@inbook{54205f31dbee4b0cb319c571ddf20c1c,
title = "Analysis of antibody inhibition of PfEMP1 binding by competition ELISA",
abstract = "Plasmodium falciparum express variant antigens on the surface of infected erythrocytes (IEs). These include proteins of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family. PfEMP1 proteins mediate binding of IEs to various human endothelial receptors and induce antibodies response during natural infections. In this chapter, we describe a competition ELISA that is an assay for antibodies neutralizing binding of PfEMP1 proteins to their cognate receptor.",
keywords = "Antibodies, Protozoan, Antigens, Protozoan, Enzyme-Linked Immunosorbent Assay, Erythrocytes/metabolism, Humans, Malaria, Falciparum, Plasmodium falciparum/metabolism, Protein Binding, Protozoan Proteins/metabolism",
author = "Olsen, {Rebecca W} and Jennifer Suurbaar and Jensen, {Anja Ramstedt}",
note = "{\textcopyright} 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2022",
doi = "10.1007/978-1-0716-2189-9_36",
language = "English",
volume = "2470",
series = "Methods in molecular biology (Clifton, N.J.)",
publisher = "Humana Press",
pages = "485--491",
booktitle = "Malaria Immunology",
address = "United States",
}