BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania

Daniel Faurholt-Jepsen, Nyagosya Range, George PrayGod, Kidola Jeremiah, Maria Faurholt-Jepsen, Martine G Aabye, Harleen M S Grewal, John Changalucha, Daniel R Witte, Aase B Andersen, Henrik Friis

Publikation: Bidrag til tidsskriftLetterForskningpeer review

17 Citationer (Scopus)

Abstract

While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.
OriginalsprogEngelsk
TidsskriftThorax
Vol/bind68
Udgave nummer3
Sider (fra-til)288-289
Antal sider2
ISSN0040-6376
DOI
StatusUdgivet - 2013

Bibliografisk note

CURIS 2013 NEXS 044

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