TY - JOUR
T1 - Copenhagen pancreatitis study
T2 - An interim report from a prospective epidemiological multicentre study
AU - Andersen, Jens Rikardt
AU - Backer, O
AU - Balsløv, J T
AU - Bonnevie, O.
AU - Burcharth, F
AU - Christoffersen, I
AU - Christoffersen, P
AU - Clausen, B
AU - Ehlers, D
AU - Fischermann, K
AU - Frederiksen, H J
AU - Friedberg, R
AU - Hamilton, B
AU - Hardt, F
AU - Hegnhøj, J
AU - Jarnum, S
AU - Jensen, H E
AU - Jess, P
AU - Justesen, T
AU - Kjærgaard, J
AU - Klarskov, P
AU - Krag, E
AU - Madsen, P
AU - Magid, E
AU - Malchow-Møller, A
AU - Marcussen, H
AU - Matzen, P
AU - Nørgaard, B.
AU - Pedersen-Bjergaard, O
AU - Raahave, D
AU - Schmidt, A
AU - Stigsby, B
AU - Teilum, D
AU - Uhrenholdt, A
AU - Villumsen, B
AU - Winkler, K
AU - The Copenhagen Pancreatitis Study Group
N1 - (Ekstern)
PY - 1981
Y1 - 1981
N2 - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.
AB - During the past 2 decades an increasing number of patients with pancreatitis have been admitted to the Copenhagen hospitals. For this reason all departments receiving such patients from the city of Copenhagen initiated the Copenhagen Pancreatitis Study (CPS), to provide a prospective recording of all pancreatitis patients from this geographical area and to conduct yearly follow-up studies of the patients. The aims of the CPS were, first, to establish data on the incidence, prevalence, and clinical characteristics of pancreatitis, and, second, to evaluate the accuracy of diagnostic tests applied and to provide data on the natural history and the prognosis under current therapy. The present study is an interim report on 343 patients from the initial 1 1/2 years of the CPS. Pancreatitis patients are listed in four diagnostic groups: I. Possible acute pancreatitis; II. Acute pancreatitis; III. Possible chronic pancreatitis; IV. Chronic pancreatitis. The incidence rates per year per 100,000 citizens aged 20 years or more (population aged 20 years or more: 417,000) were as follows: total, 36.3; I, 6.2; II, 21.9; III, 4.2; IV, 4.0. The prevalence for the chronic types on 31 August 1979 per 100,000 citizens aged 20 years or more was as follows: total, 27.4; III, 14.4; IV, 13.0. Gallstones were found in 1/3 of the acute and 1/10 of the chronic cases. Alcohol consumption was more than 50g/day in nearly half of the patients. Acute pancreatitis was dominated by a high leukocyte count, hyperbilirubinaemia, raised aminotransferases and blood glucose levels, and low albumin and calcium levels in serum. In chronic pancreatitis 1/3 had steatorrhoea; 1/6 regularly used morphine, and 1/4 had impaired liver function. It is concluded that the incidence rates of acute and chronic pancreatitis in Copenhagen seem to be higher than those reported elsewhere; however, differences in diagnostic criteria may play a role. The clinical and laboratory findings are in agreement with other studies.
KW - Abdomen, acute condition
KW - Alcohol drinking
KW - Amylase
KW - Blood sugar
KW - Calcium
KW - Cholelithiasis
KW - Epidemiology
KW - Liver disease
KW - Morphine
KW - Pancreatic disease
KW - Pancreatitis
KW - Prospective studies
U2 - 10.3109/00365528109181973
DO - 10.3109/00365528109181973
M3 - Journal article
C2 - 7313541
AN - SCOPUS:0019524138
VL - 16
SP - 305
EP - 312
JO - Scandinavian Journal of Gastroenterology. Supplement
JF - Scandinavian Journal of Gastroenterology. Supplement
SN - 0085-5928
IS - 2
ER -