Collagenous Colitis: Are Bacterial Cytotoxins Responsible?

Teis Andersen; Jens Rikardt Andersen; Michael Tvede; Maria‐Benedicte ‐B Franzmann

doi:10.1111/j.1572-0241.1993.tb07549.x

Collagenous Colitis: Are Bacterial Cytotoxins Responsible?

Teis Andersen^*, Jens Rikardt Andersen, Michael Tvede, Maria‐Benedicte ‐B Franzmann

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

96 Citationer (Scopus)

Abstract

In a case of collagenous colitis, cholestyramine treatment resulted in symptomatic and histological normalization. After discontinuation of cholestyramine, collagenous colitis relapsed. At this time fecal cytotoxic activity was demonstrated in McCoy cell lines. Symptoms, histologic changes, and cytotoxicity disappeared when cholestyramine treatment was reinstituted. We hypothesize that a bacterial toxin is responsible for the development of collagenous colitis.

Originalsprog	Engelsk
Tidsskrift	The American Journal of Gastroenterology
Vol/bind	88
Udgave nummer	3
Sider (fra-til)	375-377
Antal sider	3
ISSN	0002-9270
DOI	https://doi.org/10.1111/j.1572-0241.1993.tb07549.x
Status	Udgivet - mar. 1993

Adgang til dokumentet

10.1111/j.1572-0241.1993.tb07549.x

Citationsformater

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title = "Collagenous Colitis: Are Bacterial Cytotoxins Responsible?",

abstract = "In a case of collagenous colitis, cholestyramine treatment resulted in symptomatic and histological normalization. After discontinuation of cholestyramine, collagenous colitis relapsed. At this time fecal cytotoxic activity was demonstrated in McCoy cell lines. Symptoms, histologic changes, and cytotoxicity disappeared when cholestyramine treatment was reinstituted. We hypothesize that a bacterial toxin is responsible for the development of collagenous colitis.",

author = "Teis Andersen and Andersen, {Jens Rikardt} and Michael Tvede and Franzmann, {Maria‐Benedicte ‐B}",

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AU - Tvede, Michael

AU - Franzmann, Maria‐Benedicte ‐B

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N2 - In a case of collagenous colitis, cholestyramine treatment resulted in symptomatic and histological normalization. After discontinuation of cholestyramine, collagenous colitis relapsed. At this time fecal cytotoxic activity was demonstrated in McCoy cell lines. Symptoms, histologic changes, and cytotoxicity disappeared when cholestyramine treatment was reinstituted. We hypothesize that a bacterial toxin is responsible for the development of collagenous colitis.

AB - In a case of collagenous colitis, cholestyramine treatment resulted in symptomatic and histological normalization. After discontinuation of cholestyramine, collagenous colitis relapsed. At this time fecal cytotoxic activity was demonstrated in McCoy cell lines. Symptoms, histologic changes, and cytotoxicity disappeared when cholestyramine treatment was reinstituted. We hypothesize that a bacterial toxin is responsible for the development of collagenous colitis.

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