Cimetidine treatment of protein-losing gastropathy (Ménétrier's disease). A clinical and pathophysiological study

E Krag; H J Frederiksen; N Olsen; Jens Henrik Sahl Henriksen

Cimetidine treatment of protein-losing gastropathy (Ménétrier's disease). A clinical and pathophysiological study

E Krag, H J Frederiksen, N Olsen, Jens Henrik Sahl Henriksen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

38 Citationer (Scopus)

Abstract

Udgivelsesdato: 1978-null

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Gastroenterology
Vol/bind	13
Udgave nummer	5
Sider (fra-til)	636-9
Antal sider	3
ISSN	0036-5521
Status	Udgivet - 1978

Bibliografisk note

Keywords: Cimetidine; Guanidines; Humans; Intestinal Absorption; Male; Membrane Potentials; Middle Aged; Protein-Losing Enteropathies; Proteins; Water-Electrolyte Balance

Citationsformater

@article{e496fdd04e1311df928f000ea68e967b,

title = "Cimetidine treatment of protein-losing gastropathy (M{\'e}n{\'e}trier's disease). A clinical and pathophysiological study",

abstract = "In a 47-year-old male with M{\'e}n{\'e}trier's disease (protein-losing gastropathy) the histamine-H2-receptor antagonist Cimetidine stops the protein loss and improves the clinical condition. Gastric perfusion studies on net and bidirectional ionic fluxes, protein secretion rates, and permeability, with simultaneous recording of the transmural electrical potential difference indicate that Cimetidine decreases a paracellular protein secretion by 'tightening' the tight junctions of the gastric epithelium.",

author = "E Krag and Frederiksen, {H J} and N Olsen and Henriksen, {Jens Henrik Sahl}",

note = "Keywords: Cimetidine; Guanidines; Humans; Intestinal Absorption; Male; Membrane Potentials; Middle Aged; Protein-Losing Enteropathies; Proteins; Water-Electrolyte Balance",

year = "1978",

language = "English",

volume = "13",

pages = "636--9",

journal = "Scandinavian Journal of Gastroenterology",

issn = "0036-5521",

publisher = "Taylor & Francis",

number = "5",

}

TY - JOUR

T1 - Cimetidine treatment of protein-losing gastropathy (Ménétrier's disease). A clinical and pathophysiological study

AU - Krag, E

AU - Frederiksen, H J

AU - Olsen, N

AU - Henriksen, Jens Henrik Sahl

N1 - Keywords: Cimetidine; Guanidines; Humans; Intestinal Absorption; Male; Membrane Potentials; Middle Aged; Protein-Losing Enteropathies; Proteins; Water-Electrolyte Balance

PY - 1978

Y1 - 1978

N2 - In a 47-year-old male with Ménétrier's disease (protein-losing gastropathy) the histamine-H2-receptor antagonist Cimetidine stops the protein loss and improves the clinical condition. Gastric perfusion studies on net and bidirectional ionic fluxes, protein secretion rates, and permeability, with simultaneous recording of the transmural electrical potential difference indicate that Cimetidine decreases a paracellular protein secretion by 'tightening' the tight junctions of the gastric epithelium.

AB - In a 47-year-old male with Ménétrier's disease (protein-losing gastropathy) the histamine-H2-receptor antagonist Cimetidine stops the protein loss and improves the clinical condition. Gastric perfusion studies on net and bidirectional ionic fluxes, protein secretion rates, and permeability, with simultaneous recording of the transmural electrical potential difference indicate that Cimetidine decreases a paracellular protein secretion by 'tightening' the tight junctions of the gastric epithelium.

M3 - Journal article

C2 - 705259

SN - 0036-5521

VL - 13

SP - 636

EP - 639

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

IS - 5

ER -