@article{821c39a067df11df928f000ea68e967b,
title = "Cranial nerve palsy in Wegener's granulomatosis--lessons from clinical cases",
abstract = "The problem of diagnosing vasculitic neuropathy is discussed based on case reports of two patients with Wegener's granulomatosis. One patient developed de novo 6(th) nerve palsy as an isolated relapse manifestation and the second patient a sequence of multiple cranial nerve palsies. Brain imaging with CT and MRI and the laboratory provided no clues suggesting active vasculitis. However, in both patients the neuropathies fully recovered in response to standard induction protocols of vasculitis. In the absence of organ-specific proof of vasculitis, these treatment decisions were guided by the overall clinical presentations. Cranial neuropathy may be the first obvious vasculitic manifestation preceding other organ disease, and since single reliable tests for its diagnosis are lacking, a multidisciplinary approach is advocated here to detect vasculitic manifestations in other organs.",
author = "Rainer Nowack and Paul Wachtler and J{\"u}rgen Kunz and Niels Rasmussen",
note = "Keywords: Adult; Aged; Brain; Cranial Nerve Diseases; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Male; Tomography, X-Ray Computed; Vasculitis, Central Nervous System; Wegener Granulomatosis",
year = "2009",
doi = "10.1007/s00415-009-0121-1",
language = "English",
volume = "256",
pages = "299--304",
journal = "Journal of Neurology",
issn = "0340-5354",
publisher = "Springer Medizin",
number = "3",
}