Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019

Anne Line Engsbro, Hans Søe Riis Jespersen, Maria Ingeborg Goldschmidt, Sarah Mollerup, Peder Worning, Martin Schou Pedersen, Henrik Westh, Uffe Vest Schneider

Publikation: Bidrag til tidsskriftLetterForskningpeer review

23 Citationer (Scopus)
18 Downloads (Pure)

Abstract

We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.

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