Abstract
Originalsprog | Engelsk |
---|---|
Tidsskrift | Cancer Causes & Control |
Vol/bind | 19 |
Udgave nummer | 3 |
Sider (fra-til) | 297-303 |
Antal sider | 6 |
ISSN | 0957-5243 |
DOI | |
Status | Udgivet - 2008 |
Bibliografisk note
Keywords: Breast Neoplasms; Female; Humans; Prognosis; Stress, Psychological; WorkAdgang til dokumentet
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Are work-related stressors associated with diagnosis of more advanced stages of incident breast cancers? / Nielsen, Naja Rod; Stahlberg, Claudia; Strandberg-Larsen, Katrine; Kristensen, Tage S; Zhang, Zuo-Feng; Hundrup, Yrsa Andersen; Grønbaek, Morten.
I: Cancer Causes & Control, Bind 19, Nr. 3, 2008, s. 297-303.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - Are work-related stressors associated with diagnosis of more advanced stages of incident breast cancers?
AU - Nielsen, Naja Rod
AU - Stahlberg, Claudia
AU - Strandberg-Larsen, Katrine
AU - Kristensen, Tage S
AU - Zhang, Zuo-Feng
AU - Hundrup, Yrsa Andersen
AU - Grønbaek, Morten
N1 - Keywords: Breast Neoplasms; Female; Humans; Prognosis; Stress, Psychological; Work
PY - 2008
Y1 - 2008
N2 - OBJECTIVE: To assess the relation between work-related stressors and breast cancer incidence and prognostic characteristics (estrogen receptor status, grade, lymph node status, size, stage) at the time of diagnosis. METHODS: The 18,932 women included in the Danish Nurse Cohort reported work-related stressors in 1993 and again in 1999 and were followed until the end of 2003 in national registries. Prognostic characteristics were obtained from a clinical database and fewer than 0.1% were lost to follow up. RESULTS: During follow-up, 455 women were diagnosed with breast cancer. Neither women with high work pressure (HR = 1.17; 95% CI: 0.79, 1.73) nor women with self-reported low influence on work organization (0.98; 0.69, 1.39) or long working hours (0.93; 0.54, 1.58) were at higher risk of breast cancer than women with no such stressors. Women with high work tempo had a slightly higher risk of breast cancer (1.25; 1.02, 1.54) than women with a suitable work tempo, but there was no dose-response effect. There were no clear differences in the prognostic characteristics of breast tumors diagnosed in women with and without work-related stressors. CONCLUSIONS: Work-related stressors do not affect breast cancer risk or the prognostic characteristics of incident breast cancers at the time of diagnosis. These results may be a comfort to working women and can hopefully prevent self-blaming among women who develop breast cancer.
AB - OBJECTIVE: To assess the relation between work-related stressors and breast cancer incidence and prognostic characteristics (estrogen receptor status, grade, lymph node status, size, stage) at the time of diagnosis. METHODS: The 18,932 women included in the Danish Nurse Cohort reported work-related stressors in 1993 and again in 1999 and were followed until the end of 2003 in national registries. Prognostic characteristics were obtained from a clinical database and fewer than 0.1% were lost to follow up. RESULTS: During follow-up, 455 women were diagnosed with breast cancer. Neither women with high work pressure (HR = 1.17; 95% CI: 0.79, 1.73) nor women with self-reported low influence on work organization (0.98; 0.69, 1.39) or long working hours (0.93; 0.54, 1.58) were at higher risk of breast cancer than women with no such stressors. Women with high work tempo had a slightly higher risk of breast cancer (1.25; 1.02, 1.54) than women with a suitable work tempo, but there was no dose-response effect. There were no clear differences in the prognostic characteristics of breast tumors diagnosed in women with and without work-related stressors. CONCLUSIONS: Work-related stressors do not affect breast cancer risk or the prognostic characteristics of incident breast cancers at the time of diagnosis. These results may be a comfort to working women and can hopefully prevent self-blaming among women who develop breast cancer.
U2 - 10.1007/s10552-007-9092-7
DO - 10.1007/s10552-007-9092-7
M3 - Journal article
C2 - 18027093
VL - 19
SP - 297
EP - 303
JO - Cancer Causes & Control
JF - Cancer Causes & Control
SN - 0957-5243
IS - 3
ER -