Publikationer pr. år
Publikationer pr. år
Personlig profil
Kort præsentation
The Rasmussen Group explores the interaction between the hallmarks of aging: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication.
CV
Yuan Li
E-mail: [email protected]
Language skills: Chinese, English, Danish
Relevant Work Experiences
2019- University of Copenhagen- Center for Healthy Aging-Department of Cellular and Molecular Medicine
- Postdoctoral Fellow at Laboratory of Prof. Lene Juel Rasmussen
- Project: The Study of Mitochondrial and Mitophagy in the
Pathophysiology of Alzheimer’s Disease
2016-2018 University of Copenhagen-Department of Gastroenterology, Herlev Hospital
- Postdoctoral Fellow at Laboratory of Prof. Ole Haagen Nielsen
- Project: COX-2-PGE2 Signaling Impairs Intestinal Epithelial
Regeneration and Associates with TNF Inhibitor Responsiveness in
Ulcerative Colitis.
2014-2015 University of Michigan-Department of Cardiac Surgery
- Postdoctoral Fellow-Laboratory of Prof. Y. Eugene Chen
- Project: Studying Lipid Metabolism Using Human iPSC-derived
Hepatocyte-like Cells
2013-2014 Chinese Academy of Sciences-Guangzhou Institutes of Biomedicine and Health Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative
Medicine, South China Institute for Stem Cell Biology and Regenerative
Medicine
- Research Assistant-Laboratory of Dr. Duanqing Pei
- Project: Role of Autophagy and mTORC1 in Somatic Cell Reprogramming
Education
2008-2013 University of Science and Technology of China-School of Life Sciences
and Key Laboratory of Regenerative Biology of the Chinese Academy of
Sciences and Guangdong Provincial Key Laboratory of Stem Cells and
Regenerative Medicine, South China Institute for Stem Cell Biology and
Regenerative Medicine
- Ph.D. in Biochemistry and Molecular Biology-Laboratory of Dr.
Duanqing pei - Project: Role of Autophagy and mTORC1 in Somatic Cell
Reprogramming
2004-2008 Sichuan Agriculture University-School of Animal Sciences
- B.S. in Bioengineering
Grant
- Aase og Ejnar Danielsens Foundation F-19215-00-27, 2017
- A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal, 2018
IT skills
- Adobe AI and Microsoft Office – Professional user
- GraphPad Prism-Professional user
Samarbejde og topforskningsområder i de sidste fem år
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FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species
Song, J., Li, Z., Zhou, L., Chen, X., Sew, W. Q. G., Herranz, H., Ye, Z., Olsen, J. V., Li, Y., Nygaard, M., Christensen, K., Tong, X., Bohr, V. A., Rasmussen, L. J. & Dai, F., 2024, I: Nature Communications. 15, 1, 18 s., 7144.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Human fibroblasts from sporadic Alzheimer's disease (AD) patients show mitochondrial alterations and lysosome dysfunction
Li, Y., Li, Z., Grillo, E., Desler, C., Navarro, C., Bohr, V. A., Berliocchi, L. & Rasmussen, L. J., 2024, I: Free Radical Biology and Medicine. 222, s. 569-578 10 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Interactions between mitochondrial dysfunction and other hallmarks of aging: Paving a path toward interventions that promote healthy old age
Li, Y., Berliocchi, L., Li, Z. & Rasmussen, L. J., 2024, I: Aging Cell. 23, 1, 12 s., e13942.Publikation: Bidrag til tidsskrift › Review › Forskning › peer review
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Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Y., Orduña Dolado, A., Li, Z., Andersson, R., Berliocchi, L. & Rasmussen, L. J., 2023, I: Frontiers in Aging Neuroscience. 15, 14 s., 1101216.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, S., Li, Z., Li, Y., Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, V. A., Desler, C., Naviaux, R. K. & Rasmussen, L. J., 2023, I: Heliyon. 9, 6, e17392.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout
Giguère, N., Delignat-Lavaud, B., Herborg, F., Voisin, A., Li, Y., Jacquemet, V., Anand-Srivastava, M., Gether, U., Giros, B. & Trudeau, L-E., 2019, I: PLOS Genetics. 15, 8, 26 s., e1008352.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 flere, , 2018, I: Nature Communications. 9, 19 s., 1661.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Y., Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, L. B., Seidelin, J. B., Jensen, K. B. & Nielsen, O. H., 2018, I: EBioMedicine. 36, s. 497-507Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil61 Citationer (Scopus)151 Downloads (Pure)