AMPK: A key sensor of fuel and energy status in skeletal muscle

D. Grahame Hardie; Kei Sakamoto

doi:10.1152/physiol.00044.2005

AMPK: A key sensor of fuel and energy status in skeletal muscle

D. Grahame Hardie^*, Kei Sakamoto

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Review › peer review

458 Citationer (Scopus)

Abstract

Contraction induces marked metabolic changes in muscle, and the AMP-activated protein kinase (AMPK) is a good candidate to explain these effects. Recent work using a muscle-specific knockout of the upstream kinase, LKB1, has confirmed that the LKB1→AMPK cascade is the signaling pathway responsible for many of these effects.

Originalsprog	Engelsk
Tidsskrift	Physiology
Vol/bind	21
Udgave nummer	1
Sider (fra-til)	48-60
Antal sider	13
ISSN	1548-9213
DOI	https://doi.org/10.1152/physiol.00044.2005
Status	Udgivet - 1 feb. 2006
Udgivet eksternt	Ja

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10.1152/physiol.00044.2005

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Citationsformater

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