Abstract
The aim of the present study was to investigate whether the adjuvanticity of the cholera toxin B (CTB) subunit was correlated with its immunogenicity in young orally immunised chickens. Thirteen 15-day-old chickens were orally immunised with bovine serum albumin (BSA) glutaraldehyde coupled to CTB. The chicken antibody (IgG) concentrations against BSA and CTB, respectively, were quantified by ELISA. A significant positive correlation (r=0.66, n=39, p<0.001) between the concentrations of immunospecific antibodies with specificities against BSA and CTB, respectively, demonstrated that the adjuvanticity of CTB is correlated with its immunogenicity.
Originalsprog | Engelsk |
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Tidsskrift | APMIS |
Vol/bind | 113 |
Udgave nummer | 4 |
Sider (fra-til) | 284-287 |
Antal sider | 4 |
ISSN | 0903-4641 |
DOI | |
Status | Udgivet - apr. 2005 |