Abatacept til behandling af reumatoid artritis

Henrik Nielsen; Annette Hansen

Abatacept til behandling af reumatoid artritis

Henrik Nielsen, Annette Hansen

Institut for Klinisk Medicin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the naïve T cells and interfering with a central inflammatory rheumatoid arthritis signal pathway.
Udgivelsesdato: 2009-Jan

Bidragets oversatte titel	Abatacept in the treatment of active rheumatoid arthritis
Originalsprog	Dansk
Tidsskrift	Ugeskrift for læger
Vol/bind	171
Udgave nummer	4
Sider (fra-til)	214-7
Antal sider	4
ISSN	0041-5782
Status	Udgivet - 2009

Bibliografisk note

Keywords: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunoconjugates; Immunosuppressive Agents; Treatment Outcome

Citationsformater

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abstract = "Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the na{\"i}ve T cells and interfering with a central inflammatory rheumatoid arthritis signal pathway. Udgivelsesdato: 2009-Jan",

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AU - Hansen, Annette

N1 - Keywords: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunoconjugates; Immunosuppressive Agents; Treatment Outcome

PY - 2009

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AB - Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the naïve T cells and interfering with a central inflammatory rheumatoid arthritis signal pathway. Udgivelsesdato: 2009-Jan

M3 - Tidsskriftartikel

C2 - 19174034

SN - 0041-5782

VL - 171

SP - 214

EP - 217

JO - Ugeskrift for læger

JF - Ugeskrift for læger

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