Abstract
The potential of terahertz pulsed imaging (TPI) to predict the dissolution performance in sustained-release tablets was investigated in this study. Batches of coated tablets with similar weight gain during the coating process at the lab and pilot scales were subjected to non-destructive imaging by TPI and subsequently analysed by dissolution testing. The results from the dissolution tests revealed significant differences in the product performance between the lab and pilot scales (Student t-test, P
Originalsprog | Engelsk |
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Tidsskrift | Journal of controlled release : official journal of the Controlled Release Society |
Vol/bind | 127 |
Udgave nummer | 1 |
Sider (fra-til) | 79-87 |
Antal sider | 9 |
DOI | |
Status | Udgivet - 2008 |
Udgivet eksternt | Ja |