Abstract
Increased left ventricular mass (LVM) is a strong independent predictor for adverse cardiovascular events, but conventional echocardiographic methods are limited by poor reproducibility and accuracy. We developed a novel method based on adding the mean wall thickness from the parasternal short axis view, to the left ventricular end-diastolic volume acquired using the biplane model of discs. The participants (n = 85) had various left ventricular geometries and were assessed using echocardiography followed immediately by cardiac magnetic resonance, as reference. We compared our novel two-dimensional (2D) method to various conventional one-dimensional (1D) and other 2D methods as well as the three-dimensional (3D) method. Our novel method had better reproducibility in intra-examiner [coefficients of variation (CV) 9% vs. 11–14%] and inter-examiner analysis (CV 9% vs. 10–20%). Accuracy was similar to the 3D method (mean difference ± 95% limits of agreement, CV): Novel: 2 ± 50 g, 15% vs. 3D: 2 ± 51 g, 16%; and better than the “linear” 1D method by Devereux (7 ± 76 g, 23%). Our novel method is simple, has considerable better reproducibility and accuracy than conventional “linear” 1D methods, and similar accuracy as the 3D-method. As the biplane model forms part of the standard echocardiographic protocol, it does not require specific training and provides a supplement to the modern echocardiographic report.
Originalsprog | Engelsk |
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Artikelnummer | 9980 |
Tidsskrift | Scientific Reports |
Vol/bind | 12 |
ISSN | 2045-2322 |
DOI | |
Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:We would like to thank radiograph and CMR-technologist Jesper Kromann (Department of Diagnostic Radiology, Rigshospitalet, Denmark) for technical support. This work was funded by the Augustinus Foundation (Application Number 16-3012) and by the research fund of The Heart Center at Rigshospitalet, Denmark.
Funding Information:
We would like to thank radiograph and CMR-technologist Jesper Kromann (Department of Diagnostic Radiology, Rigshospitalet, Denmark) for technical support. This work was funded by the Augustinus Foundation (Application Number 16-3012) and by the research fund of The Heart Center at Rigshospitalet, Denmark.
Publisher Copyright:
© 2022, The Author(s).