A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer

C Qvortrup; Benny Vittrup Jensen; T Fokstuen; Svend Erik Nielsen; N Keldsen; B Glimelius; B Bjerregaard; J Mejer; F O Larsen; Per Pfeiffer

doi:10.1093/annonc/mdp272

A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer

C Qvortrup, Benny Vittrup Jensen, T Fokstuen, Svend Erik Nielsen, N Keldsen, B Glimelius, B Bjerregaard, J Mejer, F O Larsen, Per Pfeiffer

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

32 Citationer (Scopus)

Abstract

Chronotherapy is one of the several approaches to increase efficacy and reduce toxicity of chemotherapy. In a phase II study in the second-line in patients with metastatic colorectal cancer (mCRC), we found that chronomodulated XELOX (XELOX(30Chron)) was a well-tolerated regimen with potentially reduced toxicity.

Originalsprog	Engelsk
Tidsskrift	Annals of Oncology
Vol/bind	21
Udgave nummer	1
Sider (fra-til)	87-91
Antal sider	5
ISSN	0923-7534
DOI	https://doi.org/10.1093/annonc/mdp272
Status	Udgivet - 1 jan. 2010

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10.1093/annonc/mdp272

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Citationsformater

Qvortrup, C., Jensen, B. V., Fokstuen, T., Nielsen, S. E., Keldsen, N., Glimelius, B., Bjerregaard, B., Mejer, J., Larsen, F. O., & Pfeiffer, P. (2010). A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer. Annals of Oncology, 21(1), 87-91. https://doi.org/10.1093/annonc/mdp272

A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer. / Qvortrup, C; Jensen, Benny Vittrup; Fokstuen, T et al.
I: Annals of Oncology, Bind 21, Nr. 1, 01.01.2010, s. 87-91.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Qvortrup, C, Jensen, BV, Fokstuen, T, Nielsen, SE, Keldsen, N, Glimelius, B, Bjerregaard, B, Mejer, J, Larsen, FO & Pfeiffer, P 2010, 'A randomized study comparing short-time infusion of oxaliplatin in combination with capecitabine XELOX(30) and chronomodulated XELOX(30) as first-line therapy in patients with advanced colorectal cancer', Annals of Oncology, bind 21, nr. 1, s. 87-91. https://doi.org/10.1093/annonc/mdp272

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abstract = "Chronotherapy is one of the several approaches to increase efficacy and reduce toxicity of chemotherapy. In a phase II study in the second-line in patients with metastatic colorectal cancer (mCRC), we found that chronomodulated XELOX (XELOX(30Chron)) was a well-tolerated regimen with potentially reduced toxicity.",

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