ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study.

Vieri Grandi; Stefano Bacci; Alessandro Corsi; Maurizio Sessa; Elisa Puliti; Nicoletta Murciano; Francesca Scavone; Pietro Cappugi; Nicola Pimpinelli

doi:10.1016/j.pdpdt.2017.12.012

ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study.

Vieri Grandi, Stefano Bacci, Alessandro Corsi, Maurizio Sessa, Elisa Puliti, Nicoletta Murciano, Francesca Scavone, Pietro Cappugi, Nicola Pimpinelli

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

31 Citationer (Scopus)

Abstract

A cohort of 19 patients affected by chronic venous ulcers was recruited from our centre. A 4-mm punch biopsy from wound bed was taken before application of ALA 20% gel and repeated one hour after the first PDT irradiation. We observed a significant and progressive reduction of wounds mean volumes right after three ALA-PDT sessions (once per week; 4479.9+/-345.5mm(3) vs 34599+/-190.3mm(3), p

Originalsprog	Engelsk
Tidsskrift	Photodiagnosis and Photodynamic Therapy
Vol/bind	21
Sider (fra-til)	252-256
Antal sider	5
ISSN	1572-1000
DOI	https://doi.org/10.1016/j.pdpdt.2017.12.012
Status	Udgivet - mar. 2018
Udgivet eksternt	Ja

Adgang til dokumentet

10.1016/j.pdpdt.2017.12.012

Citationsformater

Grandi, V., Bacci, S., Corsi, A., Sessa, M., Puliti, E., Murciano, N., Scavone, F., Cappugi, P., & Pimpinelli, N. (2018). ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study. Photodiagnosis and Photodynamic Therapy, 21, 252-256. https://doi.org/10.1016/j.pdpdt.2017.12.012

ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study. / Grandi, Vieri; Bacci, Stefano; Corsi, Alessandro et al.
I: Photodiagnosis and Photodynamic Therapy, Bind 21, 03.2018, s. 252-256.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Grandi, V, Bacci, S, Corsi, A, Sessa, M, Puliti, E, Murciano, N, Scavone, F, Cappugi, P & Pimpinelli, N 2018, 'ALA-PDT exerts beneficial effects on chronic venous ulcers by inducing changes in inflammatory microenvironment, especially through increased TGF-beta release: A pilot clinical and translational study.', Photodiagnosis and Photodynamic Therapy, bind 21, s. 252-256. https://doi.org/10.1016/j.pdpdt.2017.12.012

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abstract = "A cohort of 19 patients affected by chronic venous ulcers was recruited from our centre. A 4-mm punch biopsy from wound bed was taken before application of ALA 20% gel and repeated one hour after the first PDT irradiation. We observed a significant and progressive reduction of wounds mean volumes right after three ALA-PDT sessions (once per week; 4479.9+/-345.5mm(3) vs 34599+/-190.3mm(3), p",

author = "Vieri Grandi and Stefano Bacci and Alessandro Corsi and Maurizio Sessa and Elisa Puliti and Nicoletta Murciano and Francesca Scavone and Pietro Cappugi and Nicola Pimpinelli",

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AU - Grandi, Vieri

AU - Bacci, Stefano

AU - Corsi, Alessandro

AU - Sessa, Maurizio

AU - Puliti, Elisa

AU - Murciano, Nicoletta

AU - Scavone, Francesca

AU - Cappugi, Pietro

AU - Pimpinelli, Nicola

PY - 2018/3

Y1 - 2018/3

N2 - A cohort of 19 patients affected by chronic venous ulcers was recruited from our centre. A 4-mm punch biopsy from wound bed was taken before application of ALA 20% gel and repeated one hour after the first PDT irradiation. We observed a significant and progressive reduction of wounds mean volumes right after three ALA-PDT sessions (once per week; 4479.9+/-345.5mm(3) vs 34599+/-190.3mm(3), p

AB - A cohort of 19 patients affected by chronic venous ulcers was recruited from our centre. A 4-mm punch biopsy from wound bed was taken before application of ALA 20% gel and repeated one hour after the first PDT irradiation. We observed a significant and progressive reduction of wounds mean volumes right after three ALA-PDT sessions (once per week; 4479.9+/-345.5mm(3) vs 34599+/-190.3mm(3), p

U2 - 10.1016/j.pdpdt.2017.12.012

DO - 10.1016/j.pdpdt.2017.12.012

M3 - Journal article

C2 - 29277361

SN - 1572-1000

VL - 21

SP - 252

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JO - Photodiagnosis and Photodynamic Therapy

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