Authentication and assessment of contamination in ancient DNA

Gabriel Renaud, Mikkel Schubert, Susanna Sawyer, Ludovic Orlando*

*Corresponding author af dette arbejde

Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningpeer review

20 Citationer (Scopus)
524 Downloads (Pure)

Abstract

Contamination from both present-day humans and postmortem microbial sources is a common challenge in ancient DNA studies. Here we present a suite of tools to assist in the assessment of contamination in ancient DNA data sets. These tools perform standard tests of authenticity of ancient DNA data including detecting the presence of postmortem damage signatures in sequence alignments and quantifying the amount of present-day human contamination.

OriginalsprogEngelsk
TitelAncient DNA : Methods and Protocols
RedaktørerBeth Shapiro, Axel Barlow, Peter D. Heintzman, Michael Hofreiter, Johanna L. A. Paijmans, André E. R. Soares
Antal sider32
ForlagHumana Press
Publikationsdato2019
Udgave2. ed.
Sider163-194
Kapitel17
ISBN (Trykt) 978-1-4939-9175-4
ISBN (Elektronisk)978-1-4939-9176-1
DOI
StatusUdgivet - 2019
NavnMethods in Molecular Biology
Vol/bind1963
ISSN1064-3745

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