Abstract
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | European Journal of Heart Failure |
| Vol/bind | 5 |
| Udgave nummer | 6 |
| Sider (fra-til) | 811-9 |
| Antal sider | 8 |
| ISSN | 1388-9842 |
| Status | Udgivet - 2003 |
Bibliografisk note
Keywords: Aged; Aged, 80 and over; Blood Pressure; Denmark; Echocardiography; Female; Heart Failure; Hospitalization; Humans; Male; Mass Screening; Middle Aged; Myocardial Infarction; Prevalence; Prognosis; Prospective Studies; Survival Rate; Ventricular Dysfunction, LeftCitationsformater
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I: European Journal of Heart Failure, Bind 5, Nr. 6, 2003, s. 811-9.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - Congestive heart failure with preserved left ventricular systolic function after acute myocardial infarction: clinical and prognostic implications
AU - Møller, Jacob Eifer
AU - Brendorp, Bente
AU - Ottesen, Michael
AU - Køber, Lars
AU - Egstrup, Kenneth
AU - Poulsen, Steen Hvitfelt
AU - Torp-Pedersen, Christian
AU - Bucindolol Evaluation in Acute Myocardial Infarction Trail Group
N1 - Keywords: Aged; Aged, 80 and over; Blood Pressure; Denmark; Echocardiography; Female; Heart Failure; Hospitalization; Humans; Male; Mass Screening; Middle Aged; Myocardial Infarction; Prevalence; Prognosis; Prospective Studies; Survival Rate; Ventricular Dysfunction, Left
PY - 2003
Y1 - 2003
N2 - AIMS: To characterise the prevalence, in-hospital complications, management, and long-term outcome of patients with congestive heart failure but preserved left ventricular systolic function after acute myocardial infarction. METHODS: 3166 consecutive patients screened for entry in the Bucindolol Evaluation in Acute Myocardial Infarction Trial with definite acute myocardial infarction and echocardiographic assessment of left ventricular systolic function were included between 1998 and 1999 in this prospective observational study. Main outcome measures were occurrences of in-hospital complications and all cause mortality. RESULTS: Congestive heart failure was seen during hospitalisation in 1464 patients (46%), 717 patients had preserved left ventricular systolic function (wall motion index > or =1.3 corresponding to ejection fraction > or =0.40), and 732 patients had systolic dysfunction (wall motion index <1.3). One year mortality in patients with no heart failure, heart failure with preserved systolic function, and heart failure with systolic dysfunction were 6, 22 and 35%, P<0.0001. Unadjusted risk of death from all causes associated with heart failure and preserved systolic function was 3.3 (95% CI 2.8-4.0), and after adjustment for baseline characteristics and left ventricular systolic function in multivariate Cox proportional hazards analysis the risk was 2.1 (95% CI 1.7-2.6), P<0.0001. CONCLUSIONS: Congestive heart failure is frequently present in patients with preserved left ventricular systolic function, and is associated with increased risk of in-hospital complications and death following acute myocardial infarction.
AB - AIMS: To characterise the prevalence, in-hospital complications, management, and long-term outcome of patients with congestive heart failure but preserved left ventricular systolic function after acute myocardial infarction. METHODS: 3166 consecutive patients screened for entry in the Bucindolol Evaluation in Acute Myocardial Infarction Trial with definite acute myocardial infarction and echocardiographic assessment of left ventricular systolic function were included between 1998 and 1999 in this prospective observational study. Main outcome measures were occurrences of in-hospital complications and all cause mortality. RESULTS: Congestive heart failure was seen during hospitalisation in 1464 patients (46%), 717 patients had preserved left ventricular systolic function (wall motion index > or =1.3 corresponding to ejection fraction > or =0.40), and 732 patients had systolic dysfunction (wall motion index <1.3). One year mortality in patients with no heart failure, heart failure with preserved systolic function, and heart failure with systolic dysfunction were 6, 22 and 35%, P<0.0001. Unadjusted risk of death from all causes associated with heart failure and preserved systolic function was 3.3 (95% CI 2.8-4.0), and after adjustment for baseline characteristics and left ventricular systolic function in multivariate Cox proportional hazards analysis the risk was 2.1 (95% CI 1.7-2.6), P<0.0001. CONCLUSIONS: Congestive heart failure is frequently present in patients with preserved left ventricular systolic function, and is associated with increased risk of in-hospital complications and death following acute myocardial infarction.
M3 - Journal article
C2 - 14675860
SN - 1388-9842
VL - 5
SP - 811
EP - 819
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
IS - 6
ER -