TY - JOUR
T1 - Adenosquamous carcinoma of the larynx associated with necrotizing sialometaplasia--a diagnostic challenge
AU - Ravn, Tomaas
AU - Trolle, Waldemar
AU - Kiss, Katalin
AU - Balle, Viggo Hulthin
N1 - Keywords: Adult; Biopsy; Carcinoma, Adenosquamous; Comorbidity; Diagnosis, Differential; Epiglottis; Female; Humans; Hypopharynx; Laryngeal Diseases; Laryngeal Neoplasms; Laryngoscopy; Magnetic Resonance Imaging; Neoplasm Invasiveness; Sialometaplasia, Necrotizing; Vocal Cords
PY - 2009
Y1 - 2009
N2 - Necrotizing sialometaplasia is a benign, self-limiting, inflammatory process involving salivary glands, commonly associated with tissue ischemia. Clinically, necrotizing sialometaplasia is most often found in the hard palate as a deep ulcer with raised, indurated edges that can be indolent. This, as well as the histopathologic findings of necrotizing sialometaplasia, can be confused with those of a malignant neoplasm. We report a rare case of necrotizing sialometaplasia in the larynx, probably initiated by an underlying malignant process. We suggest an aggressive diagnostic approach, when necrotizing sialometaplasia involves the larynx and no recent exposure to radiation, surgery or trauma has been recorded. Necrotizing sialometaplasia of the larynx should be regarded as secondary to malignancy until proven otherwise.
AB - Necrotizing sialometaplasia is a benign, self-limiting, inflammatory process involving salivary glands, commonly associated with tissue ischemia. Clinically, necrotizing sialometaplasia is most often found in the hard palate as a deep ulcer with raised, indurated edges that can be indolent. This, as well as the histopathologic findings of necrotizing sialometaplasia, can be confused with those of a malignant neoplasm. We report a rare case of necrotizing sialometaplasia in the larynx, probably initiated by an underlying malignant process. We suggest an aggressive diagnostic approach, when necrotizing sialometaplasia involves the larynx and no recent exposure to radiation, surgery or trauma has been recorded. Necrotizing sialometaplasia of the larynx should be regarded as secondary to malignancy until proven otherwise.
U2 - 10.1016/j.anl.2009.04.008
DO - 10.1016/j.anl.2009.04.008
M3 - Journal article
C2 - 19482450
SN - 0385-8146
VL - 36
SP - 721
EP - 724
JO - Auris Nasus Larynx
JF - Auris Nasus Larynx
IS - 6
ER -