Abstract
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Transboundary and Emerging Diseases |
| Vol/bind | 57 |
| Udgave nummer | 4 |
| Sider (fra-til) | 286-92 |
| Antal sider | 6 |
| ISSN | 1865-1674 |
| DOI | |
| Status | Udgivet - 2010 |
Bibliografisk note
Keywords:foot-and-mouth disease;serotypes;seroprevalence;African buffalosAdgang til dokumentet
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I: Transboundary and Emerging Diseases, Bind 57, Nr. 4, 2010, s. 286-92.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - Antibodies against foot-and-mouth disease (FMD) virus in African buffalos (Syncerus caffer) in selected National Parks in Uganda (2001-2003)
AU - Ayebazibwe, C
AU - Mwiine, F N
AU - Balinda, S N
AU - Tjørnehøj, K
AU - Masembe, C
AU - Muwanika, V B
AU - Okurut, A R A
AU - Siegismund, H R
AU - Alexandersen, S
N1 - Keywords:foot-and-mouth disease;serotypes;seroprevalence;African buffalos
PY - 2010
Y1 - 2010
N2 - In East Africa, the foot-and-mouth disease (FMD) virus (FMDV) isolates have over time included serotypes O, A, C, Southern African Territories (SAT) 1 and SAT 2, mainly from livestock. SAT 3 has only been isolated in a few cases and only in African buffalos (Syncerus caffer). To investigate the presence of antibodies against FMDV serotypes in wildlife in Uganda, serological studies were performed on buffalo serum samples collected between 2001 and 2003. Thirty-eight samples from African buffalos collected from Lake Mburo, Kidepo Valley, Murchison Falls and Queen Elizabeth National Parks were screened using Ceditest FMDV NS to detect antibodies against FMDV non-structural proteins (NSP). The seroprevalence of antibodies against non-structural proteins was 74%. To characterize FMDV antibodies, samples were selected and titrated using serotype-specific solid phase blocking enzyme linked immunosorbent assay (ELISAs). High titres of antibodies (> or =1 : 160) against FMDV serotypes SAT 1, SAT 2 and SAT 3 were identified. This study suggests that African buffalos in the different national parks in Uganda may play an important role in the epidemiology of SAT serotypes of FMDV.
AB - In East Africa, the foot-and-mouth disease (FMD) virus (FMDV) isolates have over time included serotypes O, A, C, Southern African Territories (SAT) 1 and SAT 2, mainly from livestock. SAT 3 has only been isolated in a few cases and only in African buffalos (Syncerus caffer). To investigate the presence of antibodies against FMDV serotypes in wildlife in Uganda, serological studies were performed on buffalo serum samples collected between 2001 and 2003. Thirty-eight samples from African buffalos collected from Lake Mburo, Kidepo Valley, Murchison Falls and Queen Elizabeth National Parks were screened using Ceditest FMDV NS to detect antibodies against FMDV non-structural proteins (NSP). The seroprevalence of antibodies against non-structural proteins was 74%. To characterize FMDV antibodies, samples were selected and titrated using serotype-specific solid phase blocking enzyme linked immunosorbent assay (ELISAs). High titres of antibodies (> or =1 : 160) against FMDV serotypes SAT 1, SAT 2 and SAT 3 were identified. This study suggests that African buffalos in the different national parks in Uganda may play an important role in the epidemiology of SAT serotypes of FMDV.
U2 - 10.1111/j.1865-1682.2010.01147.x
DO - 10.1111/j.1865-1682.2010.01147.x
M3 - Journal article
C2 - 20561289
SN - 1865-1674
VL - 57
SP - 286
EP - 292
JO - Transboundary and Emerging Diseases
JF - Transboundary and Emerging Diseases
IS - 4
ER -