cells of smokers. Eur J Nutr 43: 267-274, 2004
- Olsen A, Knudsen KEB, Thomsen BL, Loft S, Stripp C, Overvad K, Møller S, Tjønneland A. Plasma enterolactone and breast cancer incidence rate according to estrogen receptor status. Cancer Epidemiol Biomarker Prev13: 2084-2089, 2004
- Møller P, Friis G, Christensen PH, Risom L, Plesner G, Kjærsgaard J, Vinzents P, Loft S, Jensen A, Tved M. Intra-laboratory comet assay sample scoring exercise for determination of formamidopyrimidine DNA glycosylase sites in human mononuclear blood cell DNA. Free Radical Res 11: 1207–1214, 2004.
- Agudo A, Bailey BS, Bradlow HL, Byers T, Chung L, Dragsted LO, Hayes J, Hecht SS, Johnson IT, Kassie F, Loft, S, Manson MM, Miller AB, Mithen R, Nishikawa A, Schut HAJ, Seow A, Stoner G, Taioli E, Thornalley JP, Vang O, Zhang Y, IARC Working Group on the Evaluation of Cancer-Preventive Agents. Cruciferous vegetables, isothiocyanates and indoles. IARC Handbooks of Cancer Prevention 9, Lyon, IARC, pp. 1-262, 2004
- Saber AT, Bornholdt J, Dybdahl M, Sharma AK, Loft S, Vogel U, Wallin H. Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation. Arch Toxicol 79:177-82, 2005
- Avobge PH, Ayi-Fanou L, Autrup H, Loft S, Fayomi B, Sanni A, Vinzents P, Peter Møller. Ultrafine particulate matter and high-level benzene urban air pollution in relation to oxidative DNA damage. Carcinogenesis 26: 613-20, 2005
- Bak H, Christensen J, Thomsen BL, Tjønneland A, Overvad K, Loft S, Raaschou-Nielsen O. Physical activity and risk for lung cancer in a Danish cohort. Int J Cancer, 116: 439-44, 2005
- LO Dragsted, G Ravn-Haren, M Hansen, M Kall, V Breinholt, J Jakobsen, SE Rasmussen, A Pedersen, B Sandström, A Hermetter, S Basu, J Castenmiller, J Stagsted, LH Skibsted, S Loft. Effect of changes in fruit and vegetable intake on plasma antioxidant defences in humans - reply. Am J Clin Nutr 81: 532-534, 2005
- Risom L, Møller P, Loft S. Oxidative stress-induced DNA damage by particulate air pollution. Mutation Res 592: 119–137, 2005
- Sørensen M, Loft S, Andersen HV, Raaschou-Nielsen O, Skovgaard LT, Knudsen LE, Nielsen IV, Hertel O. Personal exposure to PM2.5, black smoke and NO2 in Copenhagen: relationship to bedroom and outdoor concentrations covering seasonal variation. J Exposure Analysis Environ Epidemiol 15: 413-22, 2005.
- Sørensen M, Schins RPF, Hertel O, Loft S. Transition metals in personal samples of PM2.5 particles and oxidative stress in human volunteers. Cancer Epidemiol Biomarker Prevention 14:1340-3, 2005
- Laskaa MJ, Nexø BA, Vistisen K, Poulsen HE, Loft S, Vogel U. Polymorphisms in RAI and in Genes of Nucleotide and Base Excision Repair are not associated with Risk of Testicular Cancer. Cancer Lett 225: 245-51, 2005
- Wellejus A, Olsen A, Tjonneland A, Thomsen BL, Overvad K, Loft S. Urinary hydroxyestrogens and breast cancer risk among postmenopausal women. Cancer Epidemiol Biomarker Prevention 14: 2137-42, 2005
- Vinzents PS, Møller P, Sørensen M, Knudsen LE, Hertel O, Jensen FP, Schibye B, Loft S. Personal Exposure to Ultrafine Particles and Oxidative DNA Damage. Environ Health Perspec 113: 1485-90, 2005
- Aarnio P, Mussalo-Rauhamaa H, Makinen-Kiljunen S, Saarela K, Loft S. Indoor air problems in a healthcare centre - A case report of a follow-up. Indoor Built Environ 14: 433-441, 2005
- Dubois J, Duez P, Kouegnigan L, Rees J-F, Loft S, Møller P, Jensen A, Poulsen H, Riis B, Weimann A, Cadet J, Douki T, Ravanat J-L, Sauvaigo S, Faure H, Morel I, Morin B, Epe B, Eckert I, Hartwig A, Schwerdtle T, Dolara P, Giovannelli L, Lodovici M, Guglielmi F, Olinski R, Bialkowski K, Foksinski M, Gackowski D, Duračková Z, Muchová J, Korytar P, Sivonová M, Dušinská M, Mislanová C, Petrovská H, Smolková B, Viña J, Lloret A, Möller L, Hofer T, Eriksson H, Gremaud E, Herbert K, Wild C, Kelly F, Dunster C, White A, Wood S, Vaughan N, Gedik CM, Andrew Collins A. Base oxidation in human lymphocyte DNA: results of an inter-laboratory validation study. FASEB J 2005; 18:82-84.
- Dragsted LO, Krath B, Ravn-Haren G, Vogel UB, Vinggaard AM, Jensen PB, Loft S, Rasmussen SE, Sandström B, Pedersen A Hermetter. Biological effects of fruit and vegetables. Proc Nutr Soc 65: 1-8, 2006
- Bak H, Autrup H, Thomsen BL, Tjonneland A, Overvad K, Vogel U, Raaschou-Nielsen, Loft S. Bulky DNA adducts as risk indicator of lung cancer in a Danish case-cohort study. Int J Cancer 118:1618-22, 2006
- Saber AT, Jacobsen NR, Bornholdt J, Kjær SL, Dybdahl M, Risom L, Loft S. Cytokine expression in mice exposed to diesel exhaust particles by inhalation - Role of tumor necrosis factor. Particle Fibre Toxicol 3:4 doi:10.1186/1743-8977-3-4, 2006
- Loft S, Risom L, Møller P. Chemical composition and surface areas in relation to health effects of ultrafine particles. Mutation Res 594: 199-200, 2006
- Ayi-Fanou L, Mobio TA, Creppy EE, Fayomi B, Fustoni S, Møller P, Kyrtopoulos S, Georgiades P, Loft S, Sanni A, Skov H, Øvrebø S, Autrup H. Markers of air pollution in Cotonou, Benin - personal monitoring and biomarkers. Sci Total Environ, 358:85-96, 2006
- Loft S, Møller P. Oxidative DNA damage and human cancer: need for cohort studies. Antioxidants Redox Signalling 8: 1021-1031, 2006
- Loft S, Svoboda P, Kasai H, Tjønneland A, Vogel U, Møller P, Overvad K, Raaschou-Nielsen O. Prospective study of 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and the risk of lung cancer. Carcinogenesis 27: 1245-1250, 2006
- Møller P, Loft S. Dietary antioxidants and beneficial effect on oxidatively damaged DNA. Free Radical Biol Med, 41: 388-415, 2006
- Johnsen NF, Christensen J, Thomsen BL, Olsen A, Loft S, Overvad K, Tjønneland A. Physical activity and risk of colon cancer in a cohort of Danish middle-aged men and women. Eur J Epidemiol 21:877–884, 2006
- Raaschou-Nielsen O, Thomsen BL, Overvad K, Tjonneland A, Vogel U, Bak H, Autrup H, Loft S. Bulky DNA adducts as risk indicators of lung cancer in a Danish case-cohort study. Int J Cancer 120: 212–213, 2007
- Löndahl J, Massling A, Pagels J, Swietlicki E, Vaclavik E, Loft S. Size-Resolved Respiratory Tract Deposition of Fine and Ultrafine Hydrophobic and Hygroscopic Aerosol Particles during Rest and Exercise. Inhalation Toxicology 19:109-16, 2007
- Sørensen M, Bisgaard H, Stage M, Loft S. Biomarkers of exposure to environmental tobacco smoke in infants. Biomarkers 12: 38-46, 2007
- Risom L, Dybdahl M, Møller P, Wallin H, Haug T, Vogel U, Klungland A, Loft S. Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice, Free Radical Res 41: 172-181, 2007
- Hansen CS, Sheykhzade M, Møller P, Folkmann JK, Amtorp O, Jonassen T, Loft S. Diesel exhaust particles induce endothelial dysfunction in apoE-/- Toxicol Appl Pharmacol 219: 24–32, 2007
- Folkmann JK, Loft S, Møller P. Oxidatively damaged DNA in aging dyslipidemic ApoE-/- and wild type mice. Mutagenesis 22: 105-110, 2007
- Tuomainen T-P, Loft S, Nyyssönen K. Punnonen K, Salonen JT, Poulsen HE. Body iron is a contributor to oxidative damage of DNA. Free Radical Res 41: 324-328, 2007
- Folkmann JK, Risom L, Hansen CS, Loft S, Møller P. Oxidatively damaged DNA and inflammation in dyslipidemic ApoE-/- mice exposed to diesel exhaust particles. Toxicology 237: 134-144, 2007
- Bräuner EV, Forchhammer L, Møller P, Simonsen J, Glasius M, Wåhlin M, Raaschou-Nielsen O, Loft S. Exposure to ultrafine particles from ambient air and oxidative stress-induced DNA damage. Environ Health Perspect 115: 1177-1182, 2007
- Loft S, Svoboda P, Kasai H, Tjønneland A, Møller P, Sørensen M. Overvad K, Autrup H, Raaschou-Nielsen O. Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: effect modification by mu class glutathione-S-transferases. Int J Cancer 121: 1579-84, 2007
- Jacobsen NR, Saber AT, Møller P, Pojana G, Vogel U, Loft S, Gingerich J, Soper L, Douglas GR, White P, Wallin H. Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of Muta™Mouse lung epithelial cells. Environ Mol Mutagenesis 48: 451-461, 2007
- Møller P, Loft S. The role of antioxidants in the prevention of oxidative damage to nucleic acids. In Oxidative Damage to Nucleic Acids, Eds. Evans MD, Cooke MS. Springer New York, USA 2007, pp. 207-223
- Risom L, Lundby C, Thomsen JJ, Mikkelsen L, Loft S, Friis G, Møller P. Acute hypoxia and reoxygenation-induced DNA oxidation in human mononuclear blood cells. Mutation Res 625: 125–133, 2007
- Risom L, Møller P, Dybdahl M, Vogel U, Wallin H, Loft S,. Dietary exposure to diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase 1 deficient mice. Toxicol Lett 175: 16-23, 2007
- Andersen ZJ, Wåhlin P, Raaschou-Nielsen, Scheike T, Loft S. Ambient Particle Source Apportionment and Daily Hospital Admissions among Children and Elderly in Copenhagen. J Exposure Sci Environ Epidemiol 17: 625-36, 2007
- Danielsen PH, Risom L. Wallin H, Autrup H, Vogel U, Loft S, Møller P. DNA damage in rats after a single oral exposure to diesel exhaust particles. Mutation Res 637: 49-55, 2008
- Hansen M, Baunsgaard D, Autrup H, Vogel U, Møller P, Lindecrona R, Wallin H, Poulsen HE, Loft S, Dragsted LO. Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome. Food Chem Toxicol 46: 752-760, 2008
- Hertel O, Solvang Jensen S, Hvidberg M, Ketzel M, Berkowicz R, Palmgren F, Wåhlin P, Glasius M, Loft S, Vinzents P, Raaschou-Nielsen O, Sørensen M, Bak H. Assessing the Impacts of Traffic Air Pollution on Human Exposure and Health. in Road Pricing, the Economy, and the Environment. Jensen-Butler C, Sloth B, Larsen MM, Madsen B, Nielsen O. pp. 277-300. Springer 2008.
- Cooke MS, Olinski R, Loft S, Evans MD, Singh R, Mistry V, Farmer PB, Rozalski R, Gackowski D, Foksinski M, Siomek A, Moller P, Danielsen P, Vaclavik E, Forchhammer L, Cadet J, Ravanat J-L, Nair J, Nair U, Poulsen HE, Weimann A, Hillestrom P. Measurement and meaning of oxidatively-modified DNA lesions in urine. Cancer Epidemiol Biomarkers Prev 17: 3-14, 2008
- Bräuner EV, Møller P. Forchhammer L. Barregard L. Gunnarsen L, Afshari A, Wåhlin P, Glasius M, Dragsted LO, Basu S, Raaschou-Nielsen O, Loft S. Indoor Particles Affect Vascular Function in the Aged: An Air Filtration-based Intervention Study. Am J Resp Critical Care Med 177: 419-25, 2008
- Hatt L, Loft S, Risom L, Møller P, Sørensen M, Raaschou-Nielsen O, Overvad K, Tjønneland A, Vogel U. OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study. Mutation Res 639: 45-54, 2008
- Guarnieri S, Loft S, Riso P, Porrini M, Risom L, Poulsen HE, Dragsted LO, Møller P. DNA repair phenotype and dietary antioxidant supplementation. Br J Nutr 99: 1018-1024, 2008
- Loft S, Bräuner EV, Forchhammer L, Pedersen M, Knudsen LE, Møller P. Complex exposures – air pollution. In Molecular Epidemiology of Chronic Disease. Eds. Wild C, Vineis P, Garte S. Wiley Press, NJ 2008, pp 343-368.
- Wellejus A, Jensen H, Loft S, Jonassen T. Expression of Aquaporin 9 in Rat Liver and Efferent Ducts of the Male Reproductive System after Neonatal Dethylstilbestrol Exposure. J Histochem Cytochem 56: 425-32, 2008
- Jacobsen NR, Møller P, Cohn CA, Loft S, Vogel U, Wallin H. Diesel exhaust particles are mutagenic in FE1-Muta™Mouse lung epithelial cells. Mutation Res 641: 54–57, 2008
- Danielsen PH, Loft S, Møller P. DNA damage and cytotoxicity in type II lung epithelial (A549) cell cultures after exposure to diesel exhaust and urban street particles. Particle Fibre Toxicol 5:6, doi:10.1186/1743-8977-5-6, 2008.
- Forchhammer L, Bräuner EV, Folkmann JK, Danielsen PH, Nielsen C, Jensen A, Loft S, Friis G, Møller P. Variation in assessment of oxidatively damaged DNA in mononuclear blood cells by the comet assay with visual scoring. Mutagenesis 23: 223-231, 2008
- Loft S, Møller P, Cooke MS, Rozalski R, Olinski R: Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker ? Eur J Nutr 47 (Suppl. 2): 19–28, 2008
- Møller P, Folkmann JK, Forchhammer L, Bräuner EV, Danielsen PH, Risom L, Loft S. Air pollution, oxidative damage to DNA and carcinogenesis. Cancer Lett 266: 84-97, 2008
- Danielsen PH, Bräuner EV, Barregard L, Sällsten G, Wallin M, Olinski R, Rozalski R, Møller P, Loft S. Oxidatively damaged DNA and its repair after experimental exposure to wood smoke in healthy humans. Mutation Res 642: 37-42, 2008
- Andersen ZJ, Wåhlin P, Raaschou-Nielsen, Ketzel M, Scheike T, Loft S. Size Distribution and Total Number Concentration of Ultrafine and Accumulation Mode Particles and Hospital Admissions in Children and the Elderly in Copenhagen, Denmark. Occup Environ Med 65: 458-66, 2008
- Jacobsen NR, Pojana G, White P, Møller P, Cohn CA, Korsholm KS, Vogel U, Marcomini U, Loft S, Wallin H. Genotoxicity, cytotoxicity and reactive oxygen species by single-walled carbon nanotubes and C60 fullerenes in the FE1-Muta™Mouse lung epithelial cells. Environ Mol Mutagenesis 49: 476-487, 2008
- Veglia F, Loft S, Matullo G, Peluso M, Munnia M, Perera F, Phillips DH, Tang D, Autrup H, Raaschou-Nielsen O, Tjønneland A, Vineis P for the Genair-EPIC investigators. DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis. Carcinogenesis 29: 932-936, 2008
- Gallo V, Khan A, Gonzales C, Phillips DH, Schoket B, Győrffy E, Anna L, Kovács K, Møller P, Loft S, Kyrtopoulos S, Matullo G, Vineis P. Validation of biomarkers for the study of environmental carcinogens: a review. Biomarkers 13: 505-534, 2008
- Andersen ZJ, Loft S, Ketzel M, Stage M, Scheike T, Hermansen MN, Bisgaard H. Ambient Air Pollution Triggers Wheezing Symptoms in Infants. Thorax 63: 710-716, 2008
- Freeese R, Dragsted LO, Loft S, Mutanen M. No effect on oxidative stress biomarkers by modified intakes of polyunsaturated fatty acids or vegetables and fruit. Eur J Clin Nutr 62:1151-1153, 2008.
- Loft S, Danielsen PH, Mikkelsen L, Risom L, Møller P. Biomarkers of oxidative damage to DNA and repair. Biochem Soc Trans 36:1071-1076, 2008
- Møller P, Risom L, Lundby C, Mikkelsen L, Loft S. Hypoxia and oxidation levels of DNA and lipids in humans and animal experimental models. IUBMB Life 60: 707-723, 2008
- Bräuner EV, Møller P, Barregard L, Glasius M, Wåhlin P, Vinzents P, Raaschou-Nielsen O, Loft S. Exposure to ambient concentrations of particulate air pollution does not influence vascular function or inflammatory pathways in young healthy individuals. Particle Fibre Toxicol 5: 13, doi:10.1186/1743-8977-5-13, 2008
- Egeberg R, Olsen A, Loft S, Christensen J, Johnsen NF, Overvad K, Tjønneland A. Intake of whole grain products and risk of breast cancer by hormone receptor status and histology among postmenopausal women. Int J Cancer 124: 745-750, 2009
- Brauner EV. Mortensen J, Møller P, Bernard A, Vinzents P, Wåhlin P, Glasius M, Loft S. Effects of Ambient Air Particulate Exposure on Blood-gas Barrier Permeability and Lung-function. Inhalation Toxicol 21: 38-47, 2009
- Saber AT, Vogel U, Loft S, Wallin H. Particle-induced Cancer. in Encyclopedia of Cancer 2nd Ed Schwab M. Springer Berlin, 2009, pp 2265-2267.
- Nørskov MS, Frikke-Schmidt R, Loft S, Tybjærg-Hansen A.. High-Throughput Genotyping of Copy Number Variation in Glutathione S-Transferases M1 and T1 using Real-Time PCR. Clinical Biochemistry 42: 201-209, 2009
- Jacobsen NR, Møller P, Jensen KA, Vogel U, Ladefoged O, Loft S, Wallin H. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice. Particle Fibre Toxicol 6: 2, 2009
- Danielsen PH, Loft S, Kocbach A, Schwarze PE, Møller P. Oxidative damage to DNA and repair induced by Norwegian wood smoke particles in human A549 and THP-1 cell lines. Mutation Res 674: 116-122, 2009
- Sørensen LT, Jørgensen S, Petersen LJ, Hemmingsen U, Bülow J, Loft S, Gottrup F. Acute effects of nicotine and smoking on blood flow, tissue oxygen and aerobe metabolism of the skin and subcutis. J Surg Res152: 224-30, 2009
- Vesterdal LK, Folkmann JF, Jacobsen NR, Sheykhzade M, Wallin H, Loft S, Møller P. Modest vasomotor dysfunction induced by C60 fullerenes in apolipoprotein E knockout mice with different degree of atherosclerosis. Particle Fibre Toxicol 6:5, 2009 doi:10.1186/1743-8977-6-5
- Folkmann JK, Risom L, Jacobsen NR, Wallin H, Loft S, Møller P. Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-walled Carbon Nanotubes. Environ Health Perspect 117:703–708, 2009
- Hansen RD, Krath BN, Frederiksen K, Tjønneland A, Overvad K, Roswall N, Loft S, Dragsted LO, Vogel U, Raaschou-Nielsen O.GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer. Mutation Res 664: 13–19, 2009
- Saber AT, Halappanavar S, Folkmann JF, Bornholdt J, Boisen AM, Møller P, Williams A, Yauk C, Vogel U, Loft S, Wallin H. Lack of acute phase response in the liver of mice exposed to diesel exhaust particles and carbon black by inhalation. Particle Fibre Toxicol 6: 12, 2009
- Johnsen NF, Tjønneland A, Thomsen BL, Christensen J, Loft S, Friedenreich C, Key TJ, Allen NE, Lahmann PH, Mejlvig L, Overvad K, Kaaks R, Rohrmann S, Boing H, Misirli G, Trichopoulou A, Zylis D, Tumino R, Pala V, Bueno-de-Mesquita HB, Kiemeney LA, Suárez LR, Gonzalez CA, Sánchez M-J, Huerta JM, Gurrea AB, Manjer J, Wirfält E, Khaw K-T, Wareham N, Boffetta P, Egevad L, Rinaldi S, Riboli E. Physical activity and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Int J Cancer 125: 902-8, 2009
- Löndahl J, Massling A, Bräuner, EV, Swietlicki E, Ketzel M, Pagels J, Loft S. Experimentally Determined Human Respiratory Tract Deposition of Airborne Particles at a Busy Street. Environ Sci Tech 43: 4659–64, 2009
- Mikkelsen L, Bialkowski K, Risom R, Loft S, Moller P. Aging and defence against generation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA. Free Radical Biol Med 47: 608-15, 2009
- Sørensen M, Allermann L, Vogel U, Andersen PS, Jespersgaard C, Loft S, Raaschou-Nielsen O. Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children. Pediatric Allergy Immunol 20: 614-23, 2009
- Egeberg R, Frederiksen K, Olsen A, Johnsen NF, Loft S, Overvad K, Tjønneland A. Intake of whole grain products is associated with dietary, lifestyle, anthropometric and socioeconomic factors in Denmark. Public Health Nutr 12:1519-30, 2009
- Hemmingsen JG, Hougaard KS, Talsness C, Wellejus A, Loft S, Wallin H, Møller P. Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in mice. Toxicology 264: 61-68, 2009
- Loft S. Luftkvalitet og klimaforandringer. Ugeskr f Læger 171: 3168-71, 2009
- Pedersen M, Wichmann J, Autrup H, Dang DA, Hvidberg M, Bossi R, Jakobsen J, Loft S, Knudsen LE. Increased micronuclei and bulky DNA adducts in cord blood after maternal exposures to traffic-related air pollution. Environ Res 109: 1012-20, 2009
- Aitken R, Borm P, Donaldson K, Ichihara G, Loft S, Marano F, Maynard A, Oberdörster G, Stamm H, Stone V, Tran L, Wallin H. Nanoparticles:- one word: a multiplicity of different hazards. Nanotoxicology 3: 263-4, 2009.
- Møller P, Jacobsen NR, Folkmann J, Danielsen P, Mikkelsen L, Hemmingsen J, Vesterdal L, Forchhammer L, Wallin H, Loft S. Role of oxidative damage in toxicity of particulates. Free Radical Res 44: 1-46, 2010
- Johnsen NF, Olsen A, Thomsen BLR, Christensen J, Egeberg R, Knudsen KEB, Loft S, Overvad K, Tjønneland A. Plasma enterolactone and risk of colon and rectal cancer in a case-cohort study of Danish men and women. Cancer Causes Control 21:153-162, 2010
- Raaschou-Nielsen O, Hermansen MN, Loland L. Buchwald F, Pipper CB, Sørensen M, Loft S, Bisgaard H. Long-term exposure to indoor air pollution and wheezing symptoms in infants. Indoor Air 20: 159-167, 2010
- Forchhammer L, Johansson C, Loft S, Möller L, Godschalk R, Langie S, Jones G, Kwok R, Oscoz A, Collins A, Phillips D, Brookes L, Sozeri O, Stepnik M, Palus J, Vogel U, Wallin H, Routledge M, Handforth C, Allione A, Møller P. Variation in the measurement of DNA damage by comet assay measured by the ECVAG inter-laboratory validation trial. Mutagenesis 25: 113-23, 2010
- Johansson C, Møller P, Forchhammer L, Loft S, Godschalk RW, Langie S, Lumeij S, Jones GD, Kwok RW, Oscoz AA, Phillips DH, Sozeri O, Routledge MN, Handforth C, Riso P, Porrini M, Allione A, Matullo G, Palus J, Stepnik M, Collins AR, Möller L. An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay. Mutagenesis 25:125-32, 2010
- Eriksen KT. Sørensen M, Autrup H, Vogel U, Overvad K, Tjønneland A, Loft S, Raaschou-Nielsen O, Life-style, environmental, and genetic predictors of bulky DNA adducts in a study population nested within a prospective Danish cohort. J Toxicol Environ Health 73: 583-595, 2010
- ESCULA [European Standards Committee on Urinary (DNA) Lesion Analysis], Evans MD, Olinski R, Loft S, Cooke MS. Towards consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a non-invasive biomarker of oxidative stress. FASEB J 24:1249-60, 2010
- Pedersen M, Halldorsson TI, Mathiesen L, Mose T, Brouwer A, Hedegaard M, Loft S, Kleinjans JSC, Besselink H, Knudsen LE. Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs.. Environment Int 36: 344-51, 2010
- Møller P, Lohr M, Folkmann JK, Mikkelsen L, Loft S. Aging and oxidatively damaged nuclear DNA in animal organs. Free Radicals Biol Med 48: 1275-85, 2010
- Cooke M, Loft S, Olinski R, Evans M, Bialkowski K, Wagner J, Dedon P, Møller P, Greenberg M, Cadet J. Recommendations for standardised description of, and nomenclature concerning, oxidatively damaged nucleobases in DNA. Chem Res Toxicol 23: 705-707, 2010
- Raaschou-Nielsen O, Bak H, Sørensen M, Jensen SS, Ketzel M, Hvidberg M, Schnohr P, Tjønneland A, Overvad K, Loft S. Air pollution from traffic and risk for lung cancer in three Danish cohorts. Cancer Epidemiol Biomarker Prev 19:1284-91, 2010
- Eriksen KT, Raaschou-Nielsen O, Sørensen M, Roursgaard M, Loft S, Møller P. Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells. Mutation Res 700: 39-43, 2010
- Andersen Z, Olsen TS, Andersen KK, Loft S, Ketzel M, Raaschou-Nielsen O. Association between short-term exposure to ultrafine particles and hospital admissions for stroke in Copenhagen, Denmark. Eur Heart J 31: 2034-40, 2010
- Møller P, Loft S. Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution. Environ Health Perspec 118: 1126-36, 2010
- Egebjerg R, Olsen A, Loft S, Christensen J, Johnsen NF, Overvad K, Tjønneland A. Intake of wholegrain products and risk of colon and rectal cancer – results from the Diet, Cancer and Health cohort study. Br J Cancer 103: 730-4, 2010
- Löndahl J, Swietlicki E, Lindgren E, Loft S. Aerosol exposure versus aerosol cooling of climate: What is the optimal emission reduction strategy for human health. Atmospheric Chem Phys 10, 9441–9449, 2010
- Riso P, Martini D, Møller P, Loft S, Bonacina G, Moro M, Porrini M.DNA damage and repair activity after broccoli intake in young healthy smokers. Mutagenesis 25: 595-602, 2010
- Danielsen PH, Loft S, Jacobsen NR, Jensen KA, Autrup H, Ravanat JL, Wallin H, Møller P. Oxidative stress, inflammation and DNA damage in rats after intratracheal instillation or oral exposure to ambient air and wood smoke particulate matter. Toxicol Sci 118: 574-585, 2010
- Vesterdal LK, Folkmann JK, Jacobsen NR, Sheykhzade M, Wallin H, Loft S, Møller P. Pulmonary exposure to carbon black nanoparticles and vascular effects. Particle Fibre Toxicol 7: 33, 2010
- Ricceri F, Godschalk R, Peluso M, Phillips D, Agudo A, Georgiadis P, Loft S, Tjønneland A, Raaschou-Nielsen O, Palli D, Perera F, Vermeulen R, Taioli E, Sram RJ, Rosa F, Allione A, Matullo G, Vineis P. Bulky DNA adducts in white-blood cells: a pooled analysis of 3600 subjects. Cancer Epidemiol Biomarkers Prev 19: 3174-81, 2010
- Andersen ZJ, Hvidberg M, Jensen SS, Ketzel M, Loft S, Sørensen M, Tjønneland A, Overvad K, Raaschou-Nielsen O. Chronic obstructive pulmonary disease and long-term exposure to traffic-related air pollution: a cohort study. Am J Resp Crit Care Med 183: 455-61, 2011
- Danielsen PH, Møller P, Jensen KA, Sharma AK, Wallin H, Bossi R, Autrup H, Mølhave L, Ravanat JL, Briedé J, de Kok T, Loft Oxidative stress, DNA damage and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines. Chem Res Toxicol 24:168-184, 2011
- Loft S, Schins RPF, Møller P. Particulates and oxidative stress. In Cardiovascular Effects of Inhaled Fine and Nano-sized Particles. Eds. Cassee FR, Mills NL, Newby DE. Pp. 251-271. John Wiley & Sons, Inc, NJ, US. 2011.
- Paulsen M, Frikke-Scmidt R, Nordestgaard BG, Loft S, Tybjaerg-Hansen A. Copy number variation in glutathione S-transferase T1 and risk of prostate and corpus uteri cancer in the general population. Pharmacogenomics J 11: 292-299, 2011
- Møller P, Mikkelsen L, Vesterdal L, Folkmann JK, Forchhammer L, Roursgaard M, Danielsen PH, Loft S. Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis. Crit Rev Toxicol 41: 339-68, 2011
- Raaschou-Nielsen O, Andersen Z, Hvidberg M, Jensen SS, Ketzel M, Sørensen M, Loft S, Overvad K, Tjønneland A. Lung Cancer Incidence and Long-Term Exposure to Air Pollution from Traffic. Environ Health Perspect 119: 860-865, 2011
- Frikke-Schmidt H, Roursgaard M, Lykkesfeldt J, Loft S, Nøjgaard JK, Møller P. Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells. Tox Lett 203:181-189, 2011
- Egeberg R, Olsen A, Christensen J, Johnsen NF, Loft S, Overvad K, Tjønneland A. Intake of whole grain products and risk of prostate cancer among men in the Danish Diet, Cancer and Health cohort study. Cancer Cause Control 22:1133-9, 2011
- Wichmann J, Andersen Z, Ketzel M, Ellermann T, Loft S. Apparent temperature and cause-specific emergency hospital admissions in Greater Copenhagen, Denmark. PLoS ONE 6: e22904, 2011
- Nørskov MS, Frikke-Schmidt R, Loft S, Sillesen H, Grande P, Nordestgaard BG, Tybjærg-Hansen A. Copy Number Variation in Glutathione S-transferases M1 and T1 and Ischemic Vascular Disease: Four Studies and Meta-analyses. Circ Cardiovasc Genet 4: 418-28, 2011
- Raaschou-Nielsen O, Andersen JZ, Hvidberg M, Jensen SS, Ketzel M, Sørensen M, Hansen J, Loft S, Overvad K, Tjønneland A. Air pollution from traffic and cancer incidence in a Danish cohort. Environmental Health 10:67, 2011
- Wichmann J, Andersen Z, Ketzel M, Ellermann T, Loft S. Apparent temperature and cause-specific mortality in Copenhagen, Denmark: a case-crossover analysis. Int J Environ Res Public Health 8: 3712-3727, 2011
- Hemmingsen JG, Møller P, Nøjgaard JK, Roursgård M, Loft S. Oxidative stress, genotoxicity, and vascular cell adhesion molecule expression in cells exposed to particulate matter from combustion of conventional diesel and methyl ester biodiesel blends. Environ Sci Tech 45: 8545-51, 2011
- Mikkelsen L, Sheykhzade M, Jensen KA, Saber AT, Jacobsen NR, Vogel U, Wallin H, Loft S, Møller P. Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2. Particle Fibre Toxicol 8: 32-, 2011
- Loft S, Møller P. Oxidative Stress to DNA and Lipids – Relation to Air Pollution. In Biomarkers and Human Biomonitoring 2: Selected Biomarkers of Current Interest, eds. Knudsen LE, Merlo DF. Royal Society of Chemistry, 160-173, 2012.
- Petersen RK, Larsen SB, Jensen DM, Christensen J, Olsen A, Loft S, Nellemann C, Overvad K, Kristiansen K, Tjønneland A, Vogel U. PPARgamma-PGC-1alpha activity is determinant of alcohol related breast cancer. Cancer Lett 315: 59-68, 2012
- Andersen ZJ, Bønnelykke K, Hvidberg M, Jensen SS, Ketzel M, Loft S, Sørensen M, Tjønneland A, Overvad K, Raaschou-Nielsen O. Long-term exposure to air pollution and asthma hospitalizations in elderly adults: a cohort study. Thorax 67: 6-11, 2012
- Andersen ZJ, Raaschou-Nielsen O, Carstensen B, Hvidberg M, Jensen SS, Ketzel M, Loft S, Tjønneland A, Overvad K, Sørensen M. Diabetes incidence and long-term exposure to air pollution: a cohort study. Diabetes Care 35: 92-98, 2012
- Jensen A, Løhr M, Eriksen L, Grønbæk M, Dorry E, Loft S, Møller P. Influence of the OGG1 Ser326Cys polymorphism on oxidatively damaged DNA and repair activity. Free Radical Biol Med 52: 118-125, 2012
- Loft S, Svoboda P, Kawai K, Kasai K, Sørensen M, Tjønneland A, Vogel U, Møller P, Overvad K, Raaschou-Nielsen O. Association between 8-oxo-7,8-dihydro-guanine excretion and risk of lung cancer in a prospective study. Free Radical Biol Med 52: 167-72, 2012
- Bräuner EV, Loft S, Raaschou-Nielsen O, Vogel U, Skytt Andersen P, Sørensen M. Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze. Genes Immunity 13: 94-7, 2012
- Forchhammer L, Loft S, Roursgaard M, Cao Y, Riddervold IS, Sigsgaard T, Moller P. Expression of adhesion molecules, monocyte interactions and oxidative stress in human endothelial cells exposed to wood smoke and diesel exhaust particulate matter. Toxicol Lett 209: 121-8, 2012
- Andersen, ZJ, Kristiansen LC, Andersen KK, Olsen TS, Hvidberg M, Jensen SS, Ketzel M, Loft S, Sørensen M, Tjønneland A, Overvad K, Raaschou-Nielsen O. Stroke and long-term exposure to outdoor air pollution from NO2: a cohort study. Stroke 43: 320-5, 2012
- Loft S, Danielsen PH, Løhr M, Jantzen K, Hemmingsen JG, Roursgaard M, Karotki DG, Møller P. Urinary excretion of 8-oxo-7,8-dihydroguanine as biomarker of oxidative damage to DNA. Arch Biochem Biophys 518: 142-50, 2012
- Cadet J, Loft S, Olinski R, Evans MD, Bialkowski K, Wagner R, Dedon PC, Møller P, Greenberg MM, Cooke MS. Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radical Res 46: 367-81. 2012
- Møller P, Cooke MS, Collins A, Olinski R, Rozalski R, Loft S. Harmonising measurements of oxidatively damaged DNA. Free Radical Res 46: 541-53, 2012
- Bourdon JA, Saber AT, Jacobsen NR, Jensen KA, Madsen AM, Lamson JS, Wallin H, Møller P, Loft S, Yauk CL, Vogel UB. Carbon Black Nanoparticle Instillation Induces Sustained Inflammation and Oxidative Stress-Related Genotoxicity in Mouse Lung and Liver. Particle Fibre Toxicol 9: 5, 2012
- Leijnse N, Jeon JH, Loft S, Metzler R, Oddershede LB. Diffusion inside living human cells. Eur Phys J 204: 75-84, 2012
- Forchhammer L, Møller P, Riddervold IS, Bønløkke J, Massling A, Sigsgaard T, Loft S. Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function. Particle Fibre Toxicol 9: 7, 2012
- Wichmann J, Ketzel M, Ellermann T, Loft Apparent temperature and acute myocardial infarction hospital admissions in Copenhagen, Denmark: A case-crossover study. Environ Health. 11: 19, 2012
- Saber AT, Jensen KA, Jacobsen NR, Birkedal R, Mikkelsen L, Møller P, Loft S, Wallin H, Vogel U. Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers. Nanotoxicology 6: 453-71, 2012
- Pedersen M, Halldorsson TI, Autrup H, Brouwer A, Besselink H, Loft S, Knudsen LE. Maternal diet and dioxin-like activity, bulky DNA adducts and micronuclei in mother-newborns. Mutat Res 734: 12-9, 2012
- Jackson PJ, Hougaard KS, Boisen AZ, Jacobsen NR, Jensen KA, Peter Møller, Brunborg G, Gutzkow KB, Andersen O, Loft S, Vogel U, Wallin H. Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring. Nanotoxicology 6: 453-71, 2012
- Demetriou C, Raaschou-Nielsen O, Loft S, Møller P, Vermeulen R, Palli D, Chadeau-Hyam M, Xun WW, Vineis P. Biomarkers of ambient air pollution and lung cancer: strength of evidence. Occup Environ Med 69: 619-27, 2012
- Folkmann JK, Vesterdal LK, Sheykhzade M, Loft S, Møller P. Endothelial dysfunction in normal and prediabetic rats with metabolic syndrome exposed by oral gavage to carbon black nanoparticles. Toxicol Sci 129:98-107, 2012.
- Vesterdal LK, Mikkelsen L, Folkmann JF, Sheykhzade M, Cao Y, Roursgaard M, Loft S, Møller P. Carbon black nanoparticles and vascular dysfunction in cultured endothelial cells and aorta segments. Tox Lett 214: 19-26, 2012
- Saber AT, Koponen IK, Jensen KA, Jacobsen NR, Mikkelsen L, Møller P, Loft S, Vogel U, Wallin H. Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers. Nanotoxicology 6: 778-88, 2012
- Jantzen K, Roursgaard M, Madsen CD, Loft S, Rasmussen LJ, Møller P. Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human macrophages and lung epithelial cells. Mutagenesis 27: 693-701, 2012
- Forchhammer L, Ersson C, Loft S, Möller L, Godschalk RWL, van Schooten FJ, Jones GDD, Higgins JA, Cooke MS, Mistry V, Karbaschi M, Collins AR, Azqueta A, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, Matullo G, Allione A, Stepnik M, Komorowska M, Teixeira JP, Costa S, Corcuera LA, López de Cerain A, Laffon B, Valdiglesias V, Møller P. Inter-laboratory variation in DNA damage using a standard comet assay protocol. Mutagenesis 27: 665-72, 2012
- Møller P, Folkmann JK, Danielsen P, Jantzen K, Loft S. Oxidative stress generated damage to DNA by gastrointestinal exposure to insoluble particles. Curr Mol Med 12: 732-45, 2012
- Raaschou-Nielsen O, Andersen ZJ, Jensen SS, Ketzel M, Sørensen M, Hansen J, Loft S, Tjønneland A, Overvad K. Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study. Environ Health 11: 60, 2012
- Johnston H, Pojana G, Zuin S, Jacobsen NR, Møller P, Loft S, Semmler-Behnke M, McGuiness C, Balharry D, Marcomini A, Wallin H, Kreyling W, Donaldson K, Tran L, Stone V. Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges. Crit Rev Toxicol 43: 1-20, 2013
- Jorgensen A, Maigaard K, Wörtwein G, Hageman I, Henriksen T, Weimann A, Møller P, Loft S, Hau J, Poulsen HE, Jorgensen MB. Chronic restraint stress in rats causes sustained increase in urinary corticosterone excretion without cerebral or systemic oxidatively generated DNA/RNA damage. Progr Neuro-Psychopharmacol Biol Psych 40: 30-37, 2013
- Raaschou-Nielsen O, Sørensen M, Ketzel M, Hertel O, Loft S, Tjønneland A, Overvad K, Andersen ZJ. Long-term exposure to traffic air pollution and diabetes-related mortality: a cohort study. Diabetologia 56: 36-46, 2013
- Møller P, Danielsen PH, Jantzen K, Roursgaard M, Loft S. Oxidatively damaged DNA in animals exposed to particles. Crit Rev Toxicol 43: 96-118, 2013
- Wichmann J, Folke F, Torp-Pedersen C, Lippert F, Ketzel M, Ellermannd T, Loft S. Out-of-hospital cardiac arrests and outdoor air pollution exposure in Copenhagen, Denmark. PLoS One 8: e53684, 2013, doi:10.1371/journal.pone.0053684
- Mikkelsen L, Jensen KA, Koponen IK, Saber AT, Wallin H, Loft S, Vogel U, Møller P. Oxidative stress and expression of adhesion molecules in human umbilical vein endothelial cells exposed to nanoparticle-containing paint dusts. Nanotoxicology 7: 117-34, 2013
- Del Bo’ C, Riso P, Campolo J, Møller P, Loft S, Klimis-Zacas D, Brambilla A, Rizzolo A, Porrini M, A single portion of blueberry (Vaccinium corymbosum L.) improves protection against DNA damage but not vascular function in healthy male volunteers. Nutr Res 33: 220-7, 2013
- Kyrø C, Skeie G, Loft S, Overvad K, Christensen J, Tjønneland A, Olsen A. Adherence to a healthy Nordic food index is associated with a lower risk of colorectal cancer – The Danish Diet, Cancer and Health cohort study. Br J Nutrition 109: 920-7, 2013
- Riso P, Klimis-Zacas D, Del Bo’ C, Martini D, Campolo J, Vendrame S, Møller P, Loft S, De Maria R, Porrini M. Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors. Eur J Nutr 52: 949-61, 2013
- Dallal CM, Stone RA, Cauley JA, Ness RB, Vogel VG, Fentiman IS, Fowke JH, Krogh V, Loft S, Meilahn EN, Muti P, Olsen A, Overvad K, Sieri S, Tjønneland A, Ursin G, Wellejus A, Taioli E. Urinary estrogen metabolites and breast cancer: a combined analysis of individual level data. Int J Biol Markers 28:e3-e16, 2013
- Barregard L, Møller P, Henriksen T, Mistry V, Koppen G, Rossner P, Sram RJ, Weimann A, Poulsen HE, Nataf R, Andreoli R, Manini P, Marczylo TH, Lam P, Evans MD, Kasai H, Kawai K, Li YS, Sakai K, Singh R, Teichert F, Farmer PB, Rozalski R, Gackowski D, Siomek A, Saez GZ, Cerda C, Broberg K, Lindh K, Hossain MB, Haghdoost S, Hu CW, Chao MR, Wu KY, Orhan H, Senduran N, Smith RJ, Santella RM, Su Y, Cortez C, Yeh S, Olinski R, Loft S, Cooke MS. Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2’-deoxyguanosine. Antioxidants Redox Signal 18: 2377-91, 2013
- Ersson C, Møller P, Forchhammer L, Loft S, Azqueta A, Godschalk RWL, van Schooten FJ, Jones GDD, Higgins JA, Cooke MS, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, Matullo G, Allione A, Stępnik M, Ferlińska M, Teixeira JP, Costa S, Corcuera LA, de Cerain AL, Laffon B, Valdiglesias V, Collins AR, Möller L. An ECVAG inter-laboratory validation study of the comet assay:inter- and intra-laboratory variation of DNA strand breaks and FPG-sensitive sites in human mononuclear cells. Mutagenesis 28: 279-86, 2013
- Kyrø C, Skeie G, Loft S, Landberg R, Christensen J, Lund E, Nilsson LM, Palmqvist R, Tjønneland A, Olsen A. Intake of whole grains from different cereal- and food sources and incidence of colorectal cancer in the Scandinavian HELGA cohort. Cancer Causes Control 24: 1363-74, 2013
- Loft S, Olsen A, Møller P, Poulsen HE, Tjønneland A. Association between 8-oxo-7,8-dihydro-2’-deoxyguanosine excretion and risk of postmenopausal breast cancer: nested case-control Cancer Epidemiol Biomarker Prev 22: 1289-96, 2013
- Godschalk RWL, Ersson C, Riso P, Porrini M, Langie SAS, van Schooten FJ, Azqueta A, Collins AR, Jones GDD, Kwok RWL, Phillips DH, Sozeri O, Allione A, Matullo G, Möller L, Forchhammer L, Loft S, Møller P. DNA repair measurements using the modified comet assay: an inter-laboratory comparison within the European Comet Assay Validation Group (ECVAG). Mutation Res 757: 60-7, 2013
- Bräuner EV, Andersen ZJ, Andersen CE, Pedersen C, Gravesen P, Ulbak K, Hertel O, Loft S, Raaschou-Nielsen O. Residential Radon and Brain cancer Incidence in a Danish Cohort. PLoS One 8:e744, 2013
- Hertel O, Jensen SS, Ketzel M, Becker T, Peel RG, Ørby PV, Skjøth CA, Ellerman T, Raaschou-Nielsen O, Sørensen M, Brauner EV, Andersen ZJ, Loft S, Bønløkke JH, Sigsgaard T. Utilizing Monitoring Data and Spatial Analysis Tools for Exposure Assessment of Atmospheric Pollutants in Denmark, pp 95-122 in Occurrence, Fate and Impact of Atmospheric Pollutants on Environmental and Human Health. Eds. McConnell LL, Dachs J, Hapeman CJ. American Chemical Society Symposium Series 2013. DOI: 10.1021/bk-2013-1149
- Beko G, Weschler CJ, Wierzbicka A, Karottki DG, Toftum J, Loft S, Clausen G Ultrafine particles: Exposure and source apportionment in 56 Danish homes. Environ Sci Technol 47: 10240-8, 2013
- Karottki DG, Spilak M, Frederiksen M, Gunnarsen L, Brauner EV, Kolarik B, Andersen ZJ, Sigsgaard T, Barregard L, Strandberg B, Sallsten G, Møller P, Loft S. An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter. Environ Health 12:116, 2013
- Domijan AM, Miletić-Medved M, Peraica M, Loft S. Malondialdehyde and 8-oxo-7.8-dihydro-2'deoxyguanosine in the urine of residents from Balkan endemic nephropathy area in Croatia--a pilot study. Coll Antropol 37:1195-8, 2013
- Vesterdal LK, Danielsen PH, Folkmann JK, Jespersen L, Aguilar-Pelaez K, Roursgaard M, Loft S, Møller P. Accumulation of lipids and oxidatively damaged DNA in hepatocytes exposed to particles. Toxicol Appl Pharmacol 274: 350-60, 2014
- Spilak M, Karottki DG, Frederiksen M, Kolarik B, Loft S Gunnarsen L. Evaluation of building characteristics in 27 dwellings in Denmark and effect of using particle filtration units on PM2.5 concentrations. Building Environ 73: 55-63, 2014
- Vesterdal LK, Jantzen K, Sheykhzade M, Roursgaard M, Folkmann JK, Loft S, Møller P. Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in apoE-/-mice. Nanotoxicology 8: 61-71, 2014
- Kyrø C, Olsen A, Landberg R, Skeie G, Loft S, Aman P, Leenders M, Dik VK, Siersema PD, Pischon T, Christensen J, Overvad K, Boutron-Ruault MC, Fagherazzi G, Cottet V, Kühn T, Chang-Claude J, Boeing H, Trichopoulou A, Bamia C, Trichopoulos D, Palli D, Krogh V, Tumino R, Vineis P, Panico S, Peeters PH, Weiderpass E, Bakken T, Asli LA, Argüelles M, Jakszyn P, Sánchez MJ, Amiano P, Huerta JM, Barricarte A, Ljuslinder I, Palmqvist R, Khaw KT, Wareham N, Key TJ, Travis RC, Ferrari P, Freisling H, Jenab M, Gunter MJ, Murphy N, Riboli E, Tjønneland A, Bueno-de-Mesquita HB. Plasma Alkylresorcinols, Biomarkers of Whole-Grain Wheat and Rye Intake, and Incidence of Colorectal Cancer. J Natl Cancer Inst 106: djt352, 2014
- Cao Y, Jacobsen NR, Danielsen PH, Lenz AG, Stoeger T, Loft S, Wallin H, Roursgaard M, Mikkelsen L, Møller P. Vascular effects of multi-walled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells.. Toxicol Sci 138:104-16, 2014
- Bräuner EV, Loft S, Wellejus A, Autrup H, Tjønneland A, Raaschou-Nielsen O. Adipose tissue PCB levels and CYP1B1 and COMT genotypes in relation to breast cancer risk in postmenopausal Danish women. Int J Environ Health Res 24: 256-68, 2014
- Kyrø C, Olsen A, Bueno-de-Mesquita HB, Skeie G, Loft S, Aman P, Leenders M, Dik VK, Siersema PD, Pischon T, Christensen J, Overvad K, Boutron-Ruault MC, Fagherazzi G, Cottet V, Kühn T, Chang-Claude J, Boeing H, Trichopoulou A, Naska A, Oikonomidou D, Masala G, Pala V, Tumino R, Vineis P, Mattiello A, Peeters PH, Bakken T, Weiderpass E, Asli LA, Sánchez S, Jakszyn P, Sánchez MJ, Amiano P, Huerta JM, Barricarte A, Ljuslinder I, Palmqvist R, Khaw KT, Wareham N, Key TJ, Travis RC, Slimani N, Freisling H, Ferrari P, Gunter MJ, Murphy N, Riboli E, Tjønneland A, Landberg R. Plasma alkylresorcinol concentrations, biomarkers of whole-grain wheat and rye intake, in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Br J Nutr 111: 1881-90, 2014
- Jensen A, Karottki DG, Christensen JM, Bønløkke JH, Sigsgaard T, Glasius M, Loft S, Møller P. Biomarkers of oxidative stress and inflammation after wood smoke exposure in a reconstructed Viking Age house. Environ Mol Mutagenesis 55: 652-61, 2014
- Rissler J, Nordin EZ, Eriksson AC, Nilsson PT, Frosch M, Sporre MK, Wierzbicka A, Svenningsson B, Löndahl J, Messing ME, Sjogren S, Hemmingsen JG, Loft S, Pagels JH, Swietlicki E. Effective density and mixing state of aerosol particles in a near-traffic urban environment. Environ Sci Technol 48: 6300-8, 2014
- Godschalk RW, Ersson C, Stępnik M, Ferliłska M, Palus J, Teixeira JP, Costa S, Jones GD, Higgins JA, Kain J, Möller L, Forchhammer L, Loft S, Lorenzo Y, Collins AR, van Schooten FJ, Laffon B, Valdiglesias V, Cooke M, Mistry V, Karbaschi M, Phillips DH, Sozeri O, Routledge MN, Nelson-Smith K, Riso P, Porrini M, López de Cerain A, Azqueta A, Matullo G, Allione A, Møller P. Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories. Mutagenesis 29: 241-9, 2014
- Møller P, Loft P, Ersson C, Koppen G, Dusinska M, Collins A. On the search for an intelligible comet assay descriptor. Frontiers Genetics 5: 217, 2014
- Roursgaard M, Jensen KA, Danielsen PH, Mikkelsen LÆ, Folkmann JK, Forchammer L, Jantzen K, Klingberg H, Cao Y, Loft S, Møller P. User-dependent variability in validation of size determination of nanoparticles in suspension by means of Nanoparticle Tracking Analysis (NTA) software from NanoSight. Adv Sci Engineer Med 6, 931-41, 2014
- Bräuner EV, Nordsborg EB, Andersen ZJ, Tjønneland A, Loft S, Raaschou-Nielsen O, Long-Term Exposure to Low-Level Arsenic in Drinking-Water and Diabetes Incidence: A Prospective Study of the Diet, Cancer and Health Cohort. Environ Health Perspec 122: 1059-65, 2014
- Karottki DG, Bekö G; Clausen G; Madsen AM; Andersen ZJ; Massling A; Ketzel M; Ellermann T; Lund R; Sigsgaard T; Møller P; Loft S. Cardiovascular and lung function in relation to outdoor and indoor exposure to fine and ultrafine particulate matter in middle-aged subjects. Environ Int 73: 372-381, 2014
- Møller KL, Thygesen LC, Schipperijn J, Loft S, Bonde JP, Mikkelsen S, Brauer C. Occupational exposure to ultrafine particles among airport employees - Combining personal monitoring and Global Positioning System. PLoS One. 9: e106671, 2014
- Cao Y, Roursgaard M, Danielsen PH, Møller P, Loft S. Carbon black nanoparticles promote endothelial activation and lipid accumulation in macrophages independently of intracellular ROS production. PLoS One 9: e10671, 2014
- Møller P, Loft S. Statistical analysis of comet assay results. Frontiers Genetics 5:292, 2014
- Møller P, Christophersen DV, Jensen DM, Kermanizadeh A, Roursgaard M, Jacobsen NR, Hemmingsen JG, Danielsen PH, Cao Y, Jantzen K, Klingberg H, Hersoug LG, Loft S. Role of oxidative stress in carbon nanotube generated health effects. Arch Toxicol 88: 1939-64, 2014
- Møller P, Danielsen PH, Karottki DG, Jantzen K, Roursgaard M, Klingberg H, Jensen DM, Christophersen DV, Hemmingsen JG, Cao Y, Loft S. Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles. Mutation Res Reviews 762; 133-66, 2014
- Kermanizadeh A, Løhr M, Roursgaard M, Messner S, Gunness P, Kelm JM, Møller P, Stone V, Loft S. Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model. Particle Fibre Toxicol 11:56, 2014
- Olsen Y, Karottki DG, Jensen DM, Bekö G, Kjeldsen BU, Clausen G, Hersoug LG, Holst GJ, Wierzbicka A, Sigsgaard T, Linneberg A, Møller P, Loft S. Vascular and lung function related to ultrafine and fine particles exposure assessed by personal and indoor monitoring: a cross-sectional study. Environ Health 13: 112, 2014
- Maynard S, Keijzers G, Hansen ÅM, Osler M, Molbo D, Bendix L, Møller P, Loft S, Moreno-Villanueva M, Bürkle A, Hvitby GP, Schurman SH, Stevnsner T, Rasmussen LJ, Avlund K, Bohr VA. Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance. Acta Physiol 213: 156-70, 2015
- Møller P, Hemmingsen JG, Jensen DM, Danielsen PH, Karottki DG, Jantzen K, Roursgaard M, Cao Y, Kermanizadeh A, Klingberg H, Christophersen DV, Hersoug LG, Loft S. Applications of the comet assay in particle toxicology: air pollution and engineered nanomaterials exposure. Mutagenesis 30: 67-83, 2015
- Knudsen KB, Northeved H, Kumar P, Permin A, Andresen TL, Larsen S, Wegener KM, Lykkesfeldt J, Jantzen K, Loft S, Møller P, Roursgaard M. In vivo toxicity of cationic micelles and liposomes. Nanomedicine 11: 467-77, 2015
- Møller P, Jensen DM, Christophersen DV, Kermanizadeh A, Jacobsen NR, Hemmingsen JG, Danielsen PH, Karottki DG, Roursgaard M, Cao Y, Jantzen K, Klingberg H, Hersoug LG, Loft S. Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals. Environ Mol Mutagen 56: 97-110, 2015
- Karottki DG, Spilak M, Frederiksen M, Andersen ZJ, Madsen AM, Ketzel M, Massling A, Gunnarsen L, Møller P, Loft S. Indoor and Outdoor Exposure to Ultrafine, Fine and Microbiologically Derived Particulate Matter Related to Cardiovascular and Respiratory Effects in a panel of Elderly Urban Citizens. Int J Eviron Res Public Health. 12:1667-86, 2015
- Cao Y, Roursgaard M, Kermanizadeh A, Loft S, Møller P. Synergistic effects of zinc oxide nanoparticle and fatty acid on toxicity to Caco-2 cells. Int J Toxicol 34: 67-76, 2015
- Kermanizadeh A, Chauché C, Brown DM, Loft S, Møller P. The role of intracellular redox imbalance in nanomaterial induced cellular damage and genotoxicity - a review. Environ Mol Mutagen 56: 111-24, 2015
- Løhr M, Jensen A, Eriksen L, Grønbæk M, Loft S, Møller P. Age and metabolic risk factors associated with oxidative damage to DNA in human peripheral blood mononuclear cells. Oncotarget 6:2641-2653, 2015
- Forsberg K, Aalling N, Wörtwein G, Loft S, Møller P, Hau J, Hageman I, Jørgensen MB, Jørgensen A. Dynamic regulation of cerebral DNA repair genes by psychological stress. Mutat Res 778:37-43, 2015
- Løhr M, Folkmann JK, Sheykhzade M, Jensen LJ, Kermanizadeh A, Loft S, Møller P. Hepatic oxidative stress, genotoxicity and vascular dysfunction in lean or obese Zucker rats. PLoS One 10:e0118773, 2015
- Klingberg H, Oddershede L, Loeschner K, Larsen EH, Loft S, Møller P. Uptake of gold nanoparticles in primary human endothelial cells. Toxicol Res 4: 655-666, 2015
- Hemmingsen JG, Møller P, Jantzen K, Jönsson BA, Albin M, Wierzbicka A, Gudmundsson A, Loft S, Rissler J. Controlled exposure to diesel exhaust and traffic noise – effects on oxidative stress and activation in mononuclear blood cells. Mutation Res 775:66-71, 2015
- Bekö G, Kjeldsen BU, Olsen Y, Schipperijn J, Wierzbicka A, Karottki DG, Toftum J, Loft S, Clausen G. Contribution of various microenvironments to the daily personal exposure to ultrafine particles: Personal monitoring coupled with GPS tracking. Atmospheric Environ 110: 122-9, 2015
- Hemmingsen JG, Rissler J, Lykkesfeldt J, Sallsten G, Kristiansen J, Møller P, Loft S. Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults. Particle Fibre Toxicol 12: 6, 2015
- Møller P, Yi C, Vesterdal LK, Danielsen PH, Roursgaard M, Klingberg H, Christophersen DV, Loft S. Carbon nanotubes and Cardiovascular Disease, pp 331-41. In Nanotoxicology: Progress Toward Nanomedicine, 2nd Edition. Eds. Monteriro-Riviere, Tran CL. CRC Press, Taylor and Francis Group, 2015
- Klingberg H, Oddershede LB, Loft S, Møller P. Influence of flow, shear stress and adhesion molecule targeting on gold nanoparticle uptake in human endothelial cells. Nanoscale 7: 11409-19, 2015
- Cao Y. Gouveia ACD, Skovmand A, Roursgaard M, Loft S, Møller P. Automobile diesel exhaust particles induce lipid droplet formation in macrophages in vitro. Environmental Toxicol Pharmacol 40: 164-71, 2015
- Bräuner EV, Loft S, Sørensen M, Jensen A, Andersen CE, Ulbak K, Hertel O, Pedersen C, Tjønneland A, Krüger Kjær S, Raaschou-Nielsen O. Residential Radon Exposure and Skin Cancer Incidence in a Prospective Danish Cohort. PLoS One. 2015 Aug 14;10(8):e0135642
- Lacoppidan SA, Kyrø C, Loft S, Helnæs A, Christensen J, Hansen CP, Dahm CC, Overvad K, Tjønneland A, Olsen A. Adherence to a Healthy Nordic Food Index Is Associated with a Lower Risk of Type-2 Diabetes-The Danish Diet, Cancer and Health Cohort Study. Nutrients 7: 8633-44, 2015
- Danielsen PH, Cao Y, Roursgaard M, Møller P, Loft S. Endothelial cell activation, oxidative stress and inflammation induced by a panel of metal-based nanomaterials. Nanotoxicology 9: 813-24, 2015
- Hemmingsen JG, Jantzen K, Møller P, Loft S. No oxidative stress or DNA damage in peripheral blood mononucler cells after exposure to particles from urban street air in overweight elderly. Mutagenesis 30: 635-42, 2015
- Zhang L, Christensen SM, Bendix PM, Bhatia VK, Loft S, Stamou D. Determining the Absolute Diameter of Single Gold Nanoparticles by an Interferometric Optical Approach. Small 11: 3550-5, 2015
- Løhr M, Jensen A, Eriksen L, Grønbæk M. Loft S, Møller P. Association between age and repair of oxidatively damaged DNA in human peripheral blood mononuclear cells. Mutagenesis 30: 695-700, 2015
- Kermanizadeh A, Balharry D, Wallin H, Loft S, Møller P. Nanomaterial translocation - the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs - a review. Crit Rev Toxicol 45: 837-7, 2015
- Bräuner EV, Karottki DG, Frederiksen M, Kolarik B, Spilak M, Andersen ZJ, Vibenholt A, Ellermann T, Gunnarsen L Loft S. Residential Ozone and Lung Function in the Elderly. Indoor Built Environ 25, 93-105, 2016
- Del Bo’C, Cao Y, Roursgaard M, Riso P, Porrini M, Loft S, and Møller P. Anthocyanins and phenolic acids from a wild blueberry (Vaccinium angustifolium) powder counteract lipid accumulation in THP-1 derived macrophages. Eur J Nutr 5: 171-82, 2016
- Cao Y, Roursgaard M, Jacobsen NR, Møller P, Loft S. Monocyte adhesion induced by multi-walled carbon nanotubes and palmitic acid in endothelial cells and alveolar-endothelial co-cultures. Nanotoxicology 10: 235-44, 2016
- Hersoug LG, Møller P, Loft S. Gut microbiota-derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity. Obesity Rev 17: 297-312, 2016
- Kermanizadeh A, Gosens I, Johnston H, Danielsen PH, Jacobsen NR, Lenz AG, Fernandes T, Schins RPF, Cassee FR, Wallin H, Keryling W, SToeger T, Loft S, Møller P, Tran L, Stone V. A multi-laboratory toxicological assessment of a panel of ten engineered nanomaterials to human health - ENPRA project - the good, the bad and the current and future challenges. J Toxicol Environ Health –Part B 19:1, 1-28, 2016
- Møller P, Christophersen DV, Jacobsen NR, Skovmand A, Gouveia ACD, Andersen MHG, Kermanizadeh A, Jensen DM, Danielsen PH, Roursgaard M, Jantzen K, Loft S. Atherosclerosis and vasomotor dysfunction in arteries of animals after exposure to combustion-derived particulate matter or nanomaterials. Crit Rev Toxicol 46: 437-76, 2016
- Hansen AB, Ravnskjær L, Loft S, Andersen KK, Bräuner EB, Baastrup R, Yao C, Ketzel M, Beckerg T, Brandt J, Ole Hertel, Andersen ZJ. Long-term Exposure to Fine Particulate Matter and Incidence of Diabetes in the Danish Nurse Cohort. Environ Int 91:243-250, 2016
- Fisher JE, Loft S, Ulrik CS, Raaschou-Nielsen O, Hertel O, Tjønneland A,Overvad K, Nieuwenhuijsen MJ, Andersen ZJ. Physical Activity, Air Pollution and the Risk of Asthma and Chronic Obstructive Pulmonary Disease. Am J Resp Crit Care Med 194: 855-865, 2016
- Samoli E, Andersen ZJ, Katsouyanni K, Henning F, Kuhlbusch TAJ, Bellander R, Cattani G, Cyrus J, Forastiere F, Jacquemin B, Kulmala M, Lanki T, Loft S, Massling A, Tobias A, Stafoggia M, on behalf of the UF&HEALTH Study group. Exposure to ultrafine particles and respiratory hospitalizations in five European cities. Eur Resp J 48: 674-82, 2016
- Monrad M, Sajadieh A, Christensen JS, Ketzel M, Raaschou-Nielsen O, Tjønneland A, Overvad K, Loft S, Sørensen M. Residential exposure to traffic noise and risk for incident atrial fibrillation: a cohort study. Environ Int 92-93: 457-63, 2016
- Jørgensen JT, Johansen MS, Ravnskjær L, Andersen KK, Bräuner EV, Loft S, Ketzel M, Becker T, Brandt J, Hertel O, Andersen ZJ. Long-term Exposure to Ambient Air Pollution and Incidence of Brain Tumours: The Danish Nurse Cohort. Neurotoxicology 55: 122-30, 2016
- Del Bo C, Roursgaard M, Porrini M, Loft S, Møller P, Riso P. Different effect of anthocyanins and phenolic acids from wild blueberry (Vaccinium angustifolium) on monocytes adhesion to endothelial cells in a TNF-α stimulated pro-inflammatory environment. Mol Nutr Food Res 60: 2355-66, 2016
- Jantzen K, Møller P, Karottki DG, Olsen Y, Bekö G, Clausen G, Hersoug LG, Loft S. Exposure to ultrafine particles, intracellular production of reactive oxygen species in leukocytes and altered levels of endothelial progenitor cells. Toxicology 359-360: 11-18, 2016
- Roursgaard M, Knudsen KB, Northeved H, Persson M, Christensen T, Kumar PE, Permin A, Andresen TL, Gjetting T, Lykkesfeldt J, Vesterdal LK, Loft S, Møller P In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines. Toxicol In Vitro 36: 164-71, 2016
- Christophersen DV, Jacobsen NR, Jensen DM, Kermanizadeh A, Sheykhzade M, Loft S, Vogel U, Wallin H, Møller P. Inflammation and vascular effects after repeated intratracheal instillations of carbon black and lipopolysaccharide. Plos ONE 11: e0160731, 2016
- Christophersen DV, Jacobsen NR, Andersen MHG, Connell SP, Barfod KK, Thomsen MB, Miller MR, Duffin R, Lykkesfeldt J, Vogel U, Wallin H, Loft S, Roursgaard M, Møller P.Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice. Toxicology 371: 29-40, 2016
- Loft S. Reaping the Health Benefits of Tackling Environmental Change. Solutions 7: 21-24, 2016.
- Monrad M, Sajadieh A, Christensen JS, Ketzel M, Raaschou-Nielsen O, Tjønneland A, Overvad K, Loft S, Sørensen M. Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study. Environ Health Perspect 125: 422-427, 2017
- Andersen ZA, Ravnskjær L, Andersen KK, Loft S, Brandt J, Becker T, Ketzel M, Hertel O, Lynge E, Bräuner EV. Long-Term Exposure to Fine Particulate Matter and Breast Cancer Incidence in the Danish Nurse Cohort Study. Cancer Epidemiol Biomarker Prev 26: 428-430, 2017
- Kermanizadeh A, Villadsen K, Østrem RG, Jensen KJ, Møller P, Loft S. Integrin targeting and toxicological assessment of peptide-conjugated liposome delivery systems to activated endothelial cells. Basic Clin Pharmacol Toxicol 120: 380-389, 2017
- Kermanizadeh A, Jantzen K, Ward MB, Durhuus JA, Juel Rasmussen L, Loft S, Møller P. Nanomaterial induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: the role of autophagy and apoptosis. Nanotoxicology 11: 184-200, 2017
- Pedersen M, Andersen Z, Stafoggia M, Weinmayr G, Galassi C, Sørensen M, Eriksen K, Tjønneland A, Loft S, Jaensch A, Nagel G, Concin H, Tsai M-Y, Grioni S, Marcon A, Krogh V, Ricceri F, Sacerdote C, Ranzi A, Sokhi R, Vermeulen R, de Hoogh K, Wang M, Beelen R, Vineis P, Brunekreef B, Hoek G, Raaschou-Nielsen O. Ambient Air Pollution and Primary Liver Cancer Incidence in Four European Cohorts Within the ESCAPE Project..Envir Res 154:226-233, 2017
- Møller KL, Brauer C, Mikkelsen S, Loft S, Simonsen EB, Koblauch H, Bern SH, Alkjær T, Hertel O, Becker T, Larsen KH, Bonde JP. Cohort profile. Copenhagen Airport Cohort – air pollution, manual baggage handling and health. BMJ Open 7:e012651. doi: 10.1136/bmjopen-2016-012651, 2017
- Kermanizadeh A, Jacobsen NR, Roursgaard M, Loft S, Møller P. Hepatic hazard assessment of silver nanoparticle exposure in healthy and chronically alcohol fed mice. Toxicol Sci 158: 176-187, 2017
- Skovmand A, Gouveia AC, Koponen IK, Moller P, Loft S, Roursgaard M. Lung inflammation and genotoxicity in mice lungs after pulmonary exposure to candle light combustion particles. Toxicol Lett 276:31-38, 2017
- Johansson HKL, Hansen JS, Elfving B, Lund SP, Kyjovska ZO, Loft S, Barfod KK, Jackson P, Vogel UB, Hougaard KS. Airway exposure to multi-walled carbon nanotubes disrupts the female reproductive cycle without affecting pregnancy outcomes in mice. Particle Fibre Toxicol 14:17. doi: 10.1186/s12989-017-0197-1, 2017
- Andersen MHG, Saber AT, Pedersen PB, Loft S, Hansen AM, Koponen IK, Pedersen JE, Ebbehoj N, Norskov EC, Clausen PA, Garde AH, Vogel U, Moller P. Cardiovascular health effects following exposure of human volunteers during fire extinction exercises. Environmental Health 16:96. doi: 10.1186/s12940-017-0303-8, 2017
- Kermanizadeh A, Moller P, Loft S, Jacobsen, Dr. Martin Roursgaard. Hepatic toxicity assessment of cationic liposome exposure in healthy and chronic alcohol fed mice. Heliyon 3: e00458, 2017
- Fisher JE, Andersen ZJ, Loft S, Pedersen M. Opportunities and Challenges within Urban Health and Sustainable Development. Curr Opin Envir Sust 25: 77-83, 2017
- Møller P, Jantzen K, Mille Løhr, Andersen MH, Jensen D, Roursgaard M, Danielsen P, Jensen A, Loft S. Searching for assay controls for the Fpg- and hOGG1-modified comet assay. Mutagenesis 33: 9-19, 2018
- Kermanizadeh A, Jantzen K, Brown KM, Møller P, Loft S. A flow cytometry-based method for the screening of nanomaterial-induced reactive oxygen species production in leukocyte sub-populations in whole blood. Basic Clin Pharmacol Toxicol 122: 149-156, 2018
- Jantzen K, Jensen A, Kermanizadeh A, Elholm G, Sigsgaard T, Møller P, Roursgaard M, Loft S. Inhalation of house dust and ozone alters systemic levels of endothelial progenitor cells, oxidative stress and inflammation in elderly subjects. Tox Sci 63: 353-363, 2018
- Andersen MHG, Saber AT, Clausen PA, Pedersen JE, Løhr M, Kermanizadeh A, Loft S, Ebbehoj N, Hansen AM, Pedersen PB, Koponen IK, , Norskov EC, Garde AH, Moller P, Vogel U. Association between polycyclic aromatic hydrocarbons exposure and peripheral blood mononuclear cell DNA damage in human volunteers during fire extinction exercises. Mutagenesis 33: 105-115, 2018
- Møller P, Wallin H, Cassee FR, Loft S. Does intranasal instillation TiO2 cause pulmonary tumorigenesis in male mice? Envir Toxicol 33: 1095-6, 2018
- Hersoug LG, Møller P, Loft S. Role of microbiota-derived lipopolysaccharide in adipose tissue inflammation, adipocyte size, and pyroptosis during obesity. Nutr Res Rev 31: 153-63, 2018
- Jensen DM, Christophersen DV, Sheykhzade M, Skovsted GF, Lykkesfeldt J, Münter R, Roursgaard M, Loft S, Møller P. Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles. Particle Fibre Toxicol 15:12. doi: 10.1186/s12989-018-0248-2.
- Andersena MHG,Saber AT, Pedersenc JE, Pedersen PB, Clausen PA, Løhr M, Kermanizadeh A, Loft S, Ebbehøj N, Hansen AM, Koponen IK, Nørskov EC, Vogel UB, Møller P. Assessment of polycyclic aromatic hydrocarbon exposure, lung function, systemic inflammation, and genotoxicity in peripheral blood mononuclear cells from firefighters before and after a work shift, Environ Mol Mutagen. 59: 539-548, 2018
- Kubesch N, Jørgensen JT, Hoffmann B, Loft S, Nieuwenhuijsen M, Raaschou-Nielsen O, Pedersen M, Hertel O, Overad K, Tjønneland A, Prescott E, Andersen ZJ. Effects of leisure-time and transport-related physical activity on the risk of incident and recurrent myocardial infarction and interaction with traffic-related air pollution: a cohort study. J Am Heart Assoc 7: pii: e009554. doi: 10.1161/JAHA.118.009554, 2018
- Gouveia ACD, Skovmand A, Roursgaard M, Koponen I, Loft S, Jensen A, Møller P. Telomere shortening and aortic plaque progression in Apoliprotein E knockout mice after pulmonary exposure to candle light combustion particles. Mutagenesis 33: 253-261, 2018
- Jensen DM, Skovsted GF, Lykkesfeldt J, Dreier R, Berg JO, Jeppesen JL, Sheykhzade M, Loft S, Møller P Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide. Food Chem Toxicol 120:321-327, 2018
- Brønnum-Hansen H, Bender AM, Andersen ZJ, Sørensen J, Bønløkke JH, Boshuizen H, Becker T, Diderichsen F, Loft S.Assessment of impact of traffic-related air pollution on morbidity and mortality in Copenhagen Municipality and the health gain of reduced exposure. Environ Int 121: 973-980, 2018
- Andersen MHG, Johannesson S, Fonseca A, Clausen P, Saber A, Roursgaard M, Löschner K, Koponen I, Loft S, Vogel U, Moller P. Exposure to air pollution inside electric and diesel-powered passenger trains. Environ Sci Technol 53: 4579-87, 2019
- Jensen DM, Løhr M, Sheykhzade M, Lykkesfeldt J, Wils RS, Loft S, P Møller.Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles. Mutagenesis 34: 203-214, 2019
- Andersen MHG, Frederiksen M, Saber AT, Wills RS, Fonseca AS, Koponen IK, Johannesosson, Roursgaard M, Loft, S, Vogel U, Moller P. Exposure to air pollution inside electric and diesel-powered passenger trains. Health effects of exposure to diesel exhaust in diesel-powered trains. Particle Fibre Toxicol 16: 21, 2019
- Møller P, Jensen A, Løhr M, Eriksen L, Grønbæk M, Loft S. Fish and salad consumption are inversely associated with levels of oxidatively damaged DNA in a Danish adult cohort. Mutation Res 843:66-72. 2019
- Møller KL, Brauer C, Mikkelsen S, Bonde JP, Loft S, Helweg-Larsen K, Thygesen LC. Cardiovascular disease and long-term occupational exposure to ultrafine particles: A cohort study of airport workers. Int J Hyg Environ Health 223: 214-219, 2020
- Holst G, Pørneki AD, Lindgreen J, Thuesen B, Bønløkke J, Hyvärinen A, Elholm G, Østergaard K, Loft S, Brooks C, Douwes J, Linneberg A, Sigsgaard T. Daniel x 1Household dampness and microbial exposure related to allergy and respiratory health in Danish adults. Eur Clin Resp J DOI: 10.1080/20018525.2019.1706235, 2020
- Ma Y, Bellini N, Scholten RH, Andersen MHG, Vogel U, Saber AT, Loft S, Moller P, Roursgaard M. Effect of combustion-derived particles on genotoxicity and telomere length: a study on human cells and exposed populations. Toxicol Lett 322 :20-31, 2020
- Cramer J, Jørgensen JT, Hoffmann B, Loft S, Bräuner EV, Prescott E, Ketzel M, Hertel O, Brandt J, Jensen SS, Backalarz C, Simonsen MK, Andersen ZJ. Long-Term Exposure to Air Pollution and Incidence of Myocardial Infarction: A Danish Nurse Cohort Study. Environ Health Perspect. 2020 May;128(5):57003. doi: 10.1289/EHP5818.
- Amini H, Dehlendorff C, Lim YH, Mehta A, Jørgensen JT, Mortensen LH, Westendorp R, Hoffmann B, Loft S, Bräuner EV, Ketzel M, Hertel O, Brandt J, Jensen SS, Christensen JH, Geels C, Frohn LM, Backalarz C, Simonsen MK, Zorana J. Andersen1 Long-term exposure to air pollution and stroke incidence: A Danish Nurse Cohort study. Environ Int 2020;142:105891. doi: 10.1016/j.envint.2020.105891
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- Christophersen DV, Møller P, Thomsen MB, Lykkesfeldt J, Loft S, Wallin H, Vogel U, Jacobsen NR. Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE-/- mice. FASEB J. 2021 Mar;35(3):e21307. doi: 10.1096/fj.202002017R.
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- Lim Y-H, Jørgensen JT, So R, Cramer J, Amini H, Mehta AJ, Mortensen LH, Westendorp RG, Hoffmann B, Loft S, Bräuner EVm Ketzel M, Hertel O, Brandt J, Jensen SS, Backalarz C, Simonsen MK, Andersen ZJ. Long-term exposure to road traffic noise and incident myocardial infarction: a Danish Nurse Cohort study. Environ Epidemiol 5:e148. doi: 10.1097/EE9.0000000000000148 2021
- Andersen MHG, Loft S, Bønløkke JH, Saber AT, Vogel U, Møller P. Controlled human exposure studies. In Ambient Combustion Ultrafine Particles and Health pp. 205-253. Eds. Brugge D, Fuller CH. Environmental Research Advances. Nova Science Publishers 2021.
- Liu S, Lim YH, Pedersen M, Jørgensen JT, Amini H, Cole-Hunter T, Mehta AJ, So R, Mortensen LH, Westendorp RGJ, Loft S, Bräuner EV, Ketzel M, Hertel O, Brandt J, Jensen SS, Christensen JH, Sigsgaard T, Geels C, Frohn LM, Brborić M, Radonić J, Sekulic MT, Bønnelykke K, Backalarz C, Simonsen MK, Andersen ZJ. Long-term air pollution and road traffic noise exposure and COPD: the Danish Nurse Cohort. Eur Respir J. 2021: 2004594. doi: 10.1183/13993003.04594-2020
- Andersen ZJ, Cramer J, Jørgensen JT, Dehlendorff C, Amini H, Mehta A, Cole-Hunter T, Mortensen LH, Westendorp R, So R, Li S, Hoffmann B, Loft S, Bräuner EV, Ketzel M, Hertel O, Brandt J, Jensen SS, Christensen JH, Geels C, Frohn LM, Backalarz C, Simonsen MK, Lim YH. Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort. Environ Health Perspect. 2021 129: 87002. doi: 10.1289/EHP8090
- Bergmann ML, Andersen ZJ, Amini H, Ellermann T, Hertel O, Lim YH, Loft S, Mehta A, Westendorp RG, Cole-Hunter T. Exposure to ultrafine particles while walking or bicycling during COVID-19 closures: A repeated measures study in Copenhagen, Denmark. Sci Total Environ. 2021 Oct 15;791:148301. doi: 10.1016/j.scitotenv.2021
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- Andersen MGH, Saber AT, Frederiksen M, Clausen PA, Sejbaek CS. Hemmingsen CH, Ebbehøj NE, Catalan J, Aimonen K, Koivisto J, Loft S, Møller P. Vogel U. Occupational exposure and markers of genetic damage, systemic inflammation and lung function: a Danish cross‑sectional study among air force personnel. Sci Rep 11(1):17998. doi: 10.1038/s41598-021-97382-5
- Cole-Hunter T, Dehlendorff C, Amini H, Mehta A, Lim YH, Jørgensen JT, Li S, So R, Mortensen LH, Westendorp R, Hoffmann B, Bräuner EV, Ketzel M, Hertel O, Brandt J, Jensen SS, Christensen JH, Geels C, Frohn LM, Backalarz C, Simonsen MK, Loft S, Andersen ZJ. Long-term exposure to road traffic noise and stroke incidence: a Danish Nurse Cohort study. Environ Health. 2021 Nov 6;20(1):115. doi: 10.1186/s12940-021-00802-2.
- Bergmann ML, Andersen ZJ, Amini H, Khan J, Lim YH, Loft S, Mehta A, Westendorp RG, Cole-Hunter T. Ultrafine particle exposure for bicycle commutes in rush and non-rush hour traffic: A repeated measures study in Copenhagen, Denmark. Environ Pollut. 2021 Dec 3:118631. doi: 10.1016/j.envpol.2021.118631.
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- Petersen KEN, Halkjær J, Loft S, Tjønneland A, Olsen A. Cohort profile and representativeness of participants in the Diet, Cancer and Health-Next Generations cohort study. Eur J Epidemiol. 2022 Jan 4. doi: 10.1007/s10654-021-00832-7
- Lim YH, Hersoug LG, Lund R, Bruunsgaard H, Ketzel M, Brandt J, Jørgensen JT, Westendorp R, Andersen ZJ, Loft S. Inflammatory markers and lung function in relation to indoor and ambient air pollution. Int J Hyg Environ Health. 2022; 241:113944
- Groot J, Keller AC, Pedersen M, Sigsgaard T, Loft S, Andersen AMN. How parental health and socioeconomic characteristics influence housing and indoor home environments of Danish children: a descriptive study. Environ Int 2022; 160:107059
- So R, Andersen ZJ, Chen J, Stafoggia M, de Hoogh K, Katsouyanni K, Vienneau D, Rodopoulou S, Samoli E, Lim YH, Jørgensen JT, Amini H, Cole-Hunter T, Mahmood Taghavi Shahri S, Maric M, Bergmann M, Liu S, Azam S, Loft S, Westendorp RGJ, Mortensen LH, Bauwelinck M, Klompmaker JO, Atkinson R, Janssen NAH, Oftedal B, Renzi M, Forastiere F, Strak M, Thygesen LC, Brunekreef B, Hoek G, Mehta AJ. Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: Beyond mortality from cardiopulmonary disease and lung cancer.Environ Int. 2022 Apr 12;164:107241. doi: 10.1016/j.envint.2022.107241