TY - JOUR
T1 - Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep
AU - Randerath, Winfried
AU - Verbraecken, Johan
AU - Andreas, Stefan
AU - Arzt, Michael
AU - Bloch, Konrad E
AU - Brack, Thomas
AU - Buyse, Bertien
AU - De Backer, Wilfried
AU - Eckert, Danny Joel
AU - Grote, Ludger
AU - Hagmeyer, Lars
AU - Hedner, Jan
AU - Jennum, Poul
AU - La Rovere, Maria Teresa
AU - Miltz, Carla
AU - McNicholas, Walter T
AU - Montserrat, Josep
AU - Naughton, Matthew
AU - Pepin, Jean-Louis
AU - Pevernagie, Dirk
AU - Sanner, Bernd
AU - Testelmans, Dries
AU - Tonia, Thomy
AU - Vrijsen, Bart
AU - Wijkstra, Peter
AU - Levy, Patrick
N1 - Copyright ©ERS 2017.
PY - 2017
Y1 - 2017
N2 - The complexity of central breathing disturbances during sleep has become increasingly obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing with apnoeas, or irregular breathing in patients with cardiovascular, other internal or neurological disorders, and can emerge under positive airway pressure treatment or opioid use, or at high altitude. As yet, there is insufficient knowledge on the clinical features, pathophysiological background and consecutive algorithms for stepped-care treatment. Most recently, it has been discussed intensively if CSA in heart failure is a "marker" of disease severity or a "mediator" of disease progression, and if and which type of positive airway pressure therapy is indicated. In addition, disturbances of respiratory drive or the translation of central impulses may result in hypoventilation, associated with cerebral or neuromuscular diseases, or severe diseases of lung or thorax. These statements report the results of an European Respiratory Society Task Force addressing actual diagnostic and therapeutic standards. The statements are based on a systematic review of the literature and a systematic two-step decision process. Although the Task Force does not make recommendations, it describes its current practice of treatment of CSA in heart failure and hypoventilation.
AB - The complexity of central breathing disturbances during sleep has become increasingly obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing with apnoeas, or irregular breathing in patients with cardiovascular, other internal or neurological disorders, and can emerge under positive airway pressure treatment or opioid use, or at high altitude. As yet, there is insufficient knowledge on the clinical features, pathophysiological background and consecutive algorithms for stepped-care treatment. Most recently, it has been discussed intensively if CSA in heart failure is a "marker" of disease severity or a "mediator" of disease progression, and if and which type of positive airway pressure therapy is indicated. In addition, disturbances of respiratory drive or the translation of central impulses may result in hypoventilation, associated with cerebral or neuromuscular diseases, or severe diseases of lung or thorax. These statements report the results of an European Respiratory Society Task Force addressing actual diagnostic and therapeutic standards. The statements are based on a systematic review of the literature and a systematic two-step decision process. Although the Task Force does not make recommendations, it describes its current practice of treatment of CSA in heart failure and hypoventilation.
KW - Advisory Committees
KW - Analgesics, Opioid/therapeutic use
KW - Europe
KW - Humans
KW - Hypoventilation/etiology
KW - Polysomnography
KW - Positive-Pressure Respiration
KW - Practice Guidelines as Topic
KW - Review Literature as Topic
KW - Sleep
KW - Sleep Apnea, Central/diagnosis
U2 - 10.1183/13993003.00959-2016
DO - 10.1183/13993003.00959-2016
M3 - Journal article
C2 - 27920092
VL - 49
JO - The European Respiratory Journal
JF - The European Respiratory Journal
SN - 0903-1936
IS - 1
M1 - 1600959
ER -