Publikationer pr. år
Publikationer pr. år
Personlig profil
Aktuel forskning
Signals or cues from the environment, diet, circadian clock, and other organs exert substantial control over the plasticity and function of adipose tissue. The overarching goal of my group is to uncover how these diverse 'inputs' converge on adipocytes to uniquely shape adipose tissue biology and coordinate organismal energy metabolism. Specifically, we focus on identifying cell surface receptors, intracellular enzymes, and transporters that represent key regulatory nodes in influencing adipose tissue catabolism. By combining global gene, protein, metabolite, and lipid profiling with cutting-edge in vivo physiological phenotyping and pharmacological engineering, we believe we are ideally poised to make transformative breakthroughs in the basic understanding of adipose biology and to develop innovative strategies for counteracting metabolic disease.
Mulige interessekonflikter
I am a co-founder of Embark Biotech ApS, a company developing therapeutics for the treatment of type 2 diabetes and obesity.
Uddannelse (Akademiske kvalifikationer)
Biochemistry-Cellular and Molecular Biology, Ph.D., Johns Hopkins University
Dimissionsdato: 1 mar. 2011
Emneord
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MCT1 helps brown fat suck up succinate
Lund, J., Isidor, M. S. & Gerhart-Hines, Z., 2024, I: Nature Metabolism. 6, s. 387–388Publikation: Bidrag til tidsskrift › Letter › Forskning › peer review
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Mild Cold Stress at Ambient Temperature Elevates Muscle Calcium Cycling and Exercise Adaptations in Obese Female Mice
Raun, S. H., Braun, J. L., Karavaeva, I., Henriquez-Olguín, C., Ali, M. S., Møller, L. L. V., Gerhart-Hines, Z., Fajardo, V. A., Richter, E. A. & Sylow, L., 2024, I: Endocrinology (United States). 165, 10, bqae102.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia, C. M., Præstholm, S. M., Havelund, J. F., Pedersen, F. B., Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Z., Heeren, J., Brewer, J., Larsen, S., Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, I: Endocrinology. 164, 10, s. 1-17 164.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
2 Citationer (Scopus) -
Editorial overview: Fat tissue in focus: Assembled deeply insightful perspectives on state-of-the-art explorations
Gerhart-Hines, Z. & Loos, R., 2023, I: Current Opinion in Genetics and Development. 83, 102117.Publikation: Bidrag til tidsskrift › Leder › Forskning
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Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue
Bager Christensen, I., Blom, I., Dohlmann, T. L., Finger, F., W Helge, J., Gerhart-Hines, Z., Dela, F. & Larsen, S., 2023, I: Journal of Clinical Endocrinology and Metabolism. 108, 10, s. e916-e922 7 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Full activation of thermogenesis in brown adipocytes requires Basigin action
Rupar, K., Isidor, M. S., Argemi-Muntadas, L., Agueda-Oyarzabal, M., Plucińska, K., Brown, E. L., Mattanovich, M., Bossi, S., Tozzi, M., Tandio, D., Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, J. B., Gerhart-Hines, Z., Nielsen, S., Moritz, T. & Emanuelli, B., 2023, I: F E B S Journal. 290, 10, s. 2673-2691Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil2 Citationer (Scopus)94 Downloads (Pure) -
Is lactate a driver of skin burn-induced adipose browning?
Lund, J., Johansen, V. B. I., Clemmensen, C. & Gerhart-Hines, Z., 2023, I: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, s. E421-E422 2 s.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning
1 Citationer (Scopus) -
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Z. & Funai, K., 2023, I: Science Advances. 9, 8, 15 s., eade7864.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil21 Citationer (Scopus)27 Downloads (Pure)