Dermal pharmacokinetics of microemulsion formulations determined by in vivo microdialysis

Mads Kreilgaard

doi:10.1023/A:1011067300397

Dermal pharmacokinetics of microemulsion formulations determined by in vivo microdialysis

Mads Kreilgaard

LUKKET: Pharmacotherapy

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

102 Citationer (Scopus)

Abstract

To investigate the potential of improving dermal drug delivery of hydrophilic and lipophilic substances by formulation in microemulsion vehicles and to establish a reliable pharmacokinetic model to analyze cutaneous microdialysis data.

Originalsprog	Engelsk
Tidsskrift	Pharmaceutical Research
Vol/bind	18
Udgave nummer	3
Sider (fra-til)	367-73
Antal sider	7
ISSN	0724-8741
DOI	https://doi.org/10.1023/A:1011067300397
Status	Udgivet - mar. 2001

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Citationsformater

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title = "Dermal pharmacokinetics of microemulsion formulations determined by in vivo microdialysis",

abstract = "To investigate the potential of improving dermal drug delivery of hydrophilic and lipophilic substances by formulation in microemulsion vehicles and to establish a reliable pharmacokinetic model to analyze cutaneous microdialysis data.",

keywords = "Administration, Topical, Algorithms, Animals, Chromatography, High Pressure Liquid, Diffusion, Emulsions, Male, Microdialysis, Rats, Rats, Wistar, Reproducibility of Results, Skin Absorption",

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year = "2001",

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T1 - Dermal pharmacokinetics of microemulsion formulations determined by in vivo microdialysis

AU - Kreilgaard, Mads

PY - 2001/3

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N2 - To investigate the potential of improving dermal drug delivery of hydrophilic and lipophilic substances by formulation in microemulsion vehicles and to establish a reliable pharmacokinetic model to analyze cutaneous microdialysis data.

AB - To investigate the potential of improving dermal drug delivery of hydrophilic and lipophilic substances by formulation in microemulsion vehicles and to establish a reliable pharmacokinetic model to analyze cutaneous microdialysis data.

KW - Administration, Topical

KW - Algorithms

KW - Animals

KW - Chromatography, High Pressure Liquid

KW - Diffusion

KW - Emulsions

KW - Male

KW - Microdialysis

KW - Rats

KW - Rats, Wistar

KW - Reproducibility of Results

KW - Skin Absorption

U2 - 10.1023/A:1011067300397

DO - 10.1023/A:1011067300397

M3 - Journal article

C2 - 11442278

SN - 0724-8741

VL - 18

SP - 367

EP - 373

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 3

ER -