TY - JOUR
T1 - Cerebral FDG-PET scanning abnormalities in optimally treated HIV patients
AU - Andersen, Åse Bengård
AU - Law, Ian
AU - Krabbe, Karen Suarez
AU - Kemp Bruunsgaard, Helle
AU - Ostrowski, Sisse R
AU - Ullum, Henrik
AU - Højgaard, Liselotte
AU - Lebech, Annemette
AU - Gerstoft, Jan
AU - Kjær, Andreas
PY - 2010/1/1
Y1 - 2010/1/1
N2 - The long-term neurological consequences of HIV infection and treatment are not yet completely understood. In this study we examined the prevalence of cerebral metabolic abnormalities among a cohort of neurologically intact HIV patients with fully suppressed HIV viral loads. Concomitant analyses of circulating brain derived neurotrophic factor (BDNF) were performed to correlate these abnormalities with potential signs of neuro-regenerating/protective activity, and concomitant analyses of circulating tumour necrosis factor (TNF) alpha, interleukin (IL) 6, and soluble urokinase plasminogen activator receptor (suPAR) were performed to correlate these abnormalities with potential signs of neurodegenerative processes.
AB - The long-term neurological consequences of HIV infection and treatment are not yet completely understood. In this study we examined the prevalence of cerebral metabolic abnormalities among a cohort of neurologically intact HIV patients with fully suppressed HIV viral loads. Concomitant analyses of circulating brain derived neurotrophic factor (BDNF) were performed to correlate these abnormalities with potential signs of neuro-regenerating/protective activity, and concomitant analyses of circulating tumour necrosis factor (TNF) alpha, interleukin (IL) 6, and soluble urokinase plasminogen activator receptor (suPAR) were performed to correlate these abnormalities with potential signs of neurodegenerative processes.
U2 - http://dx.doi.org/10.1186/1742-2094-7-13
DO - http://dx.doi.org/10.1186/1742-2094-7-13
M3 - Journal article
VL - 7
SP - 13
JO - Journal of Neuroinflammation
JF - Journal of Neuroinflammation
SN - 1742-2094
ER -