Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigation

Jason Schiffman; Elaine Walker; Morten Ekstrøm; Fini Schulsinger; Holger Jelling Sørensen; Sarnoff Mednick

doi:10.1176/appi.ajp.161.11.2021

Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigation

Jason Schiffman, Elaine Walker, Morten Ekstrøm, Fini Schulsinger, Holger Jelling Sørensen, Sarnoff Mednick

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

132 Citationer (Scopus)

Abstract

Udgivelsesdato: 2004-Nov

Originalsprog	Engelsk
Tidsskrift	American Journal of Psychiatry
Vol/bind	161
Udgave nummer	11
Sider (fra-til)	2021-7
Antal sider	6
ISSN	0002-953X
DOI	https://doi.org/10.1176/appi.ajp.161.11.2021
Status	Udgivet - 2004

Bibliografisk note

Keywords: Adolescent; Adult; Age Factors; Child; Child of Impaired Parents; Comorbidity; Denmark; Developmental Disabilities; Female; Humans; Male; Mental Disorders; Prospective Studies; Psychomotor Disorders; Risk Factors; Schizophrenia; Social Adjustment; Social Behavior Disorders; Videotape Recording

Adgang til dokumentet

10.1176/appi.ajp.161.11.2021

Citationsformater

@article{431207e518e64a99a855ecc096e6c269,

title = "Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigation",

abstract = "OBJECTIVE: The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia. METHOD: In 1972, a sample of 265 11-13-year-old Danish children were filmed under standardized conditions while they were eating lunch. The examination was part of a larger study investigating early signs of schizophrenia spectrum disorders. Many of the subjects had a parent with schizophrenia, leaving them at high risk for developing a schizophrenia spectrum disorder. In 1991, adult psychiatric outcome data were obtained for 91.3% (N=242). This study systematically analyzed the videotapes to determine whether the children who developed schizophrenia as adults evidenced greater social and/or neuromotor deficits than children who did not develop a psychiatric disorder and children who developed other psychiatric disorders. RESULTS: The findings from this study suggest that the brief videotaped footage of children eating lunch was able to discriminate between the individuals who later developed schizophrenia and those who did not. Specifically, the preschizophrenia children evidenced differences on measures of sociability and general neuromotor functioning (among boys) from the children who developed other psychiatric disorders and the children who did not develop a psychiatric disorder. CONCLUSIONS: Social and neuromotor deficits specific to children who develop schizophrenia in adulthood provide further support for a neurodevelopmental hypothesis of schizophrenia.",

author = "Jason Schiffman and Elaine Walker and Morten Ekstr{\o}m and Fini Schulsinger and S{\o}rensen, {Holger Jelling} and Sarnoff Mednick",

note = "Keywords: Adolescent; Adult; Age Factors; Child; Child of Impaired Parents; Comorbidity; Denmark; Developmental Disabilities; Female; Humans; Male; Mental Disorders; Prospective Studies; Psychomotor Disorders; Risk Factors; Schizophrenia; Social Adjustment; Social Behavior Disorders; Videotape Recording",

year = "2004",

doi = "10.1176/appi.ajp.161.11.2021",

language = "English",

volume = "161",

pages = "2021--7",

journal = "American Journal of Psychiatry",

issn = "0002-953X",

publisher = "American Psychiatric Publishing, Inc.",

number = "11",

}

TY - JOUR

T1 - Childhood videotaped social and neuromotor precursors of schizophrenia: a prospective investigation

AU - Schiffman, Jason

AU - Walker, Elaine

AU - Ekstrøm, Morten

AU - Schulsinger, Fini

AU - Sørensen, Holger Jelling

AU - Mednick, Sarnoff

N1 - Keywords: Adolescent; Adult; Age Factors; Child; Child of Impaired Parents; Comorbidity; Denmark; Developmental Disabilities; Female; Humans; Male; Mental Disorders; Prospective Studies; Psychomotor Disorders; Risk Factors; Schizophrenia; Social Adjustment; Social Behavior Disorders; Videotape Recording

PY - 2004

Y1 - 2004

N2 - OBJECTIVE: The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia. METHOD: In 1972, a sample of 265 11-13-year-old Danish children were filmed under standardized conditions while they were eating lunch. The examination was part of a larger study investigating early signs of schizophrenia spectrum disorders. Many of the subjects had a parent with schizophrenia, leaving them at high risk for developing a schizophrenia spectrum disorder. In 1991, adult psychiatric outcome data were obtained for 91.3% (N=242). This study systematically analyzed the videotapes to determine whether the children who developed schizophrenia as adults evidenced greater social and/or neuromotor deficits than children who did not develop a psychiatric disorder and children who developed other psychiatric disorders. RESULTS: The findings from this study suggest that the brief videotaped footage of children eating lunch was able to discriminate between the individuals who later developed schizophrenia and those who did not. Specifically, the preschizophrenia children evidenced differences on measures of sociability and general neuromotor functioning (among boys) from the children who developed other psychiatric disorders and the children who did not develop a psychiatric disorder. CONCLUSIONS: Social and neuromotor deficits specific to children who develop schizophrenia in adulthood provide further support for a neurodevelopmental hypothesis of schizophrenia.

AB - OBJECTIVE: The authors examined videotaped behaviors of children who developed schizophrenia as adults and of comparison subjects to disclose possible social and neuromotor deficits foreshadowing later development of schizophrenia. METHOD: In 1972, a sample of 265 11-13-year-old Danish children were filmed under standardized conditions while they were eating lunch. The examination was part of a larger study investigating early signs of schizophrenia spectrum disorders. Many of the subjects had a parent with schizophrenia, leaving them at high risk for developing a schizophrenia spectrum disorder. In 1991, adult psychiatric outcome data were obtained for 91.3% (N=242). This study systematically analyzed the videotapes to determine whether the children who developed schizophrenia as adults evidenced greater social and/or neuromotor deficits than children who did not develop a psychiatric disorder and children who developed other psychiatric disorders. RESULTS: The findings from this study suggest that the brief videotaped footage of children eating lunch was able to discriminate between the individuals who later developed schizophrenia and those who did not. Specifically, the preschizophrenia children evidenced differences on measures of sociability and general neuromotor functioning (among boys) from the children who developed other psychiatric disorders and the children who did not develop a psychiatric disorder. CONCLUSIONS: Social and neuromotor deficits specific to children who develop schizophrenia in adulthood provide further support for a neurodevelopmental hypothesis of schizophrenia.

U2 - 10.1176/appi.ajp.161.11.2021

DO - 10.1176/appi.ajp.161.11.2021

M3 - Journal article

SN - 0002-953X

VL - 161

SP - 2021

EP - 2027

JO - American Journal of Psychiatry

JF - American Journal of Psychiatry

IS - 11

ER -