CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner

Mark O Huising, Talitha van der Meulen, Joan M Vaughan, Masahito Matsumoto, Cynthia J Donaldson, Hannah Park, Nils Billestrup, Wylie W Vale

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

67 Citationer (Scopus)

Abstract

Udgivelsesdato: 2010-Jan-12
OriginalsprogEngelsk
TidsskriftProceedings of the National Academy of Science of the United States of America
Vol/bind107
Udgave nummer2
Sider (fra-til)912-7
Antal sider5
ISSN0027-8424
DOI
StatusUdgivet - 2009

Bibliografisk note

Keywords: Adrenalectomy; Animals; Cell Division; Cell Line, Tumor; Cyclic AMP; DNA, Complementary; Flow Cytometry; Glucose; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Insulinoma; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Postprandial Period; Rats; Receptors, Corticotropin-Releasing Hormone

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