TY - JOUR
T1 - Analgesic Overdose in Patients With Dental Pain. A Cross-Sectional Study in Two Dental Emergency Clinics
AU - Larsen, Sofie Krahl
AU - Markvart, Merete
AU - Søndenbroe, Rasmus
AU - Dalhoff, Kim
AU - Jensen, Simon Storgård
N1 - © 2025 The Author(s). Basic & Clinical Pharmacology & Toxicology published by John Wiley & Sons Ltd on behalf of Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society).
PY - 2025
Y1 - 2025
N2 - Dental pain is common, and many patients use analgesics to alleviate the pain. Analgesics are readily accessible, and overdosing may lead to severe complications. This study explores the extent of analgesic overdosing in patients with dental pain. Data were collected from two dental emergency clinics in Copenhagen, Denmark, via questionnaires and interviews with 180 patients. Results showed that 82.8% (n = 149) had taken at least one type of analgesic, and 9% (n = 15) had exceeded the recommended maximum dosage. Of all patients with dental pain, 75.6% (n = 136) used paracetamol, 54.4% (n = 98) ibuprofen, 10% (n = 18) opioids, and 11.1% (n = 20) other types of analgesics. Most frequently, the pain was of pulpal origin (n = 119; 66.1%). Of all analgesics used, most were obtained places where guidance should be available, for example, pharmacies, dental clinics or hospitals (n = 152; 54%). The patients were aware of the recommended maximum daily dosage for paracetamol and ibuprofen in 39% (n = 70) and 41% (n = 73) of the cases, respectively. In conclusion, most patients with dental pain use analgesics to alleviate their pain. A substantial proportion of these patients overdose themselves, potentially putting them at risk of severe systemic complications. This study highlights the need for better patient education and safer pain management strategies.
AB - Dental pain is common, and many patients use analgesics to alleviate the pain. Analgesics are readily accessible, and overdosing may lead to severe complications. This study explores the extent of analgesic overdosing in patients with dental pain. Data were collected from two dental emergency clinics in Copenhagen, Denmark, via questionnaires and interviews with 180 patients. Results showed that 82.8% (n = 149) had taken at least one type of analgesic, and 9% (n = 15) had exceeded the recommended maximum dosage. Of all patients with dental pain, 75.6% (n = 136) used paracetamol, 54.4% (n = 98) ibuprofen, 10% (n = 18) opioids, and 11.1% (n = 20) other types of analgesics. Most frequently, the pain was of pulpal origin (n = 119; 66.1%). Of all analgesics used, most were obtained places where guidance should be available, for example, pharmacies, dental clinics or hospitals (n = 152; 54%). The patients were aware of the recommended maximum daily dosage for paracetamol and ibuprofen in 39% (n = 70) and 41% (n = 73) of the cases, respectively. In conclusion, most patients with dental pain use analgesics to alleviate their pain. A substantial proportion of these patients overdose themselves, potentially putting them at risk of severe systemic complications. This study highlights the need for better patient education and safer pain management strategies.
KW - Humans
KW - Female
KW - Male
KW - Cross-Sectional Studies
KW - Adult
KW - Drug Overdose
KW - Middle Aged
KW - Acetaminophen/poisoning
KW - Ibuprofen/adverse effects
KW - Denmark/epidemiology
KW - Young Adult
KW - Surveys and Questionnaires
KW - Analgesics/administration & dosage
KW - Aged
KW - Toothache/drug therapy
KW - Analgesics, Opioid/adverse effects
KW - Dental Clinics
KW - Adolescent
KW - Analgesics, Non-Narcotic/poisoning
U2 - 10.1111/bcpt.14124
DO - 10.1111/bcpt.14124
M3 - Journal article
C2 - 39825523
SN - 1742-7835
VL - 136
JO - Basic & clinical pharmacology & toxicology
JF - Basic & clinical pharmacology & toxicology
IS - 2
M1 - e14124
ER -