A novel proteomic biomarker panel as a diagnostic tool for patients with ovarian cancer

Claus Høgdall, Eric T Fung, Ib J Christensen, Lotte Nedergaard, Svend A Engelholm, Anette L Petri, Signe Risum, Lene Lundvall, Christine Yip, Anette T Pedersen, Dorthe Hartwell, Lee Lomas, Estrid V S Høgdall

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    Abstract

    Previous reports have shown that the proteomic markers apolipoprotein A1, hepcidin, transferrin, inter-alpha trypsin IV internal fragment, transthyretin, connective-tissue activating protein 3 and beta-2 microglobulin may discriminate between a benign pelvic mass and ovarian cancer (OC). The aim was to determine if these serum proteomic biomarkers alone as well as in combination with age and serum CA125, could be helpful in triage of women with a pelvic mass.
    OriginalsprogEngelsk
    TidsskriftGynecologic Oncology
    Vol/bind123
    Udgave nummer2
    Sider (fra-til)308-13
    Antal sider6
    ISSN0090-8258
    DOI
    StatusUdgivet - 2011

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