TY - JOUR
T1 - Atlantinone A, a meroterpenoid produced by Penicillium ribeum and several cheese associated Penicillium species
AU - Dalsgaard, Petur Weihe
AU - Petersen, Bent
AU - Duus, Jens Ø.
AU - Zidorn, Christian
AU - Frisvad, Jens Christian
AU - Christophersen, Carsten
AU - Larsen, Thomas Ostenfeld
PY - 2012
Y1 - 2012
N2 - Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.
AB - Atlantinone A has been isolated from the psychrotolerant fungus Penicillium ribeum. The exact structure of the compound was confirmed by mass spectrometric and 1- and 2D NMR experiments. Atlantinone A was originally only produced upon chemical epigenetic manipulation of P. hirayamae, however in this study the compound was found to be produced at standard growth conditions by the following species; P. solitum, P. discolor, P. commune, P. caseifulvum, P. palitans, P. novae-zeelandiae and P. monticola. A biosynthetic pathway to atlantinone A starting from andrastin A is proposed.
KW - biology
M3 - Journal article
VL - 2
SP - 214
EP - 220
JO - Metabolites
JF - Metabolites
SN - 2218-1989
IS - 1
ER -