Behandling af våd aldersrelateret makuladegeneration med vaskulaer endotel vaekstfaktorhaemmer. Gennemgang af et Cochrane-review

Sara Brandi Bloch; Michael Larsen; Sara Brandi Bloch; Michael Larsen

Behandling af våd aldersrelateret makuladegeneration med vaskulaer endotel vaekstfaktorhaemmer. Gennemgang af et Cochrane-review

Sara Brandi Bloch
, Michael Larsen
, Sara Brandi Bloch
, Michael Larsen

Publikation: Bidrag til tidsskrift › Review › peer review

Abstract

This evaluation of a Cochrane-review including five clinical trials of good methodological quality indicates that the antiangiogenic therapeutic agents, pegaptanib and ranibizumab, are effective treatment strategies for neovascular Age-Related Macular Degeneration (AMD). The review does not include a direct comparison or an indirect statistical comparison between the two antiangiogenic agents. In clinical practice ranibizumab compared to pegaptanib is the drug of choice because of cost-utility analysis and the number of patients gaining visual acuity.
Udgivelsesdato: 2009-Nov

Bidragets oversatte titel	Treatment of wet age-related macular degeneration with vascular endothelial growth factor. A survey of a Cochrane review
Originalsprog	Dansk
Tidsskrift	Ugeskrift for læger
Vol/bind	171
Udgave nummer	47
Sider (fra-til)	3435-7
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 16 nov. 2009

Bibliografisk note

Keywords: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Aptamers, Nucleotide; Evidence-Based Medicine; Humans; Porphyrins; Treatment Outcome; Vascular Endothelial Growth Factor A; Wet Macular Degeneration

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Citationsformater

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AU - Bloch, Sara Brandi

AU - Larsen, Michael

AU - Bloch, Sara Brandi

AU - Larsen, Michael

N1 - Keywords: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Aptamers, Nucleotide; Evidence-Based Medicine; Humans; Porphyrins; Treatment Outcome; Vascular Endothelial Growth Factor A; Wet Macular Degeneration

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AB - This evaluation of a Cochrane-review including five clinical trials of good methodological quality indicates that the antiangiogenic therapeutic agents, pegaptanib and ranibizumab, are effective treatment strategies for neovascular Age-Related Macular Degeneration (AMD). The review does not include a direct comparison or an indirect statistical comparison between the two antiangiogenic agents. In clinical practice ranibizumab compared to pegaptanib is the drug of choice because of cost-utility analysis and the number of patients gaining visual acuity. Udgivelsesdato: 2009-Nov

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