TY - JOUR
T1 - Cutaneous vasoconstriction affects near-infrared spectroscopy determined cerebral oxygen saturation during administration of norepinephrine
AU - Holm-Sørensen, Henrik
AU - Secher, Niels H.
AU - Siebenmann, Christoph
AU - Nielsen, Henning M Bay
AU - Kohl-Bareis, Matthias
AU - Lundby, Carsten
AU - Rasmussen, Peter
PY - 2012
Y1 - 2012
N2 - Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.
AB - Perioperative optimization of spatially resolved near-infrared spectroscopy determined cerebral frontal lobe oxygenation (scO2) may reduce postoperative morbidity. Norepinephrine is routinely administered to maintain cerebral perfusion pressure and, thereby, cerebral blood flow, but norepinephrine reduces the scO2. We hypothesized that norepinephrine-induced reduction in scO2 is influenced by cutaneous vasoconstriction.
U2 - 10.1097/ALN.0b013e3182605afe
DO - 10.1097/ALN.0b013e3182605afe
M3 - Journal article
C2 - 22739762
SN - 0003-3022
VL - 117
SP - 263
EP - 270
JO - Anesthesiology
JF - Anesthesiology
IS - 2
ER -