@article{bd3eed405d4411dd8d9f000ea68e967b,
title = "Argyrophilic nucleolar organizer regions and proliferating cell nuclear antigen/cyclin in Kaposi's sarcoma. Comparison with morphology and with immunoperoxidase staining for factor VIII-related antigen.",
abstract = "The proposal that Kaposi's sarcoma undergoes cellular transformation from early to late stages was studied with argyrophilic nucleolar organizer regions, proliferating cell nuclear antigen/cyclin, and immunoperoxidase staining for factor VIII-related antigen. Staining of argyrophilic nucleolar organizer regions was significantly increased in the plaque/nodular stage compared to the patch stage. The endothelial-selective marker factor VIII-related antigen stained more intensely in patch stage lesions. This was inversely correlated with staining of argyrophilic nucleolar organizer regions. Proliferating cell nuclear antigen/cyclin staining did not correlate with tumor stage or with factor VIII-related antigen. The changes in argyrophilic nucleolar organizer regions and factor VIII-related antigen staining are evidence for cellular transformation in Kaposi's sarcoma.",
author = "Haupt, {H M} and Stern, {J B} and H Multhaupt and Newman, {H W}",
note = "Keywords: Humans; Immunoenzyme Techniques; Nucleolus Organizer Region; Proliferating Cell Nuclear Antigen; Sarcoma, Kaposi; Silver Staining; von Willebrand Factor",
year = "1995",
language = "English",
volume = "119",
pages = "538--41",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "6",
}