Catecholamines in plasma from artery, cubital vein, and femoral vein in patients with cirrhosis. Significance of sampling site

Jens Henrik Sahl Henriksen; H Ring-Larsen; N J Christensen

Catecholamines in plasma from artery, cubital vein, and femoral vein in patients with cirrhosis. Significance of sampling site

Jens Henrik Sahl Henriksen, H Ring-Larsen, N J Christensen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

22 Citationer (Scopus)

Abstract

Udgivelsesdato: 1986-Feb

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Clinical & Laboratory Investigation
Vol/bind	46
Udgave nummer	1
Sider (fra-til)	39-44
Antal sider	5
ISSN	0036-5513
Status	Udgivet - 1986

Bibliografisk note

Keywords: Adult; Aged; Arteries; Blood Specimen Collection; Elbow; Epinephrine; Female; Femoral Vein; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Norepinephrine; Vascular Resistance; Veins

Citationsformater

Catecholamines in plasma from artery, cubital vein, and femoral vein in patients with cirrhosis. Significance of sampling site. / Henriksen, Jens Henrik Sahl; Ring-Larsen, H; Christensen, N J.
I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 46, Nr. 1, 1986, s. 39-44.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

@article{509bf88038d611dfad7f000ea68e967b,

title = "Catecholamines in plasma from artery, cubital vein, and femoral vein in patients with cirrhosis. Significance of sampling site",

abstract = "The concentration of noradrenaline (NA) and adrenaline (A) was measured in arterial, cubital venous and femoral venous plasma in order to determine possible differences in different vascular beds in the peripheral circulation. In patients with cirrhosis, arterial plasma NA (median 2.54 nmol/l, n = 40) was significantly increased compared to controls (median 1.42 nmol/l, n = 17, p less than 0.001). Arterial plasma A was not significantly different (0.41 vs. 0.38 nmol/l). Cubital and femoral venous NA and A were positively correlated to the arterial values in both cirrhosis and controls (r = 0.86 to 0.97, p less than 0.01). In cirrhosis, median cubital venous:arterial NA ratio was significantly above unity (1.14, n = 36, p less than 0.001) as compared to unity in controls (1.00, n = 8), whereas the femoral venous:arterial NA ratio was similar in cirrhosis and controls, and significantly below unity (median 0.86 and 0.87). Cubital venous:arterial and femoral venous:arterial A ratios were significantly below unity in cirrhosis as well as in controls. The results point towards an enhanced sympathetic nervous activity in cirrhosis which may involve, among other organs, the upper limb (especially the skin of forearm and hand). To assess circulating levels of catecholamines, the importance of arterial sampling is stressed as peripheral venous samples may also reflect local factors.",

author = "Henriksen, {Jens Henrik Sahl} and H Ring-Larsen and Christensen, {N J}",

note = "Keywords: Adult; Aged; Arteries; Blood Specimen Collection; Elbow; Epinephrine; Female; Femoral Vein; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Norepinephrine; Vascular Resistance; Veins",

year = "1986",

language = "English",

volume = "46",

pages = "39--44",

journal = "Scandinavian Journal of Clinical & Laboratory Investigation",

issn = "0036-5513",

publisher = "Taylor & Francis",

number = "1",

}

TY - JOUR

T1 - Catecholamines in plasma from artery, cubital vein, and femoral vein in patients with cirrhosis. Significance of sampling site

AU - Henriksen, Jens Henrik Sahl

AU - Ring-Larsen, H

AU - Christensen, N J

N1 - Keywords: Adult; Aged; Arteries; Blood Specimen Collection; Elbow; Epinephrine; Female; Femoral Vein; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Norepinephrine; Vascular Resistance; Veins

PY - 1986

Y1 - 1986

N2 - The concentration of noradrenaline (NA) and adrenaline (A) was measured in arterial, cubital venous and femoral venous plasma in order to determine possible differences in different vascular beds in the peripheral circulation. In patients with cirrhosis, arterial plasma NA (median 2.54 nmol/l, n = 40) was significantly increased compared to controls (median 1.42 nmol/l, n = 17, p less than 0.001). Arterial plasma A was not significantly different (0.41 vs. 0.38 nmol/l). Cubital and femoral venous NA and A were positively correlated to the arterial values in both cirrhosis and controls (r = 0.86 to 0.97, p less than 0.01). In cirrhosis, median cubital venous:arterial NA ratio was significantly above unity (1.14, n = 36, p less than 0.001) as compared to unity in controls (1.00, n = 8), whereas the femoral venous:arterial NA ratio was similar in cirrhosis and controls, and significantly below unity (median 0.86 and 0.87). Cubital venous:arterial and femoral venous:arterial A ratios were significantly below unity in cirrhosis as well as in controls. The results point towards an enhanced sympathetic nervous activity in cirrhosis which may involve, among other organs, the upper limb (especially the skin of forearm and hand). To assess circulating levels of catecholamines, the importance of arterial sampling is stressed as peripheral venous samples may also reflect local factors.

AB - The concentration of noradrenaline (NA) and adrenaline (A) was measured in arterial, cubital venous and femoral venous plasma in order to determine possible differences in different vascular beds in the peripheral circulation. In patients with cirrhosis, arterial plasma NA (median 2.54 nmol/l, n = 40) was significantly increased compared to controls (median 1.42 nmol/l, n = 17, p less than 0.001). Arterial plasma A was not significantly different (0.41 vs. 0.38 nmol/l). Cubital and femoral venous NA and A were positively correlated to the arterial values in both cirrhosis and controls (r = 0.86 to 0.97, p less than 0.01). In cirrhosis, median cubital venous:arterial NA ratio was significantly above unity (1.14, n = 36, p less than 0.001) as compared to unity in controls (1.00, n = 8), whereas the femoral venous:arterial NA ratio was similar in cirrhosis and controls, and significantly below unity (median 0.86 and 0.87). Cubital venous:arterial and femoral venous:arterial A ratios were significantly below unity in cirrhosis as well as in controls. The results point towards an enhanced sympathetic nervous activity in cirrhosis which may involve, among other organs, the upper limb (especially the skin of forearm and hand). To assess circulating levels of catecholamines, the importance of arterial sampling is stressed as peripheral venous samples may also reflect local factors.

M3 - Journal article

C2 - 3952439

SN - 0036-5513

VL - 46

SP - 39

EP - 44

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

IS - 1

ER -