An online GPCR structure analysis platform

Albert J. Kooistra*, Christian Munk, Alexander S. Hauser, David E. Gloriam*

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

16 Citationer (Scopus)
57 Downloads (Pure)

Abstract

We present an online, interactive platform for comparative analysis of all available G-protein coupled receptor (GPCR) structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue–residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied receptor research studies.

OriginalsprogEngelsk
TidsskriftNature Structural and Molecular Biology
Vol/bind28
Udgave nummer11
Sider (fra-til)875-878
ISSN1545-9993
DOI
StatusUdgivet - 2021

Bibliografisk note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature America, Inc.

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