Abstract
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Nephrology, Dialysis, Transplantation |
| Vol/bind | 24 |
| Udgave nummer | 12 |
| Sider (fra-til) | 3557-66 |
| Antal sider | 10 |
| ISSN | 0931-0509 |
| DOI | |
| Status | Udgivet - 2009 |
Bibliografisk note
Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Europe; Female; Humans; Infant; Kidney Failure, Chronic; Male; Middle Aged; Registries; Renal Replacement Therapy; Time Factors; Young AdultAdgang til dokumentet
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An update on renal replacement therapy in Europe: ERA-EDTA Registry data from 1997 to 2006. / Kramer, Anneke; Stel, Vianda; Zoccali, Carmine; Heaf, James; Ansell, David; Grönhagen-Riska, Carola; Leivestad, Torbjørn; Simpson, Keith; Pálsson, Runólfur; Postorino, Maurizio; Jager, Kitty; ERA-EDTA Registry.
I: Nephrology, Dialysis, Transplantation, Bind 24, Nr. 12, 2009, s. 3557-66.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - An update on renal replacement therapy in Europe: ERA-EDTA Registry data from 1997 to 2006
AU - Kramer, Anneke
AU - Stel, Vianda
AU - Zoccali, Carmine
AU - Heaf, James
AU - Ansell, David
AU - Grönhagen-Riska, Carola
AU - Leivestad, Torbjørn
AU - Simpson, Keith
AU - Pálsson, Runólfur
AU - Postorino, Maurizio
AU - Jager, Kitty
AU - ERA-EDTA Registry
N1 - Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Europe; Female; Humans; Infant; Kidney Failure, Chronic; Male; Middle Aged; Registries; Renal Replacement Therapy; Time Factors; Young Adult
PY - 2009
Y1 - 2009
N2 - BACKGROUND: Recent studies have indicated a stabilization in the incidence rates of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in a number of European countries. The aim of this study was to provide an update on the incidence, prevalence and outcomes of RRT in Europe over the past decade. METHODS: Nineteen European national or regional renal registries with registry data from 1997 to 2006 participated in the study. Incidence and prevalence trends were analysed with Poisson and Joinpoint regression. Cox regression methods were used to examine patient survival. RESULTS: The total adjusted incidence rate of RRT for ESRD increased from 109.9 per million population (pmp) in 1997 to 119.7 pmp in 2000, i.e. an average annual percentage change (AAPC) of 2.9% (95% CI 2.1-3.8%). Thereafter, the incidence increased at a much lower rate to 125.4 pmp in 2006 [AAPC 0.6% (95% CI 0.3-0.8%)]. This change in the trend of the incidence of RRT was largely due to a stabilization in the incidence rates of RRT for females aged 65-74 years, males aged 75-84 years and patients receiving RRT for ESRD due to hypertension/renal vascular disease. The overall adjusted prevalence in Europe continued to increase linearly at 2.7% per year. Between the periods 1997-2001 and 2002-2006, the risk of death decreased for all treatment modalities, with the most substantial improvement in patients starting peritoneal dialysis [19% (95% CI 15-22%)] and in patients receiving a kidney transplant [17% (95% CI 11-23%)]. CONCLUSION: This European study shows that the annual rise of the overall incidence rate of RRT for ESRD has diminished and that in several age groups the incidence rates have now stabilized. The survival of dialysis patients and kidney transplant recipients has continued to improve.
AB - BACKGROUND: Recent studies have indicated a stabilization in the incidence rates of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in a number of European countries. The aim of this study was to provide an update on the incidence, prevalence and outcomes of RRT in Europe over the past decade. METHODS: Nineteen European national or regional renal registries with registry data from 1997 to 2006 participated in the study. Incidence and prevalence trends were analysed with Poisson and Joinpoint regression. Cox regression methods were used to examine patient survival. RESULTS: The total adjusted incidence rate of RRT for ESRD increased from 109.9 per million population (pmp) in 1997 to 119.7 pmp in 2000, i.e. an average annual percentage change (AAPC) of 2.9% (95% CI 2.1-3.8%). Thereafter, the incidence increased at a much lower rate to 125.4 pmp in 2006 [AAPC 0.6% (95% CI 0.3-0.8%)]. This change in the trend of the incidence of RRT was largely due to a stabilization in the incidence rates of RRT for females aged 65-74 years, males aged 75-84 years and patients receiving RRT for ESRD due to hypertension/renal vascular disease. The overall adjusted prevalence in Europe continued to increase linearly at 2.7% per year. Between the periods 1997-2001 and 2002-2006, the risk of death decreased for all treatment modalities, with the most substantial improvement in patients starting peritoneal dialysis [19% (95% CI 15-22%)] and in patients receiving a kidney transplant [17% (95% CI 11-23%)]. CONCLUSION: This European study shows that the annual rise of the overall incidence rate of RRT for ESRD has diminished and that in several age groups the incidence rates have now stabilized. The survival of dialysis patients and kidney transplant recipients has continued to improve.
U2 - 10.1093/ndt/gfp519
DO - 10.1093/ndt/gfp519
M3 - Journal article
C2 - 19820003
VL - 24
SP - 3557
EP - 3566
JO - Nephrology, Dialysis, Transplantation
JF - Nephrology, Dialysis, Transplantation
SN - 0931-0509
IS - 12
ER -