Cerebral gray and white matter changes and clinical course in metachromatic leukodystrophy

Samuel Groeschel; Christine í Dali; Philipp Clas; Judith Böhringer; Morten Duno; Christian Krarup; Christiane Kehrer; Marko Wilke; Ingeborg Krägeloh-Mann

doi:10.1212/WNL.0b013e31826e9ad2

Cerebral gray and white matter changes and clinical course in metachromatic leukodystrophy

Samuel Groeschel, Christine í Dali, Philipp Clas, Judith Böhringer, Morten Duno, Christian Krarup, Christiane Kehrer, Marko Wilke, Ingeborg Krägeloh-Mann

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

40 Citationer (Scopus)

Abstract

Metachromatic leukodystrophy (MLD) is a rare metabolic disorder leading to demyelination and rapid neurologic deterioration. As therapeutic options evolve, it seems essential to understand and quantify progression of the natural disease. The aim of this study was to assess cerebral volumetric changes in children with MLD in comparison to normal controls and in relation to disease course.

Originalsprog	Engelsk
Tidsskrift	Neurology
Vol/bind	79
Udgave nummer	16
Sider (fra-til)	1662-70
Antal sider	9
ISSN	0028-3878
DOI	https://doi.org/10.1212/WNL.0b013e31826e9ad2
Status	Udgivet - 2012
Udgivet eksternt	Ja

Adgang til dokumentet

10.1212/WNL.0b013e31826e9ad2

Citationsformater

Cerebral gray and white matter changes and clinical course in metachromatic leukodystrophy. / Groeschel, Samuel; í Dali, Christine; Clas, Philipp; Böhringer, Judith; Duno, Morten; Krarup, Christian; Kehrer, Christiane; Wilke, Marko; Krägeloh-Mann, Ingeborg.

I: Neurology, Bind 79, Nr. 16, 2012, s. 1662-70.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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abstract = "Metachromatic leukodystrophy (MLD) is a rare metabolic disorder leading to demyelination and rapid neurologic deterioration. As therapeutic options evolve, it seems essential to understand and quantify progression of the natural disease. The aim of this study was to assess cerebral volumetric changes in children with MLD in comparison to normal controls and in relation to disease course.",

author = "Samuel Groeschel and {{\'i} Dali}, Christine and Philipp Clas and Judith B{\"o}hringer and Morten Duno and Christian Krarup and Christiane Kehrer and Marko Wilke and Ingeborg Kr{\"a}geloh-Mann",

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AU - Duno, Morten

AU - Krarup, Christian

AU - Kehrer, Christiane

AU - Wilke, Marko

AU - Krägeloh-Mann, Ingeborg

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AB - Metachromatic leukodystrophy (MLD) is a rare metabolic disorder leading to demyelination and rapid neurologic deterioration. As therapeutic options evolve, it seems essential to understand and quantify progression of the natural disease. The aim of this study was to assess cerebral volumetric changes in children with MLD in comparison to normal controls and in relation to disease course.

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