Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

Karlis Berzins; Sara J. Fraser-Miller; Rong Di; Jingwen Liu; Leena Peltonen; Clare J. Strachan; Thomas Rades; Keith C. Gordon

doi:10.1021/acs.molpharmaceut.0c01208

Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

Karlis Berzins, Sara J. Fraser-Miller, Rong Di, Jingwen Liu, Leena Peltonen, Clare J. Strachan, Thomas Rades, Keith C. Gordon

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

8 Citationer (Scopus)

50 Downloads (Pure)

Originalsprog	Engelsk
Tidsskrift	Molecular Pharmaceutics
Vol/bind	18
Udgave nummer	3
Sider (fra-til)	1408-1418
ISSN	1543-8384
DOI	https://doi.org/10.1021/acs.molpharmaceut.0c01208
Status	Udgivet - 2021

Adgang til dokumentet

10.1021/acs.molpharmaceut.0c01208

FulltextAccepteret manuskript, 1,7 MBLicens: CC BY-NC

Citationsformater

@article{fc50b0c325f0462185aba0491dc77ecf,

title = "Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib",

keywords = "celecoxib, amorphous drugs, compression-induced destabilization, low-frequency Raman spectroscopy, dissolution",

author = "Karlis Berzins and Fraser-Miller, {Sara J.} and Rong Di and Jingwen Liu and Leena Peltonen and Strachan, {Clare J.} and Thomas Rades and Gordon, {Keith C.}",

year = "2021",

doi = "10.1021/acs.molpharmaceut.0c01208",

language = "English",

volume = "18",

pages = "1408--1418",

journal = "Molecular Pharmaceutics",

issn = "1543-8384",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib

AU - Berzins, Karlis

AU - Fraser-Miller, Sara J.

AU - Di, Rong

AU - Liu, Jingwen

AU - Peltonen, Leena

AU - Strachan, Clare J.

AU - Rades, Thomas

AU - Gordon, Keith C.

PY - 2021

Y1 - 2021

KW - celecoxib

KW - amorphous drugs

KW - compression-induced destabilization

KW - low-frequency Raman spectroscopy

KW - dissolution

U2 - 10.1021/acs.molpharmaceut.0c01208

DO - 10.1021/acs.molpharmaceut.0c01208

M3 - Journal article

C2 - 33586988

SN - 1543-8384

VL - 18

SP - 1408

EP - 1418

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 3

ER -